Tag: "oncogenic" at medical news

Other highlights in the September 18 issue of JNCI

...ncer among 1,812 women who had tested positive for oncogenic HPV DNA. Oral contraceptive use and history of live births were not associated with the risk of cervical cancer or its precursor, cervical intraepithelial neoplasia grade 3 (CIN3). However, former and current smokers appeared to have an increased ris...

Human cytomegalovirus may be involved in colorectal cancer

...rcinomas, and virus infection can induce important oncogenic pathways in colon-cancer cells. In view of the many cellular modulatory properties of this virus, our data justify further studies to establish whether human cytomegalovirus participates in pathogenesis of colorectal cancer."...

Other highlights in the September 3 issue of JNCI

...ly, and regress more slowly in women infected with oncogenic types of human papillomavirus (HPV) compared with women infected with a non-oncogenic HPV type or in women with no HPV infection, according to a study by Nicolas F. Schlecht, Eduardo L. Franco, and colleagues at McGill University in Montreal. Cervica...

JCI Table of Contents

...kemias (AMLs) is associated with the appearance of oncogenic fusion proteins generated following specific chromosome translocations. These fusion proteins function as aberrant transcriptional regulators and interfere in the process of myeloid differentiation. The identification and analysis of common and speci...

Vaccine nips breast cancer in the bud

...vaccination with plasmids encoding portions of the oncogenic protein rp185neu and a booster vaccination one week later with cells expressing this protein and also engineered to release IFN-gamma. Of mice that received the combined vaccine, 48% remained tumor free for the duration of the study, a significant im...

2004 Oral Medicine/Pathology Research Award to Gutkind

...8, where he carried out research on the normal and oncogenic functions of non-receptor protein-tyrosine kinases. He subsequently moved to the National Institute of Dental and Craniofacial Research, where he established a new program addressing the molecular basis of cancer by studying normal and aberrant funct...

Encouraging results from vaccine trial to reduce cervical cancer

...Should both girls and boys be vaccinated? How many oncogenic HPV types should the vaccine contain? Is resurgence of oncogenic HPV types not included in the vaccine a real threat? When is booster vaccination required? They conc...

Residual tumor cells are a barrier to targeted cancer therapeutics

...ply a selective pressure to a tumor by blocking an oncogenic pathway, cells escape," says Chodosh. "They find a back door and progress to a more aggressive state that becomes independent of that pathway." Chodosh concludes that the type of genetically engineered mouse models used in these MYC studies yield res...

Three-year cervical cancer screening recommendations may be applicable for certain women with HIV

...cytology (cells) results and who test negative for oncogenic (cancer-associated) human papillomavirus (HPV) DNA...nths for women with normal cytology and detectable oncogenic HPV." Women who are HIV-positive are recommended to have two Pap smears six-months apart after thei...

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