Starzl Institute researchers to develop cell-based strategy for tranplant tolerance
... derive from lymphoid tissue or blood, allowed for prolonged survival in a mouse heart transplant model, even without the use of drugs to control rejection. In contrast, the better-known myeloid dendritic cells accelerated the rejection response. According to the researchers, transplant patients who are off i...New treatment strategies offer hope to women with breast cancer
...py, however, produces severe side-effects, such as prolonged suppression of blood cells, infection and bleeding. Researchers have focused their studies on high-dose chemotherapy both in patients whose cancer has spread to other organs, as well as high-risk patients at an early stage of the disease. "There we...Pituitary tumor cells in Cushings syndrome found to express large amounts of protein receptor
...ost common type of Cushing's syndrome is caused by prolonged high-level exposure of a hormone called ACTH (adrenocorticotropin), which is secreted in excess by tumors of the pituitary gland, situated at the base of the brain and, which controls growth, metabolism and reproduction. Although the disorder is rare......shown it to be a potent stimulant. How it produces prolonged alertness is not well understood, but it is thought to act specifically in the brain's pre-frontal cortex. This is one of the most active areas of the brain in people who are awake, governing planning, memory and what we pay attention to. The drug's ...Exploring the relationship between alcoholism and serotonin one step at a time
...use and dependence versus changes that result from prolonged toxic exposure of the brain to alcohol."...Meeting emotional needs of family makes a difference in the ICU
... most believed that the patient's life was neither prolonged nor shortened unnecessarily. "Although some of the study findings are limited to Canadian ICUs, the importance of adequate communication, good decision-making, and respect and compassion in quality critical care crosses many settings, borders, and c...Symptoms of depression signal shorter lives for people with cancer
...er carries such emotional upheaval that a person's prolonged feelings of depression can eat away at the possibility for long-term survival. In a new study of cancer patients published in the current issue of Psychosomatic Medicine, researchers have found that people's lives were more likely to be cut short whe...FDA approves Baxters ADVATE for the treatment of hemophilia A
... nausea, pain in the upper abdomen or lower chest, prolonged bleeding after post-operative drain removal, decreased red blood cell count, joint swelling and shortness of breath. Non-serious, but severe related adverse events include: fever, headache and decreased coagulation factor VIII levels. ABOUT ADVATE...Other highlights in the August 6 issue of JNCI
...he development of endometrial cancer is related to prolonged exposure to estrogens without cyclic exposure to progesterone. Phytoestrogens may have antiestrogenic effects. Phytoestrogens are found in soy-based foods, and many foods contain added soy (such as white bread) or have low to moderate amounts of phyt...UCI researchers identify link between infant seizures
...dicine study has identified why infants who suffer prolonged fever-induced seizures are more susceptible to fur...s and epilepsy as adults. According to the study, prolonged fever-induced seizures increase the brain's production of endocannabinoids, a natural marijuana-rela...Yale expert warns children may lead shorter lives than their parents because of obesity
...and other venues; sedentary behavior stemming from prolonged use of computers, video games and television; communities designed to make it difficult to bike or walk to schools and work; product placement of foods in television and movies; partnering of children's media giants with the food industry; schools "a...Existing anti-inflammatory drug could help children suffering from an inherited bone disease
...s conventional approach is far from perfect, since prolonged treatment can damage kidneys, Dr. Quigley said. "We are hoping that this very simple treatment with Indomethacin can either do away with that treatment or at least make it so physicians don't have to use such high dosages and won't damage kidneys," h...Long-term outcome of epilepsy surgery is favorable for many
...cting seizure freedom, although all patients had a prolonged duration of epilepsy prior to surgery. The group who remained seizure-free had epilepsy for an average of almost 16 years prior to surgery. The group who relapsed had epilepsy for an average of more than 20 years prior to surgery. In an editorial pub...St. Jude identifies ways to improve treatment of childhood leukemia in Honduras
...that families abandon children's treatment was the prolonged travel times faced by families in distant parts of Honduras. These families sometimes must travel more than five hours for weekly chemotherapy treatment in the capital city, Tegucigalpa. "Families face not only the costs of the bus ticket, but also t...Manganese in intravenous nutrition a problem for patients needing intestine transplants
...ith liver failure as have been seen in miners with prolonged exposure to ore, in whom manganese poisoning was first described. Removing manganese from TPN formulas can reverse these neurological deficits,Karen Laughlin, PharmD, of the University of Pittsburgh Medical Center's Thomas E. Starzl transplantation ...Study suggests life insurance should cover people treated for HIV
... introduction of HAART over the past few years has prolonged the lives of many people with HIV-1 infection. Bernard Hirschel from Geneva University Hospital, Switzerland, and colleagues measured mortality rates in around 4000 people enrolled in the Swiss HIV Cohort Study (SHCS) (an ongoing study of HIV-positiv...First-line use of voriconazole yields better outcomes for life-threatening fungal infection
...s the treatment of invasive aspergillosis requires prolonged therapy and can be expensive, Dr. Lewis and other investigators analyzed data from the Herbrecht trial to evaluate "real-life" antifungal costs for aspergillosis therapy. The study (Poster A-1359) accounted for current drug acquisition costs of prim...Results from first clinical trial using GVG to treat addiction
...tional addiction treatment center in Mexico report prolonged abstinence and the elimination of drug craving in ...tal cocaine addiction treatment protocols. But the prolonged duration of abstinence far exceeds what other pharmacological treatments have achieved," said Frank ...Duke to lead first comparative trial of hepatitis C therapies
...ent health and quality of life and translates into prolonged survival, a lower incidence of liver cancer and may prevent the need for liver transplantation," McHutchison said. McHutchison has served as a paid consultant to Schering and has received research support and lectured on behalf of both Schering-Ploug...Sudden cardiac death: New risk factor first identified in Illinois family by SLU cardiologist
...ECG). "It's been well-known for many years that a prolonged QT interval can lead to sudden cardiac death," says cardiologist Preben Bjerregaard, MD, professor of internal medicine at Saint Louis University School of Medicine and Director of the Electrophysiology and Pacemaker Service at Saint Louis University...