Comprehensive gene profiles hold promise for improving outcome of pediatric leukemia
.... If the initial accuracy findings are proven in prospective clinical trials, the chip technology might be able to replace the wide variety of laboratory tests now required to identify the specific subtypes of ALL. "That would greatly simplify diagnosis," Downing said. More importantly, the specific informatio...Duke leaders propose overhaul of health care and the practice of medicine
...he revised health-care system should be built on a prospective approach to medicine that emphasizes personal heal...ntegrated, comprehensive practice of genomic-based prospective medicine. The joint venture will capitalize on TCAG's state-of-the-art genomic sequencing and inform...News tips for Monday, Nov. 10, 2003
...nitial results are in from the first U.S.-approved prospective multi-center trial of "robotic assisted endoscopic coronary anastomosis" a minimally invasive closed-chest technique using robotic technology to perform micro-vascular coronary bypass surgical tasks. Twenty-four patients were randomized into either...Similar outcomes for atrrial fibrillationi patients with congestive heart failure
...ate, the researchers said. They added that further prospective studies should be conducted to weigh the mortality and quality-of-life issues for each of the two strategies for patients with atrial fibrillation and CHF. Duke cardiologist Sana Al-Khatib, M.D., presented the results of the Duke analysis today (Nov....News tips for Tuesday, Nov. 11, 2003
...mechanisms of this link are still undetermined. A prospective study of job stress and CHD assessed physical and ...rest survivors are not cognitively impaired. In a prospective study, 57 survivors from a group of 308 victims of out-of-hospital cardiac arrest underwent extensiv...Procedure cures atrial fibrillation
...ause heart enlargement. The Circulation paper is a prospective randomized trial involving 80 patients with the paroxysmal, or intermittent, form of AF, all of whom had experienced symptoms for years. Ever since Michel Hassaguerre, M.D. and his colleagues in Bordeaux, France, first described how AF is initiated ...Study shows promise for HIV-infected liver transplant recipients
...that the study should provide an impetus to larger prospective trials to study liver transplantation in HIV-infected patients with and without hepatitis C, and with standardized approaches to immune suppression, treatment of graft rejection, and both anti-hepatitis C and HAART therapies....Caterpillar Inc. bolsters Southern Community study with $1 million gift
...d die from) disease and those that do not. Such a prospective population-based study is the gold standard when it comes to identifying causes of disease, but to date, the major population-based studies have under-represented African-Americans. This is also the first such study to be conducted in the South. By n...Study to examine if new eczema drug may prevent future development of asthma
...ess, itching, cracking and bleeding. The six-year prospective study, funded by Novartis, will be conducted in two stages. During the first three years a double blind study will compare the safety and effectiveness of pimecrolimus in conjunction with corticosteroid therapy for flare-ups, vs. corticosteroid ther...Experimental drugs reduce neuron death in rats following insulin shock
... only a few insulin shock patients each year, so a prospective clinical study would likely require participation by dozens of sites. "I'm very enthusiastic about the clinical potential of this approach and have begun discussions with the Juvenile Diabetes Research Foundation about possible ways to get this orga...Senator Jon S. Corzine pledges support to NYU Child Study Center
...unded prevention trials and co-investigator on two prospective longitudinal studies of the development of conduct problems. She is currently the principal investigator on a ten-year, NIMH-funded prevention study with preschool-aged siblings of adjudicated youth as well as a U.S. Department of Education funded s...Physical activity key to maintaining independence say University of Pittsburgh researchers
...searchers. The study, which is the first long-term prospective study to prove the link between physical activity and function, appears in today's edition of Archives of Internal Medicine. The study followed 171 post-menopausal women who, from 1982 to 1985, were enrolled in a study to determine the effects of a r...3-D virtual colonoscopy is more sensitive than conventional procedure
...sity of Wisconsin Medical School in Madison. This prospective multicenter trial was conducted at the National Naval Medical Centers in Bethesda, Md., the Naval Medical Center in San Diego, and at Walter Reed Army Medical Center (Walter Reed) in Washington, D.C. Colon polyps are benign growths that may develop i...Surgery without radiation inadequate for DCIS, study reveals
...ancer Symposium on Wednesday, Dec. 3, is the first prospective study to evaluate the hypothesis that DCIS (a common type of breast lesion that is harmless as long as it is confined to the milk ducts) can be treated by removing it along with a wide margin of healthy tissue on all sides. If surgery alone proved to...Dietary fats may increase the risk of age-related macular degeneration
...ish and nut consumption reduced the risk. "In this prospective longitudinal study, we found that higher levels of dietary fat intake were associated with the progression of AMD to the advanced stages associated with visual loss," the authors write. "Specifically, higher intake of vegetable fat, and to a lesser ...Study suggests 1% risk of DVT for long-distance air travellers
...arch Institute of New Zealand and colleagues did a prospective study of long-haul air travelers to determine the frequency of symptomatic DVT and pulmonary embolism. Volunteers were given a D-dimer blood test before flying; increases in D-dimer concentrations were used to identify individuals who may have...Other highlights in the January 7 issue of JNCI
...ert.org/emb_releases/2004-01/jotn-bmn122903.php A prospective study of aspirin use and the risk of pancreatic cancer in women: http://www.eurekalert.org/emb_releases/2004-01/jotn-aum122903.php Active smoking, passive smoking, and breast cancer: Evidence from the California Teachers Study: http://www.eurekale...Cancer markers news backgrounder: Future of cancer diagnosis, treatment lies in tumor 'barcode'
...soon to be completed, will likely be followed by a prospective multicenter clinical trial to validate the proteomics approach to diagnosing ovarian cancer. "Our goal is to find and classify patterns of protein changes that we can use to detect and predict cancer and other diseases," Mills says. Subtypes of co...Taking vitamin D supplements lowers risk of multiple sclerosis
...of Public Health in Boston, MA. "This is the first prospective study to look at this question. "These results ...f low disease activity. Munger said that future prospective studies should measure the levels of vitamin D in the blood prior to the onset of MS....Normal aging versus Alzheimer's disease and the potential for prevention
... For example, by adding a cognitive arm to ongoing prospective observational studies in younger individuals, such as those related to risks for heart disease, a great deal might be learned with modest expenditures of funds. "We are already learning that there may be ways of maintaining general brain health that ...