Experimental drug reverses effects of Fabry disease in mice
...ease is caused by a genetic mutation that prevents production of an enzyme called alpha-galactosidase A, which c...gans in the body. Since the U-M compound inhibits production of these glycolipids, Shayman plans to test its effectiveness in these related disorders, which incl...Scientists meet in Connecticut to discuss research findings
...rtment, will demonstrate the chemistry behind wine production and its challenges in the Connecticut area. A tasting follows the presentation. Tuesday, June 20, 4:30 - 6:00 p.m., South Campus Dormitories. WHO: Sponsored by the Connecticut Valley Section of the American Chemical Society WHAT: Northeast Regional m...Study finds marijuana ingredient promotes tumor growth, impairs anti-tumor defenses
...r growth is prompted by THC's ability to stimulate production of IL-10 and TGF-beta, which inhibits anti-tumor immune response....War on bacteria could leave drug-resistant strains unchecked
...life. If the baby's environment is too clean, the production of T-helper 1 cells is not adequately stimulated and the immune system overproduces T-helper 2 cells, which in turn make antibodies to fight allergens. That imbalance of T-helper cells could result in lifelong allergies or asthma. "Just as a child ...Product design and drug development breakthroughs help the environment
...ul chemical reactions associated with the original production process, while increasing the product yield by more than 25 percent. U Using water, not hazardous solvents to spray on plastic coating (Pittsburgh, Pa.) - Scientists with Bayer Corporation, in Pittsburgh, Pa., devised polyurethane coatings that can b...Pacific Northwest National Laboratory wins three R&D 100 awards
...Resulting technologies are reducing losses on food production lines, helping to ensure the safety of food and may replace glass with engineered plastics in electronic display panels. Each year R&D conducts the R&D 100 Award competition to honor the most promising new products, processes, materials or softw...UI-led study shows experimental anti-cancer drug also has anti-HIV properties
...ription, a multi-step process which results in the production of ribonucleic acid (RNA). Cells use the genetic information encoded by these long RNA molecules to make proteins. Flavopiridol effectively blocks the action of an enzyme called P-TEFb, which controls one of the steps in the transcription process. In...American award recognizes Swiss researchers
...uppressed the release of growth hormone. Excessive production of growth hormone -- a condition called acromegaly -- can cause gigantism and shorten life span. But native somatostatin survives only a short time in living tissue. "That made it very hard to characterize," explained Bauer, a chemist with Novartis P...Scientists develop polymers with nitric-oxide releasing particles
...al is to reproduce the body's natural nitric oxide production system, which prevents clots from forming inside blood vessels," said Mark E. Meyerhoff, U-M professor of chemistry. At the American Chemical Society meeting held here this week, Huiping Zhang, U-M graduate student, presented results of recent stud...Vitamin D shows promise as cancer prevention drug
...his country, behind heart disease. Development and production of any drug that is scientifically proven to prevent cancer in humans would be a historical milestone, says Posner....Drug therapy significantly extends lifespan of worms
...ochondrial defect causing increased oxygen radical production and rapid aging. The findings were reported in the September 1, 2000 issue of Science. The collaborative research was conducted by Simon Melov, Ph.D., of the Buck Center for Research in Aging and formerly of the Center for Molecular Medicine at Em...... phases of prostate cancer treatment to help block production or action of the male hormones that have been shown to fuel prostate cancer. ...... high risk for depression showed similar decreased production of growth hormone when given GHRH as currently or recently depressed children. The never-depressed children at high risk to develop depression and the children who were already depressed both secreted significantly less growth hormone than the norma...NIAID awards major malaria vaccine research contract
...rporation (SAIC), McLean, Va., for malaria vaccine production and support services. The contract will support t...o clinical research on malaria vaccines, including production of pilot lots of clinical quality vaccines, has been a particular bottleneck for the field of malari...More protests against abortion pill
...ters fear theirs may be a pyrrhic victory, because production of a second pill that has to be taken with RU486 is now under threat. RU486 (mifepristone) was approved in Britain nine years ago as an alternative to surgical abortions in the first two months of pregnancy. But American anti-abortion campaigne......urrently available will enhance the value of their production systems," he says....VA trial to weigh aspirin against other anti-clotting drugs in heart disease patients
...emicals called prostaglandins. Aspirin reduces the production of prostaglandins and therefore may interfere with part of the benefit of ACE inhibitors. This vitally important issue can only be addressed in a large controlled study such as WATCH (Warfarin and Antiplatelet Therapy in Chronic Heart failure), wher...FDA, drug industry and scholars find success in effort to tackle regulatory issues
... Current regulations advocate the testing of each production batch of a powder-blend drug. However, industry experience suggests that testing every batch is not necessary or meaningful because the current blend sampling technology is flawed and doesnt necessarily provide representative results. The FDA has a...Sustained use of anti-depressants increases cell growth and protects cells in the brain
...It is one of only a few regions of the brain where production of neurons occurs in the adult brain of animals, including humans. Several studies have demonstrated that stressful experiences, both physical and psychological, lead to neuronal loss or atrophy in the hippocampus. Other studies show that anti-depres...