Latest cancer research features small molecule therapy, and the preventative benefits of sunshine
...We have identified a small molecule with drug-like properties that is a candidate for further preclinical development," Rice said. CX-3543 selectively suppresses cMyc activity by specifically binding to the cMyc quadruplex, he said. G-quadruplex structures are four stranded DNA secondary structures. Cer...Researchers testing compounds that may stop replication of T-cell leukemia virus
... just 45 minutes. This method measures the optical properties of the compounds and performs analysis without separating the chemical products in each compound. Despite what can be tedious work, the researchers express excitement about their studies."It's the unknown," Dennison said. "There's no rule book that c...Increasing the body's good cholesterol may be a pill away
...sterol). And, although the drug's CETP-inhibitor properties proved effective when administered by itself, its effectiveness was maintained when given in combination with a statin -- which is the most common class of drugs used to lower LDL cholesterol levels. The implications of this study which took pla...Statins and aspirin may protect against severe vision loss in elderly
...proven, explanation involves the anti-inflammatory properties of both statins and aspirin, Duncan said. Tissue studies of patients with CNV reveal chronic inflammatory cells and other evidence of inflammation. Statins inhibit production of proteins involved in inflammation and reduce the role of immune cells in...When 'switched on' muscle stem cells morph to resemble nerve cells
...at show biochemical, physiological, and structural properties of neurons. The researchers say the advance, publi...cle progenitor cells to become cells that have the properties of neurons, it may be possible to use the same kind of technique to potentially change the fate of o...How cancer neutralizes T cell attack
...are healthy, they proliferate, and their cytotoxic properties are restored." The team is already conducting early-phase clinical trials of cancer vaccines based on the Melan-A/MART-1 antigen, through its participation in the Cancer Vaccine Collaborative, a partnership between LICR and the Cancer Research Insti...Adding menthol to topical creams for osteoarthritis provides significant pain relief
...ream. Menthol has been shown to possess analgesic properties thereby reducing the sensation of pain. A new study extends previous research and examines the effects of a topical cream consisting of cetylated fatty acids, along with the addition of menthol, on pain and functional performance in patients with kne...Study finds certain compounds in beer, wine effective in slowing breast cancer cell growth
... could be partially related to the pharmacological properties of polyphenolic compounds present in red wine. A ...t to examine whether phenolic compounds could have properties that would be effective in fighting breast cancer, the most commonly diagnosed nondermatologic cance......esearch on the production, perception and physical properties of speech sounds. Up to now, MRI primarily has recorded still images of the dynamic vocal tract, data that have been useful but limited in telling researchers about the timing of speech. But, as anyone who has ever tried a tongue-twisting phrase lik...Mycophenolate mofetil superior to azathioprine: Slows vascular disease progression after transplant
... The antiproliferative and immunosuppressive properties of CellCept appear to slow progression of hyperplasia and reduce damaging immune reactions in the intimal cells. "IVUS makes it possible to do site-to-site assessment of maximal intimal thickening in the same location in the artery at baseline a...Combination therapy w/ ACTOS (pioglitazone HCI) shown to improve components of diabetic dyslipidemia
...esting that medications like ACTOS have additional properties that address the lipid abnormalities associated with the disease, such as dyslipidemia common in patients with type 2 diabetes," noted Dr. Khan. ACTOS is known as an insulin sensitizer because it directly targets insulin resistance, a condition in w...Alternative/supplemental breast imaging methods tested
...y all provide detailed information about different properties of breast tissue. * EIS: This painless test uses a very low voltage electrode system to examine how the breast tissue conducts and stores electricity. Living cell membranes carry an electric potential that affect the way a current flows, and differe...Electromagnetic breast imaging tested as alternative to mammography
...nd stores and conducts an electrical charge. These properties help researchers estimate specific breast characte...gain a better understanding of the electromagnetic properties of breast tissue," said Steven Poplack, M.D., professor of radiology at Dartmouth Medical School and...Cord blood stem cells save children with Hurler's syndrome
...'re able avoid radiation in large part because the properties of cord blood enable us to achieve engraftment more readily and with less manipulation of cells than is possible with adult bone marrow." The findings are yet another example of the promising capabilities of stem cells derived from umbilical cord blo...$5 million NIH contract to fund development of pediatric heart assist device
...Penn State, who will be responsible for mechanical properties testing of the blood sac polymers as well as providing general expertise in polymer chemistry, bulk properties and surface properties; and Keefe Manning, Ph.D., post-doctoral research fellow in the Department of...NIH launches study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus
...ystem after therapy. They will be looking for cell properties that may contribute to the faulty immune response found in lupus. B cell studies will be conducted by scientists at NIAMS, while T cell studies will be conducted by scientists at NCI. Researchers at the National Institute of Neurological Disorders an...Yerkes researchers discover combination of drug therapies reduces cocaine use in primates
... addiction studies because they elicit reinforcing properties in the brain similar to those experienced as a result of taking cocaine. The research team then substituted the DAT inhibitors for cocaine in order to determine their effectiveness in maintaining the use of the medications. Finally, Howell and the te...Antioxidant component of green tea blocks new but not established arterial plaque in mice
...ents of green tea leaves are known to have natural properties that counteract the harmful effects of oxidation i...t support tumor growth. Because of the antioxidant properties of the catechins in its leaves, tea also has been seen as a potential dietary intervention for cardi...Tufts professor launches program to mentor deaf students in state-of-the-art physics research
...tion of X-rays and light with polymers, mechanical properties of polymers, and the effects of thermal processing on the structure and ultimate properties of the polymers. An interdisciplinary team of professors and graduate students from Tufts is invol...Wartime spitfire strain test monitors stress on key heart artery - aortic aneurysm
...uld provide an even closer mimic of the mechanical properties of the original aortic aneurysm. He is also lookin...s equipment to draw on the more limited reflective properties of the original aortic aneurysm which would provide surgeons with a real time monitor of the stress ...