Major advance in chemotherapy in breast cancer
...en tested in the BCIRG 001 trial, to significantly prolong disease-free survival and survival," said Miguel Martin M.D. from the Medical Oncology Department, Hospital Universitario San Carlos, Madrid, Spain, chairman of GEICAM. Study Design The BCIRG 001 study was designed to determine if Taxotere, one of ......epress the recipient anti-alloantigen response and prolong graft survival following transplantation. Furthermore, the authors determine that this phenomenon is dependent on the presence of CD8+ cells at the time of antigen challenge. The data implicate Notch signaling in the regulation of peripheral immunity...PRAECIS PHARMACEUTICALS INC receives FDA approval for Plenaxis
..., or to other variables. Because Plenaxis TM may prolong the QT interval, physicians should carefully consider whether the risks of Plenaxis TM outweigh the benefits in patients with baseline QTc values greater than 450 msec (e.g. congenital QT prolongation) and in patients taking Class IA (e.g. quinidine...Experimental drugs show promise in halting brain tumors
...t cause cells to rapidly reproduce, to unnaturally prolong their lives, to grow blood vessels to support their growth, and to invade surrounding tissue -- all of which are hallmarks of cancer, said Rich. The new drugs work by plugging up small "pockets" inside the cells where a molecule called ATP would norm...UCLA researchers to test experimental pill
...atments we have now for advanced colorectal cancer prolong life, but unfortunately, they are not a cure," Hecht said. "We need to look for improved methods of treatment, and angiogenesis inhibitors have been promising." The two studies are being conducted at multiple sites across the country, Hecht said. Res...In lab studies, blocking expression of gene reduces invasion of deadly brain tumor cells
...ional therapies or with other genetic targeting to prolong disease-free periods and increase survival." The study was supported by a grant from the Maxine Dunitz Neurosurgical Institute. It was conducted by scientists from the Institute, the Ophthalmology Research Laboratories at Cedars-Sinai, Osaka (Japan) ......andard of care in these patients, to see if we can prolong the response to hormone therapy and reduce the duration of individual courses of hormonal therapy," says Tannir. "Prostate cancer does express EGF receptors in late stages and androgen independent cancers have high expression." Tannir, as well as o...Molecule expressed early in pregnancy may help patients tolerate transplants
...recipients from immunosuppression to see if we can prolong graft survival," Dr. Grandas said. The ability to identify the best matches for patients has improved and the drugs patients take to avoid rejection have as well, Dr. Grandas said of the last 20 years in the transplant field. Ironically the net effe...Darifenacin increases 'warning time' for OAB sufferers
...for overactive bladder (OAB), has the potential to prolong "warning time" the period between the first sensation of urgency and micturition in patients experiencing OAB syndrome. This is according to data presented at the International Continence Society's 33rd Annual Congress in Florence, Italy1. Darifen...UB begins groundbreaking study on 'net effect' on patients of HIV treatments, other drugs
...re treating people with one basic goal in mind: to prolong their lives," said Gene Morse, Pharm.D., principal investigator, professor and chair of the UB Department of Pharmacy Practice and associate dean of the School of Pharmacy and Pharmaceutical Sciences. "Now we have the drugs to suppress viral replicat...1st successful national CQI intervention in medicine reported
...as chosen because its use has been demonstrated to prolong survival in younger patients, but at the start of the study, its use in elderly patients was considered controversial. The trial tested whether a medical specialty society could leverage physician motivation nationally in a call to action at the lo...Study: old age wont boost health-care costs as much as some have predicted
..."heroic," and hence expensive, efforts are made to prolong their lives. Once members of that generation survive into their mid-80s or so and beyond, many medical procedures will become too risky for their older bodies and will be avoided in many cases, the UNC School of Public Health researchers say. The re...Thanksgiving menu stuffed with healthy choices
...lp protect against heart disease. Honey also helps prolong the freshness of meat, protects against off flavors, and guards against harmful byproducts of meat oxidation that may increase the risk of heart disease, the researcher says. The range of antioxidants in honey is comparable to that in apples, bananas...Doppler-guided fluid administration during surgery improves outcome
...ditional problems, including sepsis, which tend to prolong hospital stays and can cause death," Gan said. According to Gan, EDM technology is easy to use, and actually takes less time and discomfort to insert than traditional methods, which includes inserting a catheter into the aorta or pulmonary artery to ...New protease inhibitor held HIV at undetectable levels for four years
...tions for initial therapy. Viral suppression helps prolong the time to development of resistance, which is an important cause of treatment failure," Murphy said. In this ongoing phase II study, 100 patients who had not previously received antiretroviral therapy were given one of three doses of Kaletra in ad...Marijuana-derived compound targets pain, inflammation
...compound could slow the spread of cancer cells and prolong survival in mice with brain tumors. The U.S. Army is evaluating it as a topical drug to relieve the blistering effects of sulfur mustard gas. How it works is still under investigation. The compound appears to suppress chemical mediators, such as pros...Newer lung cancer treatments extend survival longer than traditional regimens
...hat paclitaxel- and carboplatin-based regimens can prolong survival of patients with this disease," said John Hainsworth, MD, lead study author and Director of Clinical Research at the Sarah Cannon Cancer Center. "Survival beyond two years has been uncommon with previous treatments for advanced non-small ce...High cholesterol and calcification are to blame for aortic valve disease
...tic valve disease process. Earlier statin use may prolong the time to severe disease and the need for surgical valve replacement. Statins are drugs that block the formation of cholesterol in the liver and increase the production of the receptors on liver cells that clean the bad cholesterol from the blood....Molecularly targeted drug slows tumor growth in patients
... to build on this finding in order to meaningfully prolong the lives of patients with advanced cancer." More than 20 additional clinical trials are currently underway to evaluate bevacizumab as a treatment for various types of cancer. The drug is being tested in phase III trials for breast and colorectal ca......not be the mere extension of life. It should be to prolong the duration of healthy life." Olshansky and Carnes are authors of "The Quest for Immortality: Science at the Frontiers of Aging (Norton, 2001). Hayflick is author of "How and Why We Age" (Ballantine, 1996)....