Scientists Produce New Anti-Malarial Compound
...sive and impractical. The Hopkins researchers have previously developed syntheticversions, or analogs, of artemisinin; the synthetic drugs havebeen shown to cure malaria in monkeys. The new compounds,however, would be easier and less expensive to produce than thoseanalogs of artemisinin. A scientific paper abou...Fertilization Protein Structure To AID in Leukemia Treatment
...by the National Science Foundation, has revealed a previously unknown relationship between a protein in the eggs of a marine mollusk and a protein on the outside of human white blood cells. The work is published in the November issue of Nature Structural Biology. The egg protein is from the Califor...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...contribution to ligand binding than scientists had previously imagined,"he added. To prove their conjectur...nding of aligand to a much greater extent than was previously imagined. The bindingsite becomes "much more hydrophobic than you would have guessed,"he said. ...New Test May Improve Treatment Of Kidney Disease
...itional patients hasshown that somepatients -- who previously had not been helped much by medication -- haveresponded quickly tomedications found effective in the assays. Others have been helped by a lowerdose of medication thanpreviously thought necessary. More investigation still needs to be done on thi...NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
... associated receptors." Whereas scientists previously believed these receptors used a differenttype of s...messaging system has given researchersinsight into previously unknown signaling pathways for the entire class ofreceptors, which include those for a variety of cr...Some Good News In Treating Infection Common To HIV Patients
...desensitization of a vast majority of the patients previously allergic to Bactrim. "It's quite important," he says, "because we can now avoid having to give multiple medications, which avoids toxicity of drug interactions and it's much less costly." The most common alternate method of preventing pneumocystis ca...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
...drugabsorption and tissue penetration has not been previously appreciated," Kimsaid. "We need to find out in humans how active this transporter is and whetherwe can inhibit its activity. "HIV probably has multiple ways to hide out, and the one we'resuggesting is that Pgp protects it from drug exposure. ...Study Finds Incidence Of Stroke Over 40 Percent Higher Than Previously Stated Figures
...nt magnitude of stroke issignificantly higher than previously thought," says Michael D. Walker, M.D.,Director of the Division of Stroke, Trauma and Neurodegenerative Diseases at theNational Institute of Neurological Disorders and Stroke (NINDS). "With theadvent of new and effective treatments for acute stroke,...Heart Attack Survivors Can Lower Stroke Risk By Taking Cholesterol-Lowering Drug, Study Says
...e risk of a stroke orministroke in people who have previously suffered a heart attack. An analysis of the Cholesterol and Recurrent Events (CARE) study found a32 percent reduction in strokes and a 27 percent reduction in either strokes ortransient ischemic attacks (TIAs) -- "miniature" strokes, which ......atwere different and less severe than any reported previously in the medicalliterature. The disorder, termed delayed pulmonary toxicity syndrome (DPTS) bythe Duke researchers, can be successfully treated by inexpensive corticosteroids(prednisone) if diagnosed early in the course of a woman's cancer treatment. ...First Trimester Screening For Down Syndrome Possible, NICHD-Funded Study Finds
...y-associated protein A. Smaller studies conducted previously have shownthat both hCG levels and levels of the beta subunit of hCG are higher in thepresence of a fetus with Down syndrome than in a fetus with a normal chromosomecount. Conversely, blood levels of protein A are lower than normal in thepresence of...Procter & Gamble Supports Yale University Collaboration For Public Health Training Throughout China
...or Yale students inpublic health, said Merson, who previously headed global programs for the WorldHealth Organization on diarrheal diseases, acute respiratory infections andAIDS. The proposed internship topics for the first year are a study on smokingand mortality in China; an AIDS prevention project; a survey...Widely Used Therapy May Not Be Effective In Treatment Of Acute Stroke
...to prevent recurrent stroke may not be as great as previously thought. "Physicians need to reconsider when they should use heparin," says John Marler,M.D., a neurologist in the Division of Stroke, Trauma, and NeurodegenerativeDisorders at the NINDS, "especially considering the availability of other acutestroke ...PITT Researchers Demonstrate Human Brain's Natural Mechanism For Guarding Against Errors
... incorrect responses, areaction that had been seen previously in studies of brain electrical activityand attributed to the ACC. However, they also found that there was increasedACC activity during correct responses on trials where!! response competition occurred. This leads them to believe that the primarycon...Health Risk To "Cigarette Babies" Is Neglected, Duke Scientist Charges
...ue to cigarettesmoking. "For example, many previously believed that crack cocaine caused SIDS,but when investigators began to look at the incidence of SIDS in the offspringof women who used crack cocaine, they found it to be no higher than in theoffspring of women who smoke cigarettes. So cocaine itself...ACE-Inhibitors Score High In Reducing Heart Attack Deaths
...s per1,000.Other high-risk groups -- those who had previously had a heart attack and thosewith diabetes or high blood pressure -- benefited more from ACE-inhibitortreatment. In addition, the drug therapy reduced the rate of heart failure -- a major causeof heart attack disability -- by six cases per 1,000 in th...Educational Intervention Can Reduce Sexual Behaviors Known To Transmit HIV
...ost were single and unemployed and had beentreated previously for STDs, and all were engaging in behaviors that put them athigh risk for HIV. Most participants reported primarily heterosexual behavior,although 7 percent of male participants reported having sex with men during thethree months prior to the baseli...World's First Producer To Repair Brain Damage From Stroke
...d75, whose stroke occurred six months to six years previously and have a fixedfunctional motor deficit that has been stable for at least two months. The initial patient, Alma Cerasini, is a 62-year-old former healthcareworker who suffered a major stroke last fall, resulting in paralysis of herright arm ...Drug Prevents Hearing Loss Caused By Brain Tumor Therapy
...nly 3.7decibels. The Portland researchers previously had paved the way for brain tumortreatment with ca...pointed out. Therelated drug carboplatin, however, previously had caused only modesthearing loss when used to treat patients with cancers in other parts ofthe bod...... the Committee on Safety of Medicines. Severe and previously unknown adverse drug reactions to new products are more likely to be reported to the Committee. The authors believe that under-reporting and this bias in reporting needs to be addressed and that doctors should report all adverse reactions, however m...