Impulsiveness, aggression, alcohol and adolescents
...oholism, which is found in both males and females, occurs later in life, and is not associated with antisocial traits.) Research suggests that there is a biologic (and possibly hereditary) basis for the temperament of impulsivity that is related to dysregulation of the neurotransmitter serotonin in the par...European commission grants "orphan" status for new acute myeloid leukaemia treatment
... chemotherapeutic agents. Severe myelosuppression occurs when Mylotarg is used at recommended doses. In clinical trials the adverse event profile for Mylotarg was consistent with the drug's targeted nature. No alopecia (hair loss) was seen. Additionally, no cardiotoxicity or cerebellar toxicity was repo...There are a few 'safe' days in menstrual cycle
... new report they find that sporadic late ovulation occurs even in women who say their cycles are usually regular. Because of these late ovulations, the researchers show, 4 to 6 percent of women are potentially fertile in the fifth week - more than 28 days after the start of their cycle. Having intercou...Insulin precursor linked with increased stroke risk; may represent new risk factor
...ood. "The conversion of proinsulin to insulin occurs in several steps, mainly in the secretory granules in the beta cells of the pancreas, explains Lindahl. "The ratio of proinsulin to insulin in the blood stream is frequently increased in diabetes patients, possibly because high blood levels of gluco...Sustained use of anti-depressants increases cell growth and protects cells in the brain
...w regions of the brain where production of neurons occurs in the adult brain of animals, including humans. Several studies have demonstrated that stressful experiences, both physical and psychological, lead to neuronal loss or atrophy in the hippocampus. Other studies show that anti-depressants can block th...University of Toronto researchers develop potent vaccine for Alzheimer's
...ent (dementia) of Alzheimer's disease. Alzheimer's occurs when toxic biochemical compounds known as amyloid peptides accumulate in the brain, forming amyloid plaque deposits and injuring nerve cells, eventually causing dementia. While previous studies have shown that vaccinating transgenic mice with this p...... damage are most likely to succeed if intervention occurs within the first several hours. In addition, evidence exists that an attack in the other eye occurs up to 15 % of the time, over the following five years. Currently, a daily dose of aspirin is the on......ments, while up to 10 times the amount of violence occurs in the community than is reported to the police. So the authors say that hospital data are likely to be an accurate reflection of national trends in violence....Teenagers, drinking and driving: a quick trip to the grave
...y seven years following licensure, which typically occurs during or shortly after 10th grade. The study had three main findings. "They found that the curriculum reduced serious traffic offenses, both alcohol-related offenses and other offenses as well, by about 20 percent in the first year these kids wer...Study: Ripped aortas kill often, but new knowledge may aid survival
...84 patients found to have Type B dissection, which occurs in the descending portion of the aorta at or below the first branch leading to the arms, the overall mortality of 11 percent was higher than expected. But the study doesn't include enough data on how patients with different symptoms, risk factors and...License agreement signed to commercialize intelligent hearing aid
... their time of arrival much like the process that occurs in the human brain. "Normal hearing exploits the fact that we have two ears," said Doug Jones, a UI professor of electrical and computer engineering and a member of the Beckman team. "Our brains utilize both the time of arrival and the intensity of ...Hopkins researcher finds retroviral 'footprint' in brains of people with schizophrenia
.... "While a low level of retrovirus expression occurs in most human tissues, we found an unexpectedly high level of expression in the cerebrospinal fluids from individuals whod had a recent onset of schizophrenia," says Yolken, director of the Stanley Division of Developmental Neurovirology and a princi......either modestly effective or poorly tolerated. IDH occurs most often in dialysis patients who are older, people with diabetes or heart disease, and people whose bodies cannot automatically compensate for dialysis-induced fluid loss by constricting the blood vessels to maintain blood return to the heart. The...Safer estrogen targets painful intercourse in older women
..., the medical term for vaginal atrophy, most often occurs in women after menopause. Studies have shown that more than 40 percent of postmenopausal women experience the condition, which causes thinning of the vaginal wall, dryness and itching, and leads to painful intercourse and sometimes bleeding. In addi...Early trial at Thomas Jefferson University Hospital shows Angiostatin is safe
... tumors without directly destroying tumor cells as occurs with chemotherapy or radiation, is to develop means for determining which patients would benefit from continued treatment,"Dr. Capizzi says. The drug's lack of toxicity was a pleasant surprise. "The fact that we got through five doses with little or ...Researchers gain insights on pulmonary fibrosis
...enetics in Vienna, Austria. Pulmonary fibrosis occurs when the thin layer of tissue around the lung's alveoli -- the tiny air sacs where gases are exchanged with the blood -- becomes damaged. The resulting scar tissue limits the lung's ability to take in oxygen and get rid of carbon dioxide. There are m...Researchers to test skeletal muscle as replacement for damaged human heart muscle in humans
... heart during an extended period of low oxygen, as occurs in a severe heart attack. Although the remaining healthy heart muscle cells grow larger to compensate, that only makes the heart more inefficient, ultimately leading to heart failure, which kills more than 410,000 people annually in the United States...Natural immune response reduces nerve damage; may lead to improved treatment for spinal cord injury
... thereby inhibit the cascade of normal damage that occurs after the initial trauma, such as spinal cord injury. In four experiments in rats and mice, Schwarz and colleagues Eti Yoles and Ehud Hauben found that central nervous system trauma evokes a protective immune response that reduces neuronal loss. Th...PET scans identify breast-cancer patients who will respond to hormone therapy
...r whether her cancer is progressing. The problem occurs because hormone therapy stimulates breast tumors t...erapy have a temporary flare reaction, but that it occurs subclinically in most cases, said Mortimer. The researchers further proposed that this subclinical f......ne. Type 2 diabetes is a complicated disorder that occurs when sufferers develop a resistance to otherwise perfectly normal insulin. The insulin secreting cells of the pancreas are unable to compensate by making more of the hormone. In healthy individuals, insulin triggers a series of events that allows cer...