Other highlights in the February 2 JNCI
...olorectal cancer in 2001 received inadequate lymph node evaluation to see if their cancer had spread, according to a new study. Lymph node status is the strongest predictor of outcome for colorectal cancer patients. Only 40% of patients wi...Poor response to chemotherapy does not mean poor outcome for patients with rare breast cancer
...t of women with lobular cancers had residual lymph node disease compared to 26 percent of women with ductal disease. Yet, five years after treatment, breast cancer had not come back in 80 percent of women with lobular carcinoma, compared with 66 percent of ductal carcinoma patients. And five-year survival...New data sets survival benchmark for Pfizer's ELLENCE
...n integral component of treatment of patients with node positive breast cancer," said William Gradishar, MD, Associate Professor of Medicine in the Division of Hematology and Medical Oncology at Northwestern University Medical School. "Patients stand to benefit from the significant outcome advantages del...New biopsy technique helps assess breast cancer's spread
...ead to the axilla, or underarm, are sentinel lymph node sampling, in which the first lymph node is identified and assessed for cancerous cells, or axillary lymph node dissection, in which all the ...Pioneering Welsh surgery delivered to hospitals
...d England means that the main gland - the sentinel node - can now be traced using a small dose of radioactivity to find out whether the cancer has spread. Women found not to have cancer spread, will no longer have to have such invasive surgery 'just in case' of cancer spread....Early disclosure: Post-operative radiotherapy improves progression-free survival in prostate cancer
...cal prostatectomy. Trial participants had no lymph node involvement and no metastatic disease but all displayed high risk factors for local disease recurrence (e.g. capsule perforation, positive margins or involvement of seminal vesicles). The trial ran from 1992 - 2001 and, following review by an indepen...Novel imaging technique shows lymph nodes, metastases in breast cancer without surgery
...ct inspection can render it less than clear. Which node is the sentinel, closest in flow from the breast? Which in line after that should be the last to take? Also, lymphatic vessels are not always easy just to find. Theyre not like bone or a major organ, Brechbiel points out. The NCI research has the pot...Breast cancer in men increasing
...2.6 percent). Larger tumor size and axillary lymph node disease were independently associated with shortened survival. Tumor grade and receptor status were not. The authors conclude: "this data suggests that the incidence of male breast cancer is climbing, men are diagnosed with later stage disease than w...New research in atrial fibrillation
...r node, the point at which they meet. The modified node would not be able to conduct impulses from the upper to the lower chambers of the heart. "This has been shown to work in animal models of chronic disease and would be in line for clinical trials in perhaps three to five years," said Dr. Donahue. "In ...Thoracic PET appropriate for diagnosing some lung cancer patients
...s. All patients with distant metastases had lymph node disease, Dr. Aquino said. One patient had a distant metastasis only seen on whole body PET. She had advanced nodal disease, and therefore her management would not have significantly changed following the whole body PET examination, Dr. Aquino said....Extended lymph node dissection fails to increase long-term survival among gastric cancer patients
Alexandria, VA-- Extended lymph node dissection a treatment for gastric cancer involvi...est randomized trial of limited and extended lymph node dissection among this population. Gastric cancer is the fourth most common type of cancer worldwide...OHSU researchers, collaborators make recommendations to self-treating physicians
...think the needle biopsy done on his enlarged lymph node was the correct procedure to rule out lymphoma, but that he didn't challenge his doctor's decision because he wanted to be a "good patient." Furthermore, the study authors report notable advantages of self-doctoring, such as the ability to schedule ...Nanotech imaging, molecular fingerprints and signatures hold promise for cancer
... "In breast cancer patients, the presence of lymph node metastases greatly affects the prognosis, and the ...sis is evident to be contained within the sentinel node and not in downstream lymphatic structures." The key to maximizing performance of G6 as a contra...Conservation treatment or mastectomy for DCIS?
...er cent similar to patients diagnosed with small, node negative cancer. "The ten-year rate of deaths from all causes and from breast cancer specifically is statistically similar across all three groups. Therefore, regardless of their initial treatment, the three groups of patients had similar rates of s...Addition of rituximab to standard chemotherapy does not influence response rates in older ...
...e a quickly growing mass in the body or in a lymph node that patients can feel. Although it usually starts in lymph nodes, DLBCL can grow in other areas, such as the bones, the brain, or the spinal cord. About one-third of these lymphomas are confined to one part of the body. When it is confined, DLBCL...Major advance in chemotherapy in breast cancer
...ding tissue and spread through the blood and lymph node system. An estimated 211,300 women in the U.S. will be diagnosed with breast cancer this year, and an estimated 40,000 women will die from the disease. Worldwide, almost 1 million women are diagnosed with this disease each year. In the United Stat...New computerized tool predicts chance of breast cancer's spread
...es under the arms (axilla). Further axillary lymph node metastasis is a key factor in determining whether ...of the primary breast tumor and the sentinel lymph node metastasis of 702 breast cancer patients. Using that information, they developed nomogram calculatio...Breast conserving therapy offers good outcome if criteria are met
...k of local-regional recurrence: advanced lymph node disease at presentation a poor response to chemotherapy as evidenced by a pathological primary size greater than 2 centimeters after use of chemotherapy a tumor that did not shrink down in a single piece, like a balloon, after chemotherapy, but broke...Understanding how lymph nodes respond to infection may redefine how immune system functions
...hows how the immune system functions and the way a node responds to an infectious agent, you are going to see a whole new pathway," said Pizzo. "Mast cells are much more than just bad actors making you feel sick when you are exposed to noxious agents. They are actually major players helping you deal with ...Outpatient treatment shrinks liver tumors to acceptable size for laser procedure
... said it has applications for lung, bone and lymph node tumors as well. "These procedures are FDA accepted, and they're starting to be used all over Europe," he said....