Cord blood cells proven to differentiate into heart muscle and brain cells
...and illuminate proteins unique to oligodendrocytes precursor cells. Similarly, she stained the cells with antibodies for a host of other cell types. The presence of unique proteins in a given cell confirms that it is actively producing that protein, not just that its genetic code is capable of doing so, said H...Blood test could avoid inappropriate use of antibiotics for respiratory infections (pp 600)
...ublic health. Blood concentrations of a calcitonin precursor protein known as procalcitonin are substantially raised during acute bacterial infection. Beat Mller from University Hospital Basel, Switzerland, and colleagues assessed the effectiveness of a sensitive blood test to identify procalcitonin concentrat...Study moves in on why astronauts suffer bone loss
...are relieved of the burden of bearing weight, bone precursor cells fail to respond to insulin-like growth facto...e trial period, the team found that the numbers of precursor bone cells in the forelimbs of rats that had received IGF-1 was double that of rats that had not rec...An alternative to bone-marrow donation
...S cell lines to develop into bone-marrow and blood precursor cells in culture. They also devised a method to select the best cells from these cultures. Injection of the selected cells into the bone marrow of mice that had been depleted of their own bone-marrow cells resulted in restoration of blood cells, incl...Embryonic stem cells induced to develop into bone marrow and blood cells
...rs to induce stem cells in culture to develop into precursor bone marrow and blood cells. They also developed a technique to select the most viable cells for injection. Despite the genetic mismatch between donor and recipient mice, the injected cells were not rejected. The injected cells matured into a new im...Fatty acid pathway, glucose combine to produce triacetic acid lactone
...B) to use glucose to make TAL. TAL is an energetic precursor for TATB, an explosive much more stable and sensitive than TNT. Subsequently, Zha said, TAL can be chemically changed to phloroglucinol, a pivotal structure necessary for the synthesis of a variety of bioactive and energetic compounds. FAS-B is a pri...Calorie restriction drastically reduces risk of heart attack, stroke and diabetes
...sk of developing diabetes or clogged arteries, the precursor to a heart attack or stroke. In fact, according to researchers at Washington University School of Medicine in St Louis, some risk factors were so low they were comparable to those of people decades younger. The study, led by John O. Holloszy, M.D., ...Research news from Tufts University, Friedman School of Nutrition Science and Policy: May 2004
...) of pureed carrots absorbed less beta carotene (a precursor to vitamin A) than the researchers previously thought. Previously, the conversion factor for beta carotene was 12 micrograms for one retinol activity equivalent. In this study, Tang and colleagues found that this number increased to 15 micrograms of ...OHSU researchers uncover genes involved in early stages of Alzheimer's disease
...tudied mice that overexpress human mutated amyloid precursor protein. These genetically-altered mice produce heightened levels of amyloid precursor protein. Over time, higher than normal levels of this protein can result in structures in the brain ...Red palm oil as a means of combating vitamin A deficiency
...ary consumption of this vegetable oil, rich in the precursor of vitamin A, beta-carotene, in reducing deficienc... This oil, known for its richness in the vitamin-A precursor beta-carotene and its high efficiency, is, however, commonly produced and used in another area of Bu...Dental pulp cells may hold key to treatment of Parkinson's disease
...the cells. The cell mixture then contains neuronal precursor cells and cells that produce beneficial neurotrophic factors. Nosrat emphasized that there is much work to be done before human patients might find relief from Parkinson's symptoms as a result of this therapy. It is still many years from being teste...Researchers define mechanism that enables stem cells to track migrating brain tumor cells
...4 as a key element governing the process of neural precursor migration toward glioma cells may allow for more efficient isolation of potential tumor-tracking cells, which may hasten the therapeutic testing of glioma-tracking neural precursors in the clinical setting," said Dr. Black, who holds the Ruth and Law...Could skin cells become brain cells?
...ET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the f...gues used skin cells from adults to generate nerve precursor cells. They did this by a two step process involving soluble agents called growth factors which gene...Isolated soy protein shown to benefit type 2 diabetics, study indicates
...s the elevated level of serum arginine, a chemical precursor to nitrogen oxide that dilates arteries, that was observed in the men. Arginine may improve blood flow in the kidney, he said. The study, despite focusing on just 14 participants, "is probably the strongest one done so far from the numbers of subjec...News tips from the Journal of Neuroscience
... of the results of proteolytic cleavage of amyloid precursor protein (APP). Cleavage by beta- and gamma-secretase leads to A-beta production, whereas alpha-secretase cleavage results in a soluble form, sAPP-alpha. This week, Stein et al. examine the apparent neuroprotective role of sAPP-alpha in mice. Using an...How a dietary supplement can protect against Alzheimer's disease
...ered to have the human version of a mutant amyloid precursor protein (APP)--the source of the brain-clogging protein in Alzheimer's disease. The researchers' analyses revealed that such animals showed particular vulnerability to damage to structural proteins that make up the "receiving stations"--called dendri...Proinflammatory mononuclear cells in obese found to contribute to diabetes, heart disease
...e pointing to chronic cellular inflammation as the precursor of heart disease and diabetes. In research published in the Sept 21 issue of Circulation, the researchers show for the first time that circulating mononuclear cells -- the body's monocytes (the largest type of white blood cell) and lymphocytes -- ex...U-M team treating mouth wounds by engineering tissue grafts
...ients to demonstrate proof of concept. That is the precursor to moving into the trials that inform an FDA decision to approve a new medical treatment. Following successful completion of the preliminary studies, Feinberg plans to seek FDA approval for a larger clinical trial involving 50 patients. Fei...Global air pollution map produced by Envisat's SCIAMACHY
... on ESA's ERS-2. However GOME was only a sub-scale precursor of the German, Dutch and Belgian financed SCIAMACHY flying on Envisat. While both instruments function in the same way, GOME has a limited spatial resolution of only 320 x 40 km, compared to a typical 60 x 30 km with SCIAMACHY, which also observes t...New way of controlling cholesterol may help treat Alzheimer's
...e secretases" enzymes that cut the larger amyloid precursor protein into smaller fragments, including amyloid-beta. "Because secretases have normal functions, secretase inhibitors have to be tailored to selectively stop amyloid-beta production. Since they do not affect secretases, ACAT inhibitors may have f...