Researchers use crippled poliovirus to attack brain cancer
...the IRES from the rhinovirus communicates with the opposite end of the poliovirus genome. That distant region, called the 3-prime non-translated region, drives how the virus transmits its genetic instructions inside the host cell. Gromeier's data suggest that -- in cancer cells -- the rhinovirus IRES and the ...2nd opinion from major center leads to better breast cancer detection, treatment changes
... the ten had a second primary breast cancer in the opposite breast. The ten patients represent 7 percent of the entire study group, giving the consulting radiologists a 7 percent incremental cancer detection rate over the patients' original physicians. In all, 42 percent of recommended biopsies showed malign...Using fMRI technology to understand hyperlexia
...yperlexia, and suggest that hyperlexia is the true opposite of the reading disability dyslexia. Hyperlexia is found in very rare cases in children who are on the "autism spectrum," meaning they display some characteristics of autism. Like autistic children, children with hyperlexia have extreme difficulty...Two proteins may help prevent Alzheimer's brain plaques
...ns would develop even fewer deposits. However, the opposite was true. Moreover, fibrils in animals lacking both proteins developed significantly earlier in life and resulted in the more advanced amyloid plaques. Such extreme Abeta deposition at a young age is akin to that in humans with the rare, genetic form...Study: Muscles respond to getting on your feet after spinal cord injury
...ne leg in therapy can help activate muscles in the opposite leg. "Nobody has been able to show that in humans before," said Ferris, also an assistant professor of biomedical engineering. "It appears there are left-to-right connections in the signal in the spinal cord, not just connections from the brain to th...High cholesterol predicts lower mortality in dialysis patients but is not protective
...than those with lower cholesterol levels, which is opposite of the general public. However, a study by researc... populations such as smokers and the elderly. This opposite association from the expected higher mortality at higher cholesterol has led some physicians to avoi...Cholesterol drugs may lower risk for mental impairment after stroke
...r cognitive impairment-no dementia (VCIND); at the opposite end of the spectrum is vascular dementia, the most severe form of stroke-related brain dysfunction. The prevalence of VCIND is not known but vascular dementia may occur in up to one third of stroke survivors, researchers said. This study focused on...Scientists raise caution about effects of HRT on hearing
...ence of estrogen receptors in the ear. This is the opposite of what we were expecting." The HRT group performed most poorly on a test aimed at measuring not just how well the ear actually detects a sound, but also how well the brain processes that information. A large portion of age-related hearing loss, cal...Study: Carbon dioxide may find new use in producing medical implants
...ecules, this work shows that it can be used in the opposite way," said David Tomasko, associate professor of c...erial became. Lowering the pressure slowly had the opposite effect. Tomasko envisions that such voids within an implant could come in handy for holding extra qu...Single cocaine exposure boosts both drug craving and avoidance
... cocaine injection. The different time courses and opposite behavioral effects indicate the two reactions are carried out through different nerve pathways in the brain, Fields said. The scientists speculate that the KOR avoidance mechanism may be a "compensatory" effect that regulates the addictive power of p...ERI patents treatments for insulin resistance in diabetes accompanying obesity
...gar, while another hormone called glucagon has the opposite effect, prompting cells to release stored glucose into the bloodstream. In healthy individuals the two hormones achieve homeostasis, or balance. Type II diabetes occurs when the body becomes resistant to insulin, preventing it from storing glucose. B...Norepinephrine important in retrieving memories
...ories," says Thomas. Depression may include the opposite problem in that there's often difficulty in memory retrieval, and this could be due, in part, to dysfunction of the adrenergic system. In addition, beta-blockers, which are used to treat heart failure and hypertension (among other ailments) block the...Study finds nerve damage can affect opposite side of body
...previously unknown communication between nerves on opposite sides of the body. In the May 2004 issue of Annal...kin nerve endings in the corresponding area of the opposite limb. The study, released today on the journal's website, may have major implications for the care ...Breast cancer patients with BRCA 1/2 mutations twice as likely to choose double mastectomy
...ble mastectomy to reduce the risk of cancer in the opposite breast, according to the first large-scale study e... greatly elevated risk of developing cancer in the opposite breast as high as 60% by some estimates for at least 10 years following their original diagnosis. ...Breast cancer patients with BRCA1 or 2 mutations twice as likely to have double mastectomy
...inst the development of a new breast cancer in the opposite breast. Although testing was provided free of charge in this study, most insurance companies cover most of the cost for BRCA1/2 testing, says Schwartz, and costs range from $415 for a limited test of three mutations in Jewish women to $2975 for a f...End of life ICU use may require re-evaluation according to University of Pittsburgh study
...hey would prefer a low-tech approach to death, the opposite is happening with more than 20 percent of terminally ill patients dying in intensive care, according to an article in the March issue of Critical Care Medicine, the journal of the Society of Critical Care Medicine. "This is the first study to provide...Other highlights in the April 7 JNCI
...with the receptor status of a breast cancer in the opposite breast for women who do not take tamoxifen, a new ...th breast cancer will develop breast cancer in the opposite breast (called contralateral breast cancer). Tamoxifen reduces the risk of contralateral breast canc...Mothers' cells can cause immunity illness in children
...current study, the Mayo Clinic group looked at the opposite situation: persistence of maternal cells in children. In the Mayo Clinic study, 83 percent of JDM patients had cells from their mother. This compares to 23 percent of their unaffected siblings who had maternal cells, and 17 percent of healthy chi...Malaria: Plasmodium togetherness a strategy for breeding success
...e encounter and binding between two gametocytes of opposite sex, and therefore of enhancing the production of infectious forms and the parasite's reproduction rate. Bound in the human host's peripheral capillaries, male and female gametocytes ingested by a mosquito increase the likelihood of their meeting ins...Cancer gene therapy news backgrounder: New ideas fuel next generation gene therapy research
...ngest surviving gene therapy patient. And, at the opposite end of the spectrum, M. D. Anderson is conducting the world's first gene therapy trial aimed at preventing cancer. Patients at risk of developing oral cancer gargle a concoction twice a week that coats their throats with protective genes. Researchers...