Researchers close in on breast cancer vaccine
...protein that the immune system may recognize). The primed T-cells then would proliferate and attack when they met with mammaglobin-A antigens. "Mammaglobin-A is involved in breast development and secreted in breast milk," Mohanakumar says. "So we had to prove first that we could elicit an immune response to...Studies underscore genetic involvement in nicotine addiction & aggressive hostility
...'s neural receptors were exquisitely sensitive and primed to over-react, in part by producing extra cortisol. Tying together the three findings, Hennig concludes that, "We found that gene polymorphisms contribute to the variance that can be found in neuro-endocrine challenge tests and personality question...HIV vaccine trial breaks ground for future research
...vior may have been exposed frequently to HIV and a primed immune response, probably cellular or humoral, could have worked with the vaccine and caused a greater ability to resist the virus. For the non-white group, the authors suggest that biological differences in immune response or genetic markers of resi...Gene vaccine protects mice against development of Her2/neu breast cancer
...s - and which creates a long-lasting immune memory primed to attack breast cancer cells that are studded with HER2/neu proteins, he says. In the experiments, three groups of seven mice were treated with three injections of a vaccine. The "control" arm received a VRP vaccine that contained an influenza prote...First US SARS vaccine trial opens at NIH
...ctual SARS virus, his or her immune system will be primed to neutralize it. "It is truly remarkable that less than two years ago we were facing an unknown global health threat, and now we are testing a promising vaccine that may help us to counter that threat should it re-emerge," Dr. Fauci said. After SARS...Multi-center study finds therapy boosts kidney transplants in 'highly sensitized' patients
...une system is then "sensitized" to those antigens primed with antibodies to attack, even if the antigens arrive in the form of a potentially life-saving donated organ. The degree of sensitization is measured in terms of "panel reactive antibody" or PRA levels. For a non-sensitized patient with end-stage re...Money issues leading cause of holiday stress for Americans
...ing care of yourself helps keep your mind and body primed to deal with stressful situations. ...Reconstituted blood is better for infants' heart surgery than fresh blood
...s while surgeons make repairs. The machine must be primed with donor blood because babies do not have enough of their own blood to supply both the machine and their tiny bodies. Blood priming of the cardiopulmonary bypass machine is not necessary for adults, whose blood volume is larger. Traditionally, s...ISSIR launches The Journal of Sexual Medicine with Blackwell
...xpert in the field, said "the (editorial) board is primed for the task of making this the major journal for the study of sexual medicine, representing basic science research and the clinical applications of evaluation and treatment of sexual health issues." Dr. Goldstein, his editorial team, and the entire...National survey finds U.S. public enthusiastic about cancer screening
...ultiple comorbidities [illnesses]." The public is primed to believe that there is value in having any test that is marketed as being able to find early cancer, suggest the authors. They conclude, "The challenge now is to balance messages and reduce the public's risk for overtesting and overtreatment." T...Binghamton University, RPI and Infotonics Center team up to form national packaging power
... unique packaging capabilities of the alliance are primed to provide the kind of breakthrough research needed by this rapidly emerging field. The Infotonics Technology Center Inc. is a not-for-profit corporation that operates New York State's Center of Excellence in Photonics and Microsystems. Infotonics is...Possible new cancer therapy shrinks tumors in melanoma patients, Science authors report
...patients 9 and 10, that subfamily turned out to be primed to attack a particular antigen called "MART-1." The antigen is involved in producing pigmentation, and is thus found in normal skin and iris cells, as well as in melanomas. Some of the patients who had positive responses to the therapy developed cer...U-M study finds new target in war against graft-versus-host disease
...row into an army of destructive effector cells all primed to attack and kill the host. Cytokines can travel through the bloodstream and, therefore, inflict their damage from a distance, Ferrara adds. So theres no need for direct contact between donor effector cells and host target cells, and antigen express...Substantial increase in death rate after bypass surgery for people with anaemia
...patients having had blood transfusions or the pump primed with blood preoperatively as a routine precaution. Jens Peder Bagger (one of the investigators) comments: Since correction of anaemia around the time of surgery did not improve survival rate, our findings suggest that patients who present with anaem...Researchers identify a key 'brake' of the immune response
...out rejection had T-suppressor cells that had been primed to suppress a response to foreign hearts. The findings of the study also have implications for type I diabetes and other autoimmune diseases, Dr. Suciu-Foca says. In autoimmune disease, the immune system attacks normal body tissue rather than being t...Failure at nonconscious goals explains negative 'mystery moods'
... Results showed that, for participants primed with an achievement goal, tho... But, for participants who were not primed to have an achievement goal, there were no mood differences between those who h...Essential 'Allergy Feedback Loop' Discovered By Hopkins
...ustmites and pollen. When bits of pollen bump into primed mast cells and basophils,the cells release histamine and other agents that cause irritating symptoms. Current over-the-counter remedies block symptoms while the underlyingIgE-driven allergic process continues unabated. But anti-IgE disrupts ...Baby Talk: Parents Do Make A Difference, By Promoting Childhood Chatter, From Birth To Age 3
...k at birth,Hirsh-Pasek points out. Yet, they're so primed to language, children in manyregions pick up two or three different languages with no difficulty. "That's the irony," Golinkoff says. "We don't trust them alone. They can't crossthe street. We don't let them have sharp objects. Little ones are helple...T-Cell Memory Finding May Provide Key To Cancer, AIDS Vaccines
...y. "The great thing was that the memory cells were primed and ready. They requiredno help from other cells -- no cytokines, no co-stimulation," saidAshton-Rickardt. "They remembered and went after their targets as soon as theywere exposed to them again. Although mice with normal immune systems take two orth...