Chemist Turns To Self-Assembly To Create New Drugs
..." which of the resulting compounds bestmatches the prospective drug's DNA, RNA, or protein targets,which cause disease. The very best match elbows out all theothers to latch onto the target molecule. "With our technique, we try to find molecules to bindreceptors in much the same way nature has for millions ...National Health Study Launched On The Internet
...cted the National Runners' HealthStudy, a national prospective epidemiological study of 56,000 runners. Thesurvey has played a prominent role in the ongoing national debate overrecommendations on the desirable levels of physical activity. Williams alsolaunched a companion study, the National Walkers' Health St......on in urban and rural areas in northeast Scotland: prospective observational study) Acute myocardial infarction (death of part of the heart muscle) is most often due to coronary thrombosis (a blood clot). Thrombolytic treatment to try to dissolve the clot is a matter of urgency and, according to the British H...Tobacco Will Kill One Third Of Chinese Men
...azards in China: 2. Early mortality results from a prospective study) Click below to download PDF document You will require Acrobat Reader to view file. Click here for PDF document China now consumes one third of the world's cigarettes. In this week's BMJ researchers report on the largest-ever investigation...Heart Valve Abnormalities Examined In Relation To Duration Of Diet Drug Use
...ely collected information, it was not arandomized, prospective clinical trial, and that there were gender and racialdifferences between the group that used drugs and the group that didn't. Forexample, there were more white women in the treated group compared to thecontrol group. "It's the best study that can be...Stent Procedures May Be Unnecessary In Some Heart Cases
...ysis, thenext step is to validate the results in a prospective trial. The researchers analyzed data from 5,143 patients who received balloonangioplasty and looked at what happened six months later. Of those patients, 18percent achieved a stent-like result. Of all the factors that led to stent-like results that ...Heart Drug Finds New Use In Patients With Wolff-Parkinson-White Syndrome
...sion in 13 of the 14 patients. In a second ongoing prospective study, the researchers are examining themechanisms of how Ibutilide works. To date, eighteen WPW patients ranging inage from 4 to 75 years old have been given Ibutilide during EP study. Theresearchers have identified Ibutilide's effects on conducti...Second Annual AIDS Vaccine Day Honors Volunteers Nationwide
...ing scientists to betterunderstand the concerns of prospective HIV vaccine trial volunteers. One Phase III study that is testing AIDSVAX, a bivalent gp120 vaccine developedby VAXGEN, opened in the summer of 1998 and is expected to be completed in 2001. For information about events in specific areas, contact: ...Margin Width The Key To Control Of Ductal Carcinoma In Situ Of The Breast
... for DCIS stems from the fact that to dateonly one prospective randomized study has been published. This is protocol B-17,conducted by the National Surgical Adjuvant Breast & Bowel Project (NSABP),which strongly advocates excision plus radiation therapy for all patients withDCIS who elect to preserve their breas...Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...e markers weresignificantly related to survival. A prospective study in lung cancer is underway to verify those results. The researchers also plan to study the important esophageal cancer markers=effects prospectively -- to see if predictions based upon their new modelscorrespond with reality. This national eso...Study finds predictors for youth violence and drugs
...ngsagainst school records of actual events. "While prospective studies such as the present one are sorely needed," theauthors say, "theoretically rich studies are imperative to better understand theroots of adolescent violence." Working with Sussman on this study were Dent; IPR research associate professorAlan W...No health protection from alcohol -- but heavy drinkers face risk of stroke
...coronary heart disease, and stroke: results from a prospective cohort study of Scottish men with 21 years of follow up A large-scale long-term study of working men in Scotland, reported in this week's BMJ, found no support for the theory that drinking moderate amounts of alcohol has any protective effect on ......tal during amedical crisis. Dr. Shah says he hopes prospective studies will be conducted to test thehypothesis that treatment at large-volume hospitals does make a significantdifference in outcomes. The recently published study was retrospective --analyzing the results of previous outcomes. "In that sense, it re...Better psychiatric support needed for children who lose a parent
...service provision in parentally bereaved children: prospective case-control study) Children who have lost a parent are not all receiving the support services that they need, report a team of researchers from south east England in this week's BMJ. Service provision seems to be based on the age of the child an...Medicine, international law and weapons
...s on civilian injuries: retrospective analysis of prospective data from Red Cross hospitals) BMJ Volume 319 14 A...Cambodia after departure of a peacekeeping force: prospective cohort study) BMJ Volume 319 14 August 1999 pp412-5 (Incidence of weapon injuries not related to...'Thick' blood may increase stroke risk
...se in the lowest quarter. Only one small previous prospective study hasbeen reported on the relationship between...or and stroke, andARIC is believed to be the first prospective study ever to examine therelationship between factor VIIIc levels and stroke risk. A prospective st...Light alcohol use may protect against sudden cardiac death
...e American Heart Association. "This is the largest prospective study to look at alcohol consumption andsudden cardiac death in men and the first prospective study to find a reductionin sudden cardiac death from light drinking," says Christine M. Albert, M.D...Breast milk only for first four months helps protect against asthma and atopy
... and asthma in 6 year old children: findings of a prospective birth cohort study Delaying the introduction of milk other than breast milk until a child is at least four months of age may protect against asthma and atopy (a predisposition to various allergic reactions) in later childhood, say researchers from...Antibody solution may prevent adhesions after surgery
...in collaboration with Dr.Cheresh, in a randomized, prospective trial of adhesion prevention in womenundergoing laparoscopy for endometriosis and/or pelvic adhesive disease, Lesseysays. "If this antibody can be shown to be efficacious in preventing adhesionsin women, a larger multi-center approach will be organiz......ers and non-users of hormone replacement therapy: prospective cohort in Gothenburg, Sweden It is too early to recommend hormone replacement therapy (HRT) for the prevention of cardiovascular disease, concludes a Swedish study in this week's BMJ. Dr Kerstin R`dstr`m from Gothenburg University and colleagues ...