Mice lacking fat-making enzyme are leaner, more sensitive to leptin and insulin
...researchers showed that in a strain of genetically obese mice characterized by leptin resistance, inactivation of DGAT1 significantly reduced their obesity and insulin resistance. Obesity is a huge public health problem, so people are looking for drugs to cure it, said Robert V. Farese, Jr., MD, senior aut...Obese lung-transplant recipients at higher risk of death
...e clinical experience of transplant programs, that obese patients probably have higher morbidity and shorte...tigators. Our findings also highlight the need for obese patients to participate actively in a weight-reduction program before transplantation, he said. The...Simple blood test may be able to predict risk of preeclampsia
...her women were lean or overweight. "We know that obese women are at higher risk for preeclampsia and tend to have insulin resistance," Wolf says. "The fact that the association of preeclampsia with reduced first-trimester SHBG is also seen in lean women suggests that insulin resistance may be the true r...Energy expenditure differs by race, sex, and weight among Louisiana school children
...considered lean if they had <25% body fat and obese if they had 25% body fat. As a group, the boys ha...ates and energy expenditures also differed between obese and lean children. Obese children had a higher RMR and a lower AEE than did lean children, with the ...Waist circumference and body mass index predict body fat and disease risk
... three BMI groups (normal, overweight, and class I obese between 30 and 35) and 3 WC (low, intermediate, and high). Within each BMI category, those in the high WC category had substantially greater abdominal fat compared to those in the low WC category. Though BMI and WC each independently predicted nonab...Key predictors of heart disease in women develop as early as adolescence
...diography should be considered a screening tool in obese adolescent and young adult women to identify those...merican women were significantly more likely to be obese than Caucasian women. In the study, 33 percent of African American women were obese, and 16 percent ...Many obese youth have condition that precedes type 2 diabetes
Many obese children and adolescents have impaired glucose tol...ournal of Medicine. "This study suggests that many obese children have a high risk for developing type 2 diabetes," said HHS Secretary Tommy G. Thompson. "...Yale study shows 25 percent of obese children are at high risk for developing diabetes
New Haven, Conn. Twenty five percent of obese children and 21 percent of obese adolescents tested by Yale researchers were glucose intolerant and at high risk for developing diabe...Obesity, stress among factors predicting high health care costs
...le with high stress were 1.9 times more likely and obese people were 1.7 times more likely to have expenses at that level, the researchers found. The study participants were 18 to 68 years of age, with an average age of 32 years. More than half of the participants (55.7 percent) were women, and most of the...American Thoracic Society Journal news tips for March (first issue)
...e Medicine. Sleep-disordered breathing in mildly obese men associated with glucose intolerance and insuli...dying a community sample of 135 healthy but mildly obese men found that moderate to severe sleep-disordered breathing (SDB), as measured by a sleep test, was...Obesity growing threat to world health
...yond. In 1995, there were an estimated 200 million obese adults and 22 million children worldwide. By 2000, the number had skyrocketed to more than 300 million. In developing countries, it is now estimated that more than 115 million people suffer from obesity-related problems, including Type II Diabetes, ...Study shows weight loss with an antidepressant medicine in combination with lifestyle intervention
...d exercise, resulted in significant weight loss in obese patients up to 24 weeks. Further, a 24-week exten...eight loss and has not been studied extensively in obese patients. Study Design This multi-center, double-blind, randomized study compared the changes in we...Maternal feeding practices are linked to childhood obesity
... has become a vital public health priority because obese children are much more likely to become obese adults. Although factors such as the sex, ethnicity or socioeconomic status of the child have been ...Mothers attitudes toward childrens eating linked to childrens obesity
...can children is considered obese. Children who are obese tend to become obese adults, and obesity is associated with numerous health concerns such as cardiovascular disease, resp...Mayo Clinic Proceedings looks at epidemic of obesity in February issue
... percent were overweight or obese. Overweight and obese women reported low self-efficacy for exercise and eating, suggesting that interventions should focus on increasing self-efficacy for behavior change. Other authors in the study include: Nancy C. Maruyama, M.D., of the Department of Consultation-Liais...CRP provides another reason to lose weight and gain heart health
...ater Burlington, Vt., area. The study included 61 obese postmenopausal women, average age 56. Obesity is ...plasma CRP levels. Other studies have shown that obese patients are usually characterized by increased plasma CRP, possibly because fat tissue releases a f...Heavier white female workers earn less
.... It has repeatedly been found, for example, that obese workers are more likely to miss work due to illness. However, this explanation is complicated by the fact that the analysis finds no evidence that weight lowers wages for black women." Nevertheless, he points out that the finding that weight lowers...New data shows rapid and sustained weight loss with Xenical
...eight loss medication Xenical helps overweight and obese people lose weight rapidly and is associated with rapid improvements in cardiovascular risk factors according to preliminary results of new research being presented at the North American Association for the Study of Obesity (NAASO) meeting in Qubec C...Providing a bigger view: New imaging device offers better conditions for cancer treatment planning
...ws for full imaging of cancer regions in large and obese patients, who sometimes have trouble entering the smaller openings. It also enables oncologists to get a more accurate view of a patient's body dimensions which helps them to calculate more accurately the appropriate radiation for cancer treatment. ......ek course of therapy with Avandia on non-diabetic, obese patients at risk for cardiovascular disease. Avan...rosclerosis. The study involved 11 non-diabetic obese patients who were given 4 mg of rosiglitazone daily for a period of six weeks. Fasting blood sample...