Stroke news tips for Friday, Feb. 8, 2002
...lly in young women, according to the largest known prospective study of arterial trauma and stroke. In this ongoing study, Canadian researchers examined 98 cases in which external trauma ranging from trivial to severe was identified as the trigger of ischemic strokes, the type of strokes caused by the formation...Researchers question conventional wisdom on 'mini-strokes'
..., Denmark. They used data from the community-based prospective Copenhagen Stroke Study to compare the risk factor profiles and short- and long-term outcomes of 154 individuals who had TIAs with 482 who had experienced mild strokes. If TIAs are just small strokes, one might expect similarities in the risk-factor...Abrupt changes in body position can trigger stroke
...ts acted as their own control group, making this a prospective case-crossover study. The relative risk of stroke among patients exposed to at least one trigger during a two-hour hazard period preceding the stroke was more than seven times higher compared to similar exposures during the same two-hour period the...Persistent mild depression in older adults may lower immunity and ability to fight off disease
...can Psychological Association (APA) is an 18-month prospective study of 78 older adults (average age of 72.5 years old) that compared those who suffer from chronic depression (22) and those who dont (56) on their ability to generate enough white blood cells to fight off an infectious agent. Participants were par...Blood lactate measurement could lead to earlier identification of patients for liver transplant
...tamol-induced acute liver failure and applied to a prospective validation sample of 107 patients. Predictive value and speed of identification were compared with those of the KCH criteria. In the initial sample, average lactate concentrations were significantly higher in non-surviving patients than in survivors ...UCSF reports promising results for organ transplantation in HIV-infected patients
... With the caveats that this data is retrospectivea prospective study is in processand very preliminary, we can say that the news so far is extremely good for those subjects who met the eligible subject criteria, said study co-investigator, Peter G. Stock, MD, UCSF associate professor of surgery. In addition, we ...Early breast and ovarian cancers detected in high-risk women
...linical Oncology. These results provide the first prospective evidence that BRCA testing can lead to interventions that result in the diagnosis of early-stage breast and ovarian cancers, said Dr. Kenneth Offit, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering and senior author of the study. ...Stopping statins may cause rebound that triples risk of death
...onary syndromes, says Hamm. A placebo controlled, prospective study appears unethical to test this hypothesis. That is why we preformed this retrospective analysis. Three drugs accounted for 94.5 percent of the statins prescribed for the patients: simvastatin, marketed as Zocor (50 percent), lovastatin, known ......ardioprotective effects have not been confirmed in prospective clinical trials in women with established heart di...ated to findingsof estrogen replacement therapy in prospective clinical trials, understanding the role of estrogen in the pathogenesis of the calcified, atheroscle...Survival benefit for rheumatoid arthritis patients treated with methotrexate
...s with rheumatoid arthritis, conclude authors of a prospective US study in this weeks issue of THE LANCET. Rheumatoid arthritis is a chronic inflammatory disease which results in reduced life-expectancy and is associated with cardiovascular disease, infection, and cancer. Low-dose methotrexate is the main choice...American Thoracic Society Journal news tips for April (first issue)
...CENTRATIONS RELATE TO ASTHMATIC DISEASE The first prospective epidemiologic study to demonstrate a relationship between cat allergen concentrations in the home and asthmatic disease among sensitized women was carried out in458 Boston, Massachusetts, mothers. To participate, the women had to suffer from doctor-...Simple blood test may be able to predict risk of preeclampsia
...rom the Massachusetts General Hospital (MGH). The prospective study found that women who eventually developed pr...y is part of the MGH Obstetrical Maternal Study, a prospective study of more than 4,500 women that seeks to identify risk factors for hypertensive disorders of pre......as occurred. Mark H Tuszynski reviews one of these prospective therapies: growth factor gene therapy for Alzheimers disease, an approach that is currently the subject of a phase I clinical trial. 2. Within the past 12 months, patients with multiple sclerosis have received intracerebral implants of autologous mye...Other highlights in the April 17 issue of JNCI
...versity of Oxford analyzed data from nine previous prospective studies on sex hormone levels in 663 women who developed breast cancer and 1765 women who did not develop breast cancer. None of the women were taking hormone replacement therapy at the time of analysis. Key and his coworkers found that women with t...Highest sustained virologic response in treatment of Hepatitis C ever reported in prospective study
...response (SVR), the highest SVR ever reported in a prospective trial for a pegylated interferon using an intent-to-treat (ITT) analysis, according to Dr. Donald Jensen at Rush-Presbyterian-St. Luke's Medical Center. SVR refers to a patient's continued undetectable serum hepatitis C (HCV) RNA levels six months af...USC researchers find ozone lowers sperm counts
... like to do another study of sperm qualitythis one prospective rather than retrospective, and looking at sperm samples from a number of major cities known to have significant increases and decreases in ozone levels, such as New York and Mexico City. "Im really starting to branch out," she says. "This is such a n...High-dose interferon beta-1b for multiple sclerosis patients
...0 mcg interferon beta-1a once weekly'. In a 2-year prospective study, 188 patients with relapsing-remitting MS were randomised to receive either interferon beta-1b or interferon beta-1a. Over 2 years, 51% of individuals administered interferon beta-1b remained relapse-free compared with 36% given interferon beta...Firstborn: First risk for heart disease?
...his relationship, he adds. Researchers conducted a prospective study of 348 people with CHD who had been admitted to the Cardiovascular Rehabilitation Unit of Fondazione Don Carlo Gnocchi in Milan. They also looked for other risk factors linked to being firstborn. They recorded birth order, age, gender, family...Tired and angry? Both emotions may predict heart attacks
...Risk in Communities (ARIC) Study. ARIC is a large prospective study of cardiovascular disease and its risk factors conducted in four U. S. communities: suburban Minneapolis, Minn.; Washington County, Md.; Forsyth County, N.C.; and Jackson, Miss. From 1990-98, researchers followed 12,453 men and women who were b...UT Southwestern gerontologist offers ways to find the right nursing home
...r at Dallas said consumers who conduct research on prospective facilities and discuss all options with family mem...inary research as possible, they should visit each prospective facility. If the facility has an odor or looks unkempt, or if some residents appear to have been una...