Yale researchers find potential target for treatment and prevention of osteoporosis
...ent mutation increased LRP5 function leading to an opposite phenotype, that is, high bone density," Lifton said. Bone mass increases during childhood and peaks at about the age of 20. It is a major determinant of the risk of osteoporotic fracture. Nearly one million fractures occur annually in people over the...Supportive spouse, family, friends contribute to successful aging
..., she says. There was also a limited effect in the opposite direction. Men and women who reported receiving more demands or criticism from spouses or children tended to have higher allostatic load scores, Seeman and colleagues say. They note that the scores for allostatic load may have been underestimated bec...Light adjustable intraocular lenses may offer customized vision for cataract patients
...hereby consuming all remaining macromers. For the opposite effect -- a reduction in lens power the physician would treat the periphery of the lens instead, driving unreacted macromers to that area. The treatment of astigmatism, a commonly occurring irregularity of the cornea that causes blurred vision, coul...Beta-blockers protect brain during bypass surgery
... "Now, obviously, we are learning that the opposite is indeed true," Newman said. While many heart patients might already be taking beta-blockers in pill form prior to surgery, Newman advocates giving all appropriate bypass patients the drug intravenously during surgery, so that the optimal l...American Thoracic Society Journal news tips for July (first issue)
...w Zealand, Belgium, and German children came tothe opposite conclusion. The investigators felt that prior retrospective results could have beendue to recall bias associated with children who actually had asthma in their first year of life. Fifty youngsters dropped out of the current study before the fifth ye...Breakthrough in hormonal breast cancer therapy
...e risk of cancer recurring in the same breast, the opposite breast, or elsewhere in the body when compared to tamoxifen. This is the first time an AI has been proved to be superior to tamoxifen in early breast cancer. Anastrozole was also associated with a number of important tolerability advantages over t...Viagra helps men with heart failure
... placebo. On the second day, the men received the opposite treatment (sildenafil or placebo) before exercise. Those treated with sildenafil had significantly lower blood pressure and heart rate and improvement in measures of oxygen consumption and carbon dioxide production compared with those on placebo. To...Children with dogs, cats have reduced risk of allergies
... to; as a matter of fact, it was very strongly the opposite of what we expected to find," said Dr. Dennis R. O...target for national averages. "This is exactly the opposite of what we would have predicted from the beginning and it's very significant," Dr. Ownby said. "This...Exercise may not lift spirits of women with eating disorders
...eel-good effects. In fact, it may induce just the opposite feeling. And women in general may get less psychological benefit from exercising than men. Those are among the conclusions presented last month by researchers Jennifer Gerlach and Dorothy Espelage at the American Psychological Association annual con...Brain chemicals can thwart desire to smoke cigarettes
...ior can be manipulated within the same subjects in opposite directions by alternately stimulating and blocking dopamine, which strongly suggests the importance of dopamine in reinforcement from cigarette smoking," notes lead researcher Nicholas H. Caskey, Ph.D., of the Veterans Affairs Greater Los Angeles Hea...Chlorine dioxide gas kills dangerous biological contaminants
... author. The calyx is the apple's bottom, directly opposite from the stem cavity. "We see more and more cases of food-borne diseases associated with fruits and vegetables," Linton said. "Some of this is because we encourage people, especially children and the elderly, to eat more and more of these types of fo...UT Southwestern researchers find clue to understanding tolerance to drugs of abuse
...a decrease in activity in the CREB site causes the opposite reaction. These data suggest the CREB activity in the shell of the nucleus accumbens controls the behavioral responses to emotional stimuli." Barrot said the manipulation of the behavioral responses to the emotional stimuli "appears to be independent...Right side of brain learns language skills after stroke
...ask. However, areas on the right side of the brain opposite the damaged areas on the left did become active during the task, and that activity decreased with practice. Visual areas on the right side also decreased with practice. The team also noticed that patients with smaller lesions had slightly different ...New Parkinson's surgical procedure shows lasting benefits, according to Emory researchers
... subthalamic nucleus helps control movement on the opposite side of the body. Past research has shown that by...uld later be followed by a second procedure on the opposite side. Now these investigators have taken the procedure a step further by lesioning the subthlamic n...Starzl Institute researchers to develop cell-based strategy for tranplant tolerance
... the subtype of dendritic cells apparently has the opposite effect by regulating the immune response and determining that a frontline attack against the organ by T cells is unwarranted. T cells are the soldiers for the immune system that take their cue from other key cells....Teen-age girls, depression, alcoholism, and brain activity
... depression and a family history of alcoholism had opposite effects on the EEG power spectrum. Teen-age girls with a history of depression, not active depression, showed an enhanced amount of eight to 12 cycles per second brain electrical activity. This is referred to as alpha or slow-wave activity. "In ot...Nutrition advice makes heart-healthy diet more satisfying
...heir enjoyment of food, the study authors noted an opposite effect. "Contrary to popular belief, there is no apparent reduction, but rather an improvement, in some measures of quality of life and patient satisfaction with medical nutritional therapy for high cholesterol," say Linda M. Delahanty, M.S., R.D., o...An extra hour of sleep can make a big difference for kids
...ntage of sleep. Reducing sleep by one hour had the opposite effect: It resulted in decreased night-wakings and an increased percentage of sleep, the researchers found. Previous researchers have identified these effects as the bodys way of adapting to sleep loss, but in this study, the sleep-deprived children ...Improved molecular beacons show promise for cancer detection, rapid viral diagnosis
...luorescent dye molecule and a quencher molecule on opposite ends of an oligonucleotide engineered to match specific genetic sequences associated with disease. Initially, the dye and quencher molecules are held close together in a hairpin shape, the quencher preventing fluorescent emission from the dye. Whe...Alcohol-damaged brains 'recruit' new brain regions to perform simple tasks
...erebellum. 'Ipsi' means same side, 'contra' means opposite side. So, we're talking about my contralateral cortex and my ipsilateral cerebellum. The significantly higher activity we found in the alcoholics was on the ipsilateral cortex, the side that we don't normally expect to be activated. This finding i...