U-M Researcher Addresses Changes In The Heart As It Ages
...se doesn't occur suddenly. It's aprogression that occurs over time and is influenced by gradual changes thatweaken the heart. These changes begin early in life with arterial stiffening in the teen years. By age 20, your maximum heart rate begins to slow by one beat a year and by age30, you begin to produce......le." Osteoporosis is an age-related disease that occurs primarily in post-menopausalwomen due to loss of estrogen. The disease is characterized by persistent lossof bone mass and afflicts more than 28 million people in the U.S. and over 200million people worldwide, approximately 80% of whom are women. Es...Study Confirms Safety Of Common Heart Drug
...bloodconcentrations in hospitalized patients often occurs too soon after they takethe drug. In nearly 16 percent of the patients studied, serum digoxinconcentrations were sampled six hours or less after a dose was given -- beforecomplete distribution of the drug throughout the body. "If elevated, theseconc......enopausal women against the rapidloss of bone that occurs after menopause and often leads to thinning bones,osteoporosis and fractures. Besides its effects on the breast, raloxifene hasbeen shown to protect postmenopausal women against bone loss andosteoporosis-related fractures and also lowers cholesterol....... However, Filbin has found that no blocking effect occurs if the neuron isexposed to neurotrophins and MAG or myelin at the same time. The neuron must be"primed" first. Filbin co-authored the article, "Prior Exposure to Neurotrophins BlocksInhibition of Axonal Regeneration by MAG and Myelin Via a cAMP-Depe...Heart Valve Abnormalities Examined In Relation To Duration Of Diet Drug Use
... leakage," Ryan said. Aortic regurgitation occurs when blood leaks from the aorta -- the largeartery that distributes blood to the body -- back through the aortic valve intothe left ventricle, the heart's main pumping chamber. Ryan said that while thelikelihood of developing the leaking valve increa......ten fatal, inflammatory lung condition thatusually occurs in conjunction with catastrophic medical conditions, such aspneumonia, shock, sepsis, and trauma. Approximately 150,000 Americans areaffected each year, and more than 40 percent die. No specific therapies currently exist for these patients. ...Chemists Discover That Aerosol Clusters Play Larger Role In Generation Of Air Pollution
...utant. "This is a brand-new chemical reaction that occurs only inside these clusters,"said Garvey, a fact that he noted hopefully will attract more attention to therole that these clusters play in air pollution. "This is only the tip of the iceberg," said Garvey. "It leads us to believethere may be a rich...Wake Up To Stroke -- Night Strokes Linked To Long Delays In Care
...emic stroke, the most common type of stroke, which occurs when blood flow isimpeded by a blocked artery in the brain. Stroke is the No. 3 cause of deathand a major cause of disability in the United States. About 600,000 strokesoccur each year, 160,000 of which are fatal. In the study, 559 patients with st...Emory Receives $14 Million Federal Grant To Coordinate 50-Site Brain Attack Prevention Trial
...n of the study. A stroke or "brain attack" occurs when blood circulation to the brainbecomes interrupted. The most common type of stroke, ischemic stroke, occurswhen an artery narrows or a blood clot blocks blood flow in an artery supplyingthe brain. A clot can form because of sluggish blood flow t...Trial Begins For First Artificial Liver Device Using Human Cells
... rapidlyworsening liver dysfunction that primarily occurs in young, healthy people.Although the cause is often unknown, FHF can result from viral liver infections,exposure to particular toxins, or to certain drugs, such as an overdose ofacetaminophen. FHF can cause multi-organ failure, brain damage and deat...A Note of Caution: Be Careful When Mixing Grapefruit Juice With Rxs
...(for alleviating allergy symptoms) This inhibition occurs because an unknown substance in grapefruit juiceactivates one of the body's naturally-produced drug efflux mechanisms, known asP-glycoprotein, located in the intestinal tract. When grapefruit juiceinteracts with P-glycoprotein, the result is an incr...NICHD-Funded Researchers Show Estrogen Effects On Brain After Menopause
...echnology measures the increase in blood flow that occurs in active areas ofthe brain. The researchers compared brain activation patterns in postmenopausalwomen when they were taking estrogen to when they were taking a placebo. Theyfound that estrogen changed the brain activation patterns of the postmenop...Baby Talk: Parents Do Make A Difference, By Promoting Childhood Chatter, From Birth To Age 3
..., Golinkoff says.Research suggests that this spurt occurs after children have accumulatedanywhere from 30 to 100 words. At that point, they form simple sentences suchas, "More juice," and they may ask repeatedly, "Watssat?" or "Whatdat?" meaning,"What's that?" Now more than ever, Hirsh-Pasek emphasizes: "Yo......ingsshow the "healing" that happens after a stroke occurs at a high level oforganization, demonstrating the plasticity of the human brain long intoadulthood. Such plasticity was routinely credited to the brain in the first fewyears of life. The research team consists of Dr. Keith Thulborn of ...Migraine Pain: Not Mainly In The Brain
...ssubsided, as abaseline. During inflammation that occurs during a migraine, Pappagallo says,blood vessels in the meninges become unusually permeable to molecules such asalbumen. The SPECT scans then pick up the albumen leakage into surroundingtissues. The images showed bright, diffuse patches -- ...... WASHINGTON, D.C., April 21 -- Organ rejection occurs less often and is lesssevere in patients who recei...commoncomplication of bone marrow transplantation, occurs when donor immune cellsattack recipient tissues. In addition to Drs. Rao and Starzl, other authors o...Study Reveals Gender Affects Lung-Cancer Development
...is disease. Approximately 50 percent of lungcancer occurs in former smokers. Women are more susceptible to the harmfuleffects of tobacco-related carcinogens - the odds ratios for major types of lungcancer are consistently higher in women than in men at every level of exposureto cigarette smoke. Furthermore,...Statement from Claude Lenfant, M.D., NHLBI Director, on Trends in Hypertension
...t themajority of coronary heart disease and stroke occurs at lower stages ofhypertension. And, although hypertension levels declined over the 4 decadesbetween 1950 and 1989, recent data from the National Health andNutrition Examination Survey (NHANES) reveal that a national downward trend inblood pressure c...... SAN FRANCISCO, April 24 -- Organ rejection occurs less often and is less severein heart and lung tra...commoncomplication of bone marrow transplantation, occurs when donor immune cellsattack recipient tissues. "The results in these patients who received the ext...