DNA Imaging to Design Better Drugs
...ject. "Now when a medicinal chemist synthesizes a potential drug, we canvery quickly tell them if it binds to DNA, how tightly it binds, and themode by which it binds," he added. One of the major advantages of the new assay is it shows researchershow drugs affect single DNA molecules, said Dr. Lawrence Botto...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...ry systems used to treat serious pain and may be a potential technique for the management of drug addiction. The button-sized polymer works much like the continuous-release birth control implant. It will be inserted under the skin through a tiny incision made under mild, local anesthetic. The polymer contai......IDS may largely be explained by differences in the potential of (certain) HIV strains (with particular affinity to the thymus and which can cross the placenta during gestation) to cause early thymic disruption... "In addition to their pathogenetic importance, our findings have clinical implications that includ...Routine Dental X-ray May Be A Valuable Tool In Stroke Prevention
...is study." Carter decided to investigate the potential of using a type of dental X-ray called a screening panoramic radiograph to detect carotid calcification after reading a journal article from 1981 that reported such a possibility. A panoramic radiograph is a wide-angle frontal X-ray taken during a p......n, and insurance companies coulduse it to identify potential landslide or fire-risk areas." Barnes chose to test the system first on mammograms because breastcancer is a serious health threat. The <AHREF="http://www.cancer.org/">American Cancer Society estimates thatin 1997 some 180,200 new cases of ...New Drug For Parkinson's Disease Proves Effective, Study Finds
...ians aretrained to design and interpret studies of potential newtreatments to neurodegenerative diseases....Milk Extract May Heal Wounds And Smooth Wrinkles
... healing powers. Dr Belford says the world market potential for such a healing stimulantis enormous, perhaps as much as $10-20 billion. If the whey extract provessuccessful, he says, it will be the only substance of its kind in the world. "There's nothing on the market which actually stimulates wound repair,...Psychiatric Symptoms May Signal Brain Damage From Diet Pills
...nt, according to McCann. "However, the neurotoxic potential of fenfluramines in humans has not been systematically evaluated," write the researchers. Moreover, "the functional consequences of brain serotonin neurotoxicity are largely unknown," even though the neurotransmitter is thought to be important "in ...Many Medical Screening Tests May Be Unnecessary.
...evelops a disease. The article describes several potential risks of screening tests with controversial benefi...ecisions. "For most diseases for which there is a potential screening test, the effectiveness of screening is controversial," the article says. "Physicians can...Affordable, Hand-Held Biosensor For Diagnostics
...sequences to its complementary strand, suggestinga potential role for a variety of genetic studies and tests, including DNAfingerprinting for clinical and forensic applications. Another biosensor provedsensitive to the binding of certain antibodies, manufactured by the body'simmune system, to small amounts of ...Jefferson Researcher Finds New Digital X-Ray Technology May Cut Costs And Improve Patient Care
...Hospital, and to be unveiled next week, has the potential to replace the current film X-ray technology, while reducing health care costs and improving patient care, says Gary S. Shaber, M.D., research professor of Radiology, Jefferson Medical College, Philadelphia, and director, Division of Gene...Physicians' Opinions Influenced By Drug Industry
...lists can determine for themselves if there is any potential bias inan author's position," says Detsky. "Editor...d to be morespecific in their determination of any potential bias when requesting editorialmaterial," he adds, suggesting editors provide potential authors a que...Penn Researchers Initiate Ground-Breaking New Trials To Treat
...ed new treatment protocols which, inturn, have the potential to extend the lives of patients andimprove their q...or cancer treatment. "Photodynamictherapy has the potential capability to selectively eliminatecancerous cells using light and photosensitizers," states Dr.Hahn...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
...lar relationship exists in humans. Another potential hide-out created by Pgp may be in some of the CD4c...th Pgp. "This work is exciting because the potential of Pgp as a factor in drugabsorption and tissue penetration has not been previously appreciated," Ki...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...perspectives, and our access to this expertise and potential productopportunities provides significant value to our company." Said Michael Colvin, M.D., Director of the Duke Comprehensive Cancer Center, "The last few years have witnessed enormous advances in basic cancer biology and the understanding o...Should Drugs Be Used In The Treatment Of Obesity: A Point-Counterpoint Discussion
...er the benefitof anti-obesity drugs outweigh their potential medical risks.Bray argues that even modest drug induced weight loss reducesobesity complications (hypertension, coronary disease,diabetes), while Hirsch argues for a moratorium until drugscan be better targeted to specific causes of obesity yet tobe ...Chemists Closing In On Commercial Potential Of Alkanes
...LEY, CA -- The elusive goal of harnessing the vast potential of one ofthe earth's most plentiful materials is another step closer to realization.Using ultrafast spectroscopic techniques that provide "stop-action" imageswithin a trillionth of a second, scientists at the U.S. Deparment of Energy'sLawrence Berke...Chemist Turns To Self-Assembly To Create New Drugs
...ed a new way offorming a nearly endless variety of potential drugs, thenplucking out the most promising candida...ffer afaster way for chemists to create and screen potential newdrugs. "The approach shows great promise because it's fundamentallymore efficient," says Pau..."Powerful New Tool" For AIDS Is Reported In Science
...technique at the earliest time. We anticipate that potential beneficiaries will include AIDS, cancer, osteoporosis, heart patients and others." "The implications of the technology's capability to quickly and accurately monitor the status and progress of this disease in real time are significant", said Joseph...New Math, High-Tech Imaging Solving Old Riddle: How Does The Brain Operate When We Think?
...and oxygen use in differentorgans. fMRInow has the potential to become much more like a routine blood test that letsdoctors diagnosediseases by comparing levels of substances in the blood with normal ranges." The type of fMRI the team used shows changes in brain activity due toincreases ordecreases in o...