Early heart disease in parents linked to thicker artery walls in offspring
...n the Framingham Offspring Study, a study of 5,124 offspring (and their spouses) of the original participants i...inal Framingham study. Between 1995 and 1998, the offspring underwent carotid ultrasound imaging to measure their carotid walls. This noninvasive imaging techn...Stanford, Packard research finds better drug therapy for children predisposed to bipolar disorder
...evelop the disease. Researchers studied 23 bipolar offspring between the ages of 6 and 18 who had attention-def...risk. Previous studies have estimated that bipolar offspring have up to a 24 percent chance of developing the disease, and ADHD might be a predictor. Researchers...Sex selection for social reasons: religious and moral perspectives
...ke. It is simply assumed that selecting the sex of offspring is a matter of preference and not morality. Yet it is at least arguable that parenthood is characterized by the unconditional rather than conditional acceptance of children, a quality that is clearly eroded by the availability of sex selection techno...Coping behaviors linked to female chromosome
...h behavioral and genetic evidence for X-linkage in offspring of two strains of rats that exhibited differing coping behaviors. First-generation males but not females showed maternally derived coping styles, while second-generation females -- but not males -- showed significant differences in coping styles dete...A pair of discoveries helps unravel complex genetics of inflammatory bowel disease
...and the University of Pittsburgh) in which 131 had offspring with ulcerative colitis for evidence of a link between the disease and the NFKB1 gene. They found six variants of the gene, and showed that one variant - involving a small deletion of the NFKB1 gene sequence - influences the amount of NFKB1 gene pro...Metabolic syndrome may be an important link to stroke
...iabetes-free participants (average age 59) of the offspring cohort in the Framingham Heart Study. Men and women were evaluated for a current diagnosis of diabetes and the five metabolic syndrome components: abdominal obesity (waist circumference greater than 35 inches in women and greater than 40 inches in ...Young people prone to type 2 diabetes exhibit alterations in mitochondrial activity
... the development of type 2 diabetes in young, lean offspring of parents with the disease. They demonstrated ... that insulin resistance in muscle of the diabetic offspring was accompanied by an increase in muscle cell lipid content. Shulman, an investigator at the Ho...American Thoracic Society Journal news tips for February 2004 (second issue)
...smoking synergizeto increase airflow limitation in offspring Mothers who have smoked adversely affect their ...maternal smoking: lowers lung function whether the offspring personally smoke or not; was associated with greater smoking intensity in their children and less ab...Thursday, March 4, 2004 news tips
...he 5,124 men and women, aged 5 to 70 years, in the offspring cohort enrolled in 1971-1975. Of these serious cancers, 1,654 appeared between 1949 and 1999 in subjects 37-97 years old. Each cancer case was matched to two subjects of the same generation by age, sex and whether the subjects already had documente...America's teens: Growing up and out
...ears, from 1971 to 1981, with that of 228 of their offspring when they were the same age, in 2001 to 2003. They found that body mass index (BMI), a measure of obesity, increased from 22.97 to 24.24 among boys and from 21.9 to 24.4 among girls from 1971-1981 to 2001-2003. A BMI of 18.5 to 24.9 is considered to...OHSU receives grant to study evolutionary computing for biomedical image analysis
...els did it get right?" said Mitchell. "Most of the offspring do horribly, but there are ones that do better than others," she said. "The ones that do better get to have more children, and some of their children will do even better." A complete run of tens to hundreds of generations can take several hours or m...Light to moderate drinking during pregnancy may lead to learning and memory deficits in adolescents
...ubtle difficulties with learning and memory in the offspring at 14 years of age, specifically in the auditory/verbal domain. "This indicates that drinking during the first trimester of pregnancy has long-term effects on development. Many women do not realize they are pregnant and/or seek prenatal care durin...Mothers' cells can cause immunity illness in children
...pects of chimeric cells. First, they remain in the offspring after birth and are related to the HLA genes, and second, chimeric cells are not merely present in the children -- but they are active, as shown by the attacks they mount against the child's body. ...Emory researcher examines effects of antiepileptic drugs on pregnant women and their offspring
...earchers are also learning that effects of AEDs in offspring may not be so instant. "We are recognizing that we need to not only be concerned about birth defects from the AEDs, but also about cognitive effects later in the child's life," says Dr. Pennell. "At two years of age, we are realizing some of these ch...Preimplant test offers option of having child to serve as stem cell donor to sibling in need
...termine if the tissue type matches and the ensuing offspring could potentially serve as a donor to the affected child, according to a study in the May 5 issue of The Journal of the American Medical Association (JAMA). Preimplantation genetic diagnosis (PGD) has become available as an alternative to prenatal ...Parents' heart attack or stroke raises risk in their middle-aged children
...t on the true magnitude of the association between offspring and parental cardiovascular disease, said Donald M...y to examine the true relationship of parental and offspring cardiovascular disease, confirmed by a physician panel of experts, without the potential bias of oft...New UNC, EPA 9/11 study suggests that pollutants posed small cancer risks
...rned that there might be harmful effects among the offspring of women living nearby who were or became pregnant at the time these exposures occurred," Rappaport said. "A particular effect that has been associated with PAH exposure is a condition known as intrauterine growth restriction (IUGR), which results in...Mothers have brains primed for care
...o her. In rats, these behaviors include retrieving offspring who try to wander off, protecting young from preda... and reduced fear and anxiety responses to leaving offspring or confronting predators and prey in their environment, Kinsley says. Kinsley and his colleagues ex...Signaling pathway may be key to understanding roots of hypertension
...use with a genetic inhibition of Gq, the resulting offspring had lower blood pressure. But when the researchers mated the GRK5 mouse with a mouse with a Gq inhibition, the offspring's blood pressure didn't change. "This finding suggests that the overexpression of both proteins leads to different pathways caus......nd found that only a quarter recognised when their offspring were overweight. Where children were obese, a third of mothers and 57% of fathers thought their sons and daughters were "about right". Parents were less likely to recognise overweight boys than girls in the study more than a quarter (27%) of ...