12-year-old Oregon girl is first child to receive new bone growth material in her skull
...es in Emily's skull. BMP is asynthetically created product that initiates molecular and cellular activitythat causes the body to grow new bone-forming cells called osteoblasts. Theseosteoblasts then develop into healthy new bone structures. In October 1998 Emily had BMP applied to a gap in the right side of ...Drug companies responded poorly to requests for information from doctors in Pakistan
...dequate or appropriate responses then they request product information from drug companies, claim doctors from Pakistan in this week's BMJ. Assad Hafeez from Khan Research Laboratories Hospital in Islamabad and Zafar Mirza from The Network for Rational Use of Medication in Pakistan believe that the decision ...UNC-CH nutrition expert says nation should regulate some diet supplements
... Digitalis lanataafter an individual consuming the product suffered a complete heart block," hewrote. "The FDA proposed a regulation to limit the amount of ephedrine alkaloidsin dietary supplements (ephedra, Ma Huang) after serious side effects, includingdeath, were observed." Also recently, the agen...Researchers discover potential new approach to treating cystic fibrosis
...ects to conduct its clinical trials of a DHA-based product incollaboration with the foundation, which has est...is gene. Dr. Freedman expects to test theDHA-based product in patients with pancreatitis. Beth Israel Deaconess is a major teaching hospital for Harva...Baby walkers may impede child development
...rs as responsible for more injuries than any other product forchildren. A 1992 petition by the American Academy of Pediatrics and othergroups called for an outright ban on baby walkers, which have been associatedwith at least 11 deaths since 1984. "When the danger factor is considered in conjunction with th...Northwestern researchers present findings at Neuroscience Meeting
...he Clock gene, or one of the genes that itsprotein product interacts with, fails to function as well as it does in youth.This may help explain why the circadian rhythms of many species of animals,including humans, function differently or more irregularly in old age. Kolker and colleagues studied two differen...Researchers uncover gene related to acute leukemia
... and flips around--an inversion translocation. The product of the new gene created by inv(16) alters the activity of a proteincalled AML-1. AML-1 is a transcription factor--a protein that turns other geneson and off. It is what Hiebert calls a "master regulator" because it controlsmajor cellular pathways t...The American Association of Pharmaceutical Scientists releases latest findings at Annual Meeting
...ecific drug and 36% of the time they prescribe the product in question 77% of physicians linked patient requests to TV advertising, 51% to print Link Between Aspirin Use and Acid Reflux Disease -- Researchers have found that non-steroidal anti-inflammatory agents like aspirin and ibuprofen are strongly a...New sterol spread can reduce bad cholesterol
... you can get another five percent reduction with a product like this, you're talking about a 10 to 15 percent reduction in LDL cholesterol, which over time may reduce the risk of heart disease by 15 to 30 percent or more," says Maki. "Compared to the 20 percent reductions associated with some drug therapies ...Novel neurotransmitter overturns laws of biology, offers potential for stroke treatment
... The enzyme, serine racemase, is as unusual as its product in that it forms D-serine from L forms already in cells. "No other mammalian enzyme behaves like it," Snyder says. The oddity of having an enzyme that converts amino acids from a left to a right-handed form makes it an ideal drug target, he adds. I...American Association of Pharmaceutical Scientists tapped to manage PQRI
...g policy, whilestill ensuring the highest level of product quality. The technical committee then reviews the...be included in a regulatory submission to document product quality attributes," said Roger Williams, Deputy Director of the Center for Drug Evaluation and Rese...... Zealand, MEDIHONEY® is thefirst topical honey product in the world to achieve Therapeutic Goods Administ... assurance of TGA listing, a limited amount of the product is being released for public use,"he said. "We want members of the public who try it to tell us how ......industry estimates show that a delay in bringing a product to market results in the loss of more than $1 million in revenues each day. The new "clicks and mortar" organization also represents an early entry into the next generation of Internet healthcare companies, whose business strategy from inception i...AAPS announces AAPS PharmSciTech, the association's second online journal
...inate scientific and technical information on drug product design, development, evaluation and processing wor...invites manuscripts in all areas of pharmaceutical product development and manufacture, including pharmaceutical excipient evaluation, with a focus on practica...Duke geneticists unraveling the tangled web of autism
... that their withdrawn, silent, autistic child is a product of their own poor parenting. But the Duke researchers are now demonstrating that autism is a complex genetic syndrome that may actually turn out to be several related disorders, each with its own individual treatment. "One of the biggest difficulti...AAPS Workshop to Examine Chemistry and Manufacturing Controls Trials, Emerging Products
...cuss factors that have resulted in successful drug product registrations from the perspective of Chemistry an..." Topics of focus include drug substances and drug product specifications, test methods and validation, and stability data. Although there will be formal prese......r, he says, but is loosely coupled. This work is a product of Sandia's Laboratory Directed Research and Development program as a dual-use application of radar technology and conformal antennas. It is related to the lab's projects in applied electromagnetics that affect diverse technologies, including communi...AAPS workshop to examine changes in analytical methods and packaging
...mpact of these changes on drug substances and drug product quality; andTo generate a summary report that can be utilized by the FDA in the development of guidances on post approval changes in these areas. Speakers at the meeting include: Vinod P. Shah, Ph.D., FDA; Dhiren N. Shah, Ph.D., Aventis Pharmaceutica...... in February 1999. The efficacy and safety of the product was demonstrated in 429 adult overactive bladder patients with incontinence episodes in three controlled studies and one open-label study. In the placebo-controlled study, Ditropan XL demonstrated efficacy superior to placebo in the reduction of ...