Knock out blood protein drug signals possible new treatment for Alzheimer's and diabetes
...sociated with Alzheimer's disease and those in the pancreas with type 2 diabetes. The research team, based at the UCL Centre for Amyloidosis and Acute Phase Proteins at the Royal Free Hospital, first showed that SAP from the blood contributes to amyloid deposition by sticking to amyloid fibres. They then set...Early intervention stops damage to insulin-producing cells
...s grow resistant to insulin, the beta cells in the pancreas shift into overdrive to produce more insulin to compensate. Over time, this high workload causes beta cells to wear out in some people and produce less insulin, or stop altogether, causing type 2 diabetes. Buchanan and colleagues believe that lesseni...CWRU/University Hospitals of Cleveland researchers investigate new cancer treatment
...ative to tumor resection for cancers in the liver, pancreas and prostate. Our new device is designed to work in synergy with image-guided thermal ablation and looks to offer a bright new combination therapy." Gao, Haaga and their research team are establishing a rational approach for the design of the dual-re...Common diabetes drug causes arteries to spasm, endangering heart
...ates. These drugs stimulate the beta cells of the pancreas to squeeze out more insulin and also make insulin ...ed by the sulfonylureas. Sulfonylureas induce the pancreas to release insulin by blocking this receptor. Blocking the receptor inhibits a potassium channel on...More than 10 million developed cancer in 2000
...s of the oral cavity, pharynx, larynx, oesophagus, pancreas and bladder. In a recent consensus conference at the International Agency for Research on Cancer in Lyon (World Health Organization), this list was extended to include several organs with a two- to three-fold elevated risk in smokers versus non-smoke...Researchers warn antipsychotic drug
...of necrotizing pancreatitis, a condition where the pancreas breaks down and dies. Most cases (71 percent) occurred within six months of starting the drug and many cases were associated with moderate weight gain. "The average age of adults showing signs of diabetes after taking olanzapine was about 10 years yo...Hormone prompts adult stem cells to differentiate into islet cells
... important because, in diabetes, beta cells in the pancreas have a limited if any capacity to proliferate, and...destruction of insulin-producing beta cells of the pancreas in a mistaken attack by the body?s immune system. As a result, patients do not produce the insulin ...Lombardi Cancer Center to enroll current and former smokers in nationwide clinical trial
...e than cancers of the breast, prostate, colon, and pancreas combined, and it will claim nearly 155,000 lives this year--300 of them in the District of Columbia alone," said Edward P. Gelmann, MD, professor of medicine and oncology and the principal investigator of NLST at Lombardi. "Our hope is that this stud...UCLA seeks thousands of current and former smokers for landmark lung cancer screening trial
...ricans every year than breast, prostate, colon and pancreas cancers combined, and is responsible for about 28 percent of all cancer deaths in the United States. This year alone, more than 169,000 Americans will be diagnosed with lung cancer. Of those, 154,900 will die, according to the American Cancer Society......e than cancers of the breast, prostate, colon, and pancreas combined and will claim nearly 155,000 lives this year. Our hope is that this study will lead to saving lives." To help ensure that NLST reaches full enrollment quickly, the American Cancer Society will support NCI with targeted promotional and outr...New clues to help diabetes and hypoglycemia
... relatively constant level of blood glucose by the pancreas constantly adjusting the amount of insulin it releases. A diabetes, blood sugar can only be controlled by injections of insulin. This causes a series of highs and lows in blood glucose. The problem with such an intensive program of insulin injecti...Researchers find trigger for devastating digestive disease, propose treatment
...l cancer. In the small intestine, enzymes from the pancreas initially digest gluten by breaking it into a number of fragments called peptides. In most people, the larger peptides probably work their way down to the lower intestine where they are eaten by microorganisms. "But in people with celiac sprue, the...Doppler-guided fluid administration during surgery improves outcome
...cardiac surgeries of the prostate, colon, bladder, pancreas and liver as well as major gynecologic procedures. In these surgeries, physicians anticipated blood losses of at least 500 ml. Fifty patients had their fluid levels guided by EDM, while the other 50 received standard care. For the EDM group, the rese...UF researchers report: Immunosuppressant drug prevents late rejection of transplanted kidneys
...id Kaplan, also medical director of the kidney and pancreas transplant program at the UF Shands Transplant Center. "Physicians have yet to pinpoint its precise cause, and there is no known treatment for this type of injury. Acute rejection appears to be linked to that. People with acute rejection have a highe......xternal stimuli. For example, a "smart" artificial pancreas might release insulin inside the body in response to high sugar levels. Other applications may include exotic foods, cosmetics or sensors. But scientists need to better understand the molecular behavior of the gels before they can optimize them for s...Organ transplant recipients face serious kidney-failure risk, study finds
...ed transplants of any solid organ except kidney or pancreas between 1990 and 2000. But in the largest-ever stu...ll the patients who had never received a kidney or pancreas transplant before they received their heart, lung, liver, intestine or combination heart-lung transp...University of Pittsburgh intestine transplant results reported at international meeting
...which include the small intestine, liver, stomach, pancreas and duodenum, were performed in 25 adults and 12 children, and modified multivisceral transplants without the liver were performed in nine adults and four children. "The shortage of organs remains a limiting factor to successful intestine transplant...On the horizon of glucose monitoring: A review
...uced by the body. Insulin is a hormone made by the pancreas to regulate the amount of sugar in the blood. High levels of glucose in the blood can seriously affect other body systems, particularly over time. The most common and, to date, the most inexpensive way to monitor blood glucose is by piercing the fing...First steps towards a vaccine for pancreatic cancer
... two years. The typical survival after surgery for pancreas cancer is 14-15 months. However, Dr Maki warned th...g process. Dr Maki said: "The problem is that the pancreas makes digestive enzymes that destroy proteins . . . in other words, the pancreatic tumour cells them...Joslin and Beth Israel Deaconess Medical Center sign new joint venture clinical agreement
...ations of diabetes (i.e. heart disease, kidney and pancreas dysfunction, obesity, neuropathy, vascular complic...ease; eye care for those with diabetes; kidney and pancreas transplantation as well as clinical trials of islet cell transplantation; high-risk pregnancy; and o...