Genetic test for cell-proliferation enzyme could improve treatment of acute lymphoblastic leukaemia
...on could identify patients at an increased risk of poor outcome from acute lymphoblastic leukaemia. The enzyme thymidylate synthase is associated with cell proliferation, and is therefore an important target for anticancer drugs, including the chemotherapeutic agent methotrexate. Maja Krajinovic from th...Early breast cancer tends to be more aggressive in women from deprived backgrounds
... poorer outcome in the long run. Other illnesses, poor diet, smoking and environmental factors may also play a role in determining how well a woman responds to treatment....Biopsies of the internal mammary sentinel nodes may improve patients chances of survival
...ncer patients. These findings are associated with poor prognosis, as we know from investigations in the 1950s and 1960s when the same percentage (25%) of IM metastases was found, using extensive and mutilating surgical procedures. Thus, IM-SN biopsy, while using a minimally invasive technique, provides ...From sci-fi to reality microendoscopy to diagnose breast cancer?
...pes less than 1 mm across - ideal in size but with poor picture quality because they contain very few glass fibres. So the Guys team, working with endoscope designers and manufacturers Acueity Inc. from California, enlisted ideas from Hollywood film technicians (who use a single glass rod to transmit an i...Guidelines lacking for patients hospitalized for heart failure
...lly. Hospitalization usually is associated with a poor prognosis, high hospital readmission rates and death within 30 to 60 days after discharge. In this patient population, placebo-control, randomized clinical studies, the "gold standard of medicine" from which evidence-based management guidelines n...People suffering from epilepsy continue to lack a good quality of life
... people with hard to control epilepsy experience a poor quality of life, but that many do not proactively pursue new treatments that could help. The Quality of Life in Epilepsy survey, sponsored by Cyberonics, reveals that people with epilepsy are three times more likely to be unemployed than the nationa...UCLA study shows contracting HIV can serve as an opportunity for positive change and growth
...ere already burdened with the problems of poverty, poor housing, inadequate employment opportunities and other day-to-day stressors, Taylor said. Clearly, these women understand the problems in their lives, but they nevertheless see their infections as an opportunity for growth and change. If finding some...Low socioeconomic status may influence quality of breast cancer treatment
...insured by Medicaid. The authors conclude that, poor persons, regardless of their race, are likely to have undesirable cancer outcomes. This finding should challenge the research and policy communities to provide remedies for reducing these disparities. In an editorial, Otis Brawley, M.D., of the Wins...Hormone replacement therapy may be associated with increased ovarian cancer risk
...especially given the prevalence of HRT use and the poor prognosis of epithelial ovarian cancer....Researchers link stroke patients' anger and aggression to brain injury
...) I feel infuriated when I do a good job and get a poor evaluation. * Patients used a 1-4 scale, with 4 representing "almost always" to describe their prestroke and poststroke feelings of anger....Patients needlessly suffering from chemotherapy induced nausea and vomiting
...ation of anti-emetics significantly contributes to poor CINV control, another key issue is a lack of relevant nurse training. In addition, a low level of awareness of the issue and cultural influences may also be a contributory factor" he concluded. Trained oncology nurses have a significant influence ov...Exploring the brain chemistry of people at risk for alcohol disorders
...sorder, hyperactive tendencies, rule breaking, and poor response to discipline. Adult COAs tend to exhibit poor impulse control, antisocial tendencies and sensation seeking. A new study has found that young adult...Annals of Internal Medicine tip sheet, April 16, 2002
...ers found that 18 percent of diabetic patients had poor control of blood sugar, 34 percent had high blood pressure, and 58 percent had high cholesterol. Preventing Partner Violence Better Than Just Treating the Victims Treating the victim has been the primary response to violence against intimate partne...At 2 years, cocaine babies suffer cognitive development effects
..., and mental health services for women especially poor women who are currently underserved, Singer said....Evidence does not support psychological treatments for epilepsy
...of these treatments. Some of the studies were of poor methodological quality, while others were contradictory in their results, notes study author Sridharan Ramaratnam, MD. We found some promising indications regarding reduced anxiety, improved medication compliance and social competency, and even in s...Lack of awareness of acute stroke symptoms and treatment
...r acute stroke victims may be underutilized due to poor recognition of stroke symptoms and inadequate knowledge of acute treatment options. This conclusion emphasizes the need for more structured stroke education and prevention programs for persons at high risk, according to a study presented today at th...Junior doctors need training to reduce prescribing errors
...escribing errors in hospitals are a consequence of poor understanding of drug prescribing. Authors of the study conclude that junior doctors should be trained in the principles of drug dosing, and that medical staff should promote a working culture which recognises the importance of prescription writing. ...Urgent action needed to improve maternal care in Latin America
...in maternal care. The first study shows that many poor women in Brazil actively seek a caesarean section because of fear of substandard labour care, including lack of pain control. Rich women were more likely to have caesarean sections, and a vaginal birth was considered a risky and negative experience....Clinical depression may have negative effect on periodontal treatment
...ely to continue to smoke, which has been linked to poor response to periodontal therapy," said Elter. "Mos...has found that depression has been associated with poor outcomes from cardiac surgery and reconstructive spinal surgery. In this study, the presence of pre...UCSF scientists may have found link to early childhood tooth decay
...e to lack of dental health care in underserved and poor communities, the study found. ECC is five times more common than asthma and seven times more common than hay fever, but researchers are just beginning to understand its complexity. In the UCSF study, researchers assessed salivary levels of the bacte...