Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
...cing locally advanced and inoperable tumors in the pancreas andstomach. The finding may be an important step ...ow used worldwide. Cancers of the lung,stomach and pancreas often share a genetic mutation, labeled p53, that thwartsstandard chemotherapy and radiation treatme...Polish Dumpling-Like Particle Has Potential In Drug Delivery
...teins such as insulin do. With insulin, which our pancreas secrete to regulate our blood sugar rates, there are two linear polymer chains of amino acids -- the chemical units that are the building blocks of proteins. The linear chains self-assemble into a three-dimensional structure stabilized by linking wi...New "Body-Friendly" Fat Substitute Can Help To Transform
... steady the production of insulin, released by the pancreas in responseto glucose intake, by forming gels that slow the absorption of the glucose fromthe intestine. This could be a significant advantage for patients who alreadychoose fat-free or low-fat foods for weight control, an important factor in the...Encapsulating Insulin-Producing Cells For Possible Diabetes Therapy
...llagenase to dissolve the connective tissue of the pancreas andget out these little clusters that contain 1,000 or so cells, without damagingthem," she said. One problem is that removing islets separates them from the blood supplythat normally keeps them healthy, Hatchell added. "We don't understand h...Intestine Transplant Results Reported At American Society Of Transplantation Meeting
... with the liver; or in combination with the liver, pancreas andstomach. The majority (81 percent) of the patients at the UPMC requiredintestinal transplants because of short-gut syndrome, the loss of more than 70percent of the intestine due to trauma, surgery or disease. For adults,short-gut syndrome may be...Stress, coping and biology intertwine for diabetes control
...sons with Type 2diabetes mellitus. In Type 1 the pancreas loses its ability to produce insulin, resulting inuncontrolled surges in blood sugar. Coma may result, followed by death unlessemergency medical intervention is provided. In Type 2, cell tissues areresistant to the action of insulin, and insulin le...... or radicalpancreaticoduodenectomy (removal of the pancreas head along with an encirclingloop of the duodenum), also known as the Whipple procedure. To assess the role of patient volume and surgical experience onoutcomes, the researchers grouped the 51 hospitals studied into four categoriesbased o...Experimental peptides prevent diabetes and halt its progression
...iabetic, "but werepoised at becoming diabetic. The pancreas was heavily inflamed, the autoimmuneprocess was basically in full gear, the animals were just about to becomeovertly diabetic," Tisch says. "So we were able to show that by immunizing NOD mice at this particularstage with a certain panel of G......ornia to help breathe new lifeinto the whole-organ pancreas transplant program at the University of California...eived benefits. "To date, a functioningwhole-organ pancreas transplant is the only therapy available that can reliablyremove the need for insulin injections in ...New treatment for type 2 diabetes puts insulin back to work
...the function of the insulin-producing cells of the pancreas (beta cells) by 60%. The function of the beta cell...n this 12-month study. (3) In type 2 diabetes, the pancreas attempts to compensate for insulin resistance by producing extra insulin. Years of maintaining high ...Scientists successfully grow insulin-secreting cells to treat diabetes
...treating diabetes is transplantation of either the pancreas or of islet cells which contain beta cells, giving the patient a new source of insulin. Recent advances in these techniques indicate that this is a successful approach, but limited due to the scarcity of donor tissue from cadavers. "Even if you had ...Insulin precursor linked with increased stroke risk; may represent new risk factor
...m of insulin, a chemical substance produced by the pancreas to control the amount of sugar in the blood. "The conversion of proinsulin to insulin occurs in several steps, mainly in the secretory granules in the beta cells of the pancreas, explains Lindahl. "The ratio of proinsulin to insulin in the bloo...Novartis receives FDA approval for Starlix, a new treatment for type 2 diabetes
...cose in the blood. Early insulin secretion by the pancreas is compromised in patients with type 2 diabetes. ..." mode of action on the beta-cell (the cell in the pancreas that produces insulin) that stimulates rapid, short-acting insulin secretion, addressing a basic def...Dual sensor could provide more information, earlier warning for diabetics
...xcess glucose while the pump acts as an artificial pancreas - the organ that produces insulin in the body. Another device known as an insulin detector estimates the amount of the hormone in the blood. Combining two types of sensors in such a small device was a complicated task, Wang said. Glucose is measured ...New procedure makes kidney transplant an option for thousands on waiting list
... says Mark Stegall, M.D., a Mayo Clinic kidney and pancreas transplantation surgeon. "It was very unlikely they would ever get a transplant." Dialysis works like an artificial kidney. It prolongs life but it is not ideal. Three times a week for four hours at a stretch, patients hook up to a machine that remo...Newer form of 'gold standard' drug helps kidney transplant patients do better in long term
...n 13,000 people receive a new kidney or kidney and pancreas each year. A similar drug, tacrolimus, or FK506, also became available to patients during the same time period. Since then, generic versions of reformulated cyclosporine have come on the market. Meanwhile, another medication, mycophenolate mofetil, o......normal insulin. The insulin secreting cells of the pancreas are unable to compensate by making more of the hormone. In healthy individuals, insulin triggers a series of events that allows certain cells to take in sugar, in the form of glucose, from blood. High glucose levels, in turn, can lead to cardiovascul...Intensive exercise improves body's ability to process blood sugars
...fasts. Insulin, a hormone that is secreted by the pancreas after eating, is responsible for the regulation of glucose levels in the blood; excessive amounts of insulin can, over time, lead to the complications associated with diabetes and heart disease. "Insulin sensitivity, or its ability to stimulate gluco...Many obese youth have condition that precedes type 2 diabetes
...y. Eventually, the insulin-producing cells of the pancreas cannot keep up with the body's increasing demand for insulin, glucose builds up in the blood, and type 2 diabetes begins. "The epidemic of childhood obesity in the United States has been accompanied by a marked increase in the frequency of type 2 d...Drug cocktail prevents hepatitis B virus from recurring after liver transplant
...A professor and chief of the division of liver and pancreas transplantation, and director of the Dumont-UCLA Liver Transplant Center. This is truly remarkable since as recently as five years ago patients with hepatitis B were not even being considered for transplantation. Approximately 1.25 million people i...