Tag: "precursor" at medical news

Cancer Protection Compound Abundant In Broccoli Sprouts

...gh levels of glucoraphanin, thenaturally-occurring precursor ofsulforaphane. However, tests reported in the new study showed that glucoraphanin levelswere highlyvariable in broccoli samples, and there was no way to tell which broccoli plantshad the mostwithout sophisticated chemical analysis. "Even ...

Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack Risk Reduced By 47% With Use Of Tirofiban

...locking the aggregation of platelets -- which is a precursor to clotdevelopment." In their two-year investigation of 1,915 patients with unstable anginaor non-Q-wave myocardial infarction (which represents the middle ground,clinically speaking, between angina and a full-blown heart attack), theresearch...

ALA/ATS Meeting Explores Gender Differences In Smoking And Lung Transplant Outcomes And Heart Attack Risk From Asthma Medication

...th also could becaused by angina, which could be a precursor to a heart attack. "Physiciansshould consider other diagnoses in patients presenting with shortness of breath,especially those with history of heart disease," Dr. Au said. Beta-agonists are bronchodilators, drugs that open up the airpassa...

Postmenopausal hormone replacement therapy linked to increased risk for certain types of rarely occurring breast cancer

...explain this observationsince these tumors are not precursor lesions for other types of invasive breastcancers. The authors agreed that further study is needed and that this researchshould explore more fully differences in the association between types ofpostmenopausal hormone use and breast cancer ris...

Keck Foundation funds research to repair the injured spinal cord

...ore ways to enhance the survival andfunctioning of precursor cell transplants. Twelve faculty members will conduct four studies. Two studies will focus onprocesses that would sabotage spinal cord transplants if precautionary measureswere not taken. Choi will study excitotoxicity, a process that quickly killsn...

Scientific societies honor creation of the Mexican steroid hormone industry

...de bajo costo, eventualmente llegó a ser el precursor preferido en la preparación industrial de cortisona, la hormona anti-inflamatoria. En 1951 los investigadores de Syntex sintetizaron el primer contraceptivo de uso oral a partir del material inicial de Marker. Así, Syntex y sus compet...

Study links one human gene to multiple diseases of old age

...l age-related diseases. These proteins include the precursor of the beta-amyloid peptide, the main component of plaques found in the brains of Alzheimer's patients. These plaques form after beta-amyloid is modified by an enzyme called transglutaminase, which Roninson and his colleagues found was also stimulate...

Protease inhibitor could help prevent alzheimer's

...sentially cuts the larger protein known as amyloid precursor protein (APP) in half and prevents it from affecting other brain cells. "The production of (beta-amyloid) to cause Alzheimer's disease is a mistake in the cell," Tang said. "If we can prevent the cell from making this mistake, then we can stop the ...

Purdue 'stealth compounds' attack cancer cells

...embrane." Many current therapies instead deliver precursor compounds that the cell then uses to "build" nucle... a time-consuming process to form nucleotides from precursor compounds, called nucleosides. "The problem with using nucleosides is that viruses and cancers get...

ORNL sees increase in sales of radioisotope to fight cancer

...dioisotopes declined. Demand for actinium-225, the precursor for bismuth-213, rose 34 percent in fiscal year 2000, from 243 millicuries (mCi) in 1999 to 326 mCi in 2000. Bismuth-213 shows great promise for treating acute myeloid leukemia, lung cancer and large tumors. Revenue for actinium-225 was $151,033 comp...

MetaPhore Pharmaceuticals initiates Phase I clinical trial of enzyme mimetic compound for oncology

...e compound in normal, healthy human subjects, as a precursor to Phase II trials in which M40403 will be tested as a co-therapy with interleukin-2 (IL-2) for advanced skin and end-stage kidney cancers. This study is the first human clinical trial for MetaPhore and the companys proprietary family of enzyme mime...

University of Pittsburgh research uncovers new mechanism that may be the cause of mild cognitive impairment

...ngly common memory problem that is thought to be a precursor to Alzheimers disease (AD). The results are surprising even to the researchers conducting the study and may explain why current medications dont improve memory function effectively. Further, the findings may redirect research into many of the newer t...

New medical system for colon cancer screening

...table procedure for screening of colon polyps, the precursor of cancer. In contrast, conventional colonoscopy is invasive with a risk of puncturing the colon and requires that the patient be sedated. The negative perception of this method and the reluctance of the general public to get screened play a major ro...

Filatov Eye Institute contests validity of recent study

...v found that a majority of patients who had PRK (a precursor of LASIK) also experienced night vision problems. However, when he repeated the study prospectively, Dr. Filatov found that most of the patients who had night vision problems after surgery also had these problems prior to surgery. Not surprisingly,...

Mayo Clinic study defines patients at greater risk for developing multiple myeloma and related bone marrow cancers

...are considered to have MGUS, a condition that is a precursor to multiple myeloma or related cancers. MGUS is pr...a, research on MGUS is important because it is the precursor condition to the more serious malignancy of myeloma, says Dr. Kyle. Multiple myeloma is a cancer of ...

Cholesterol bad for brain too, UCSF study says

...hey increase the risk of cognitive impairment, the precursor to Alzheimers disease, according to a study of elderly women by UCSF researchers. Also, women who used cholesterol-lowering drugs called statins scored higher on tests of basic cognitive skills, such as memory, attention, and language, according t...

Novel anti-coagulant clears hurdle

...ls. When Factor Xa is activated, it converts a precursor chemical circulating in the blood known as prothrombin into the enzyme thrombin. Once activated, thrombin then converts circulating fibrinogen (Factor I) into the protein fibrin, the primary building block of a blood clot. The advantages of interrupt...

UCSD team reviews pituitary gland development, from a common primordium to distinct cell types

... direct the series of developmental steps by which precursor cells gain a pituitary identity, proliferate, and differentiate to form the distinct hormone-producing cell types of the mature gland, Scully says. In their Science review article, the researchers describe an initial external signaling phase where ce...

Long-term use of oral contraceptives could increase risk of cervical cancer for women with HPV

...studies of patients with carcinoma in situ (ISC [a precursor of ICC]). Information about use of oral contraceptives was obtained from personal interviews. Data were available for around 1900 women from Thailand, the Philippines, Morocco, Brazil, Peru, Paraguay, Colombia, and Spain. 94% of women with ICC, 72% ...

Buck Institute researcher identifies new drug targets for Alzheimers disease

...ajor pathway for beta-site cleavage of the amyloid precursor protein. These new results suggest the very impor...reached an understanding of how the normal amyloid precursor protein (APP) in the brain is cut by secretases into smaller toxic peptides that destroy critical br...

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