Tag: "previously" at medical news

Weekly Taxol (paclitaxel) plus Paraplatin (carboplatin) is safe and effective in patients with advanced lung cancer

...e study presented today enrolled 214 patients with previously untreated advanced and metastatic NSCLC to determine which of three weekly regimens of induction TAXOL plus Paraplatin was the most safe and effective. On the other two arms of the trial, patients received four cycles of both TAXOL (100 mg/m2) and P...

Interferon Alfa 2b extends overall survival and relapse-free survival in patients with high-risk melanoma, reports University of Pittsburgh-led U.S. I

...el vaccine that also targets a form of T cell that previously has not been capable of being stimulated by vaccines, the helper CD4 T cell. According to Dr. Kirkwood, as the preliminary results of each of these approaches shows promise, they will be factored into the interferon approach that now has become the f...

'Unheralded safety net' providing state health practitioners for under-served areas

...he better known federal programs," he said. "These previously unheralded state programs, almost invisible nationally, are now a major portion of the U.S. health-care safety net and should be monitored, coordinated and evaluated. State programs no longer should be omitted from listings of safety net initiatives ...

New research shows major sleep disturbances overlooked in management of patients with Parkinson's disease

...y to achieve optimal improvement in akinesia which previously has been difficult to assess accurately". Additional studies presented confirm efficacy of cabergoline Additional research presented at the meeting supports the use of cabergoline in the management of PD patients. Presenting the findings, Dr H...

Doctors use novel methods to more effectively treat lung cancer

...ry tumors move when patients breathe, doctors have previously had to treat a wider area to hit this moving target in order to ensure that the lung tumors receive the ideal dose of radiation, increasing the side effects of treatment. However, physicians at Memorial Sloan-Kettering have discovered a way to immobi...

Irradiation, refrigeration can add to beneficial effects of wine grapes

...m damage, Tomas-Barberan said. The same effect has previously been found in apples, cherries and corn. Irradiation has no known side effects, he added. Elevated levels of resveratrol in red wine are generated during the fermentation process, so the additional benefits of irradiation are less significant for gra...

Genetics likely to be a major factor in osteoarthritis of the hip

...ows that the risk to siblings is even greater than previously thought, at around three to eightfold the rate of prevalence in unrelated people....

AstraZeneca reaffirms belief in CHARM study

...roup of patients with congestive heart failure not previously studied i.e. with preserved left ventricular systolic function (LVEF > 40%). Another arm specifically includes patients with impaired left ventricular function who are intolerant of ACE inhibitors. This allows a comparison of Atacand (candesa...

Researchers identify new genetic risk factor for HIV infection

...own to affect how one responds to HIV, such as the previously discovered CCR5(32 alteration, which prevents the T-cell receptors that HIV uses from being made in the first place. This change makes one extremely resistant to the disease. But Dr. Murphy cautions that people should not think themselves immune. ...

Study finds serious bone loss in 90 percent of women with anorexia

...cation in most women with anorexia, but it was not previously known whether that bone loss resulted primarily from the estrogen deficiency or from overall malnutrition. The study enrolled 130 women in their mid-20s with anorexia nervosa, most of whom did not have normal menstrual periods. Some participants had...

Researchers image language recovery after stroke

... and his colleagues at the School of Medicine have previously found that this region is very active in healthy volunteers during slightly challenging language tasks. For example, participants were asked to form a word that starts with "cou". When they think of a response, such as "cousin", this frontal area of ...

Early treatment of blinding eye disease in infants can prevent severe vision loss

...vision loss from ROP, ophthalmologists were forced previously to defer treatment until it was clearly indicated. Unfortunately, as it turns out, delaying therapy can leave infants who might benefit more from early treatment with poor visual outcomes. The Early Treatment for Retinopathy of Prematurity (ETROP)...

Gene mutations found that lead to prostate cancer in mice new mouse model developed to study the disease

...f prostate cancer in humans. MSKCC researchers had previously found that loss of the p27 protein in men led to a higher rate of recurrence for prostate cancer and a poorer long-term survival. The new finding may allow doctors to eventually refine their diagnosis and treatment of tumor types in men. However, f...

New procedure makes kidney transplant an option for thousands on waiting list

...e transplants possible for thousands of people who previously were unlikely to have a successful transplant. The advancement, called positive crossmatch transplants, greatly reduces the chance of organ rejection in patients with elevated antibody levels. Previously, these elevated antibody levels made tissue re...

Researchers at Cedars-sinai find four more genes that may play a role in the development of malignant brain tumors

..., it looks malignant, said Dr. Ljubimova. This had previously been theorized but gene array technology allowed us to discover that fact. According to Dr. Ljubimova (pronounced Lou-bee-mo-va), as new genes are discovered they contribute to a profile that can be used to monitor tumors, plan appropriate treatment,...

Researchers build on discovery of potent potential antibiotic

...higan College of Pharmacy researchers have found a previously unknown family of metal-requiring enzymes in bacte...University School of Medicine, Woodard's group had previously determined the crystal structure of the enzyme in the bacterium E. coli. However, it was impossible...

Bad habits, non-cholesterol risk factors in youth linked to fatty plaques

...s risk of heart attack to one-fifth of what it was previously and possibly even more," McGill adds. He notes that the percentage of smokers was "very high" among the study subjects 44 percent compared to 25 percent to 30 percent for the same age group in the general population. "We believe this hig...

UCSF researchers move in on role of brain's naturally occurring marijuana

...e pre-synaptic cells was CB1. Other scientists had previously determined that this receptor for marijuana existed, though it had not been clear where or how it acted in the brain. Still others had determined the existence of two naturally occurring cannabinoids, though, again, their location and role in the bra...

Duke chemists synthesize fungus compound that could lead to oral diabetes drugs

...ed. "And one area that combinatorial chemistry has previously not really made any inroads into is naturally occurring compounds." Combinatorial chemistry seeks to efficiently synthesize and identify chemicals with desired traits by mixing and matching large "libraries" of different molecular building blocks...

Highest known catalytic rate for superoxide dismutation achieved

...f the companys synthetic manganese-based compounds previously shown to exert protective anti-inflammatory effects in animal models. The compounds, part of a family being developed by Metaphore, mimic the action of the bodys prime free radical fighting natural enzyme, superoxide dismutase (SOD). The original ...

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