African-Americans respond poorly to hepatitis C treatment
...ent in African-Americans. "This study definitively proves that the difference in response rate is not due to the higher rate of genotype 1 infection in African-Americans," said Andrew Muir, M.D., lead author of the study and an assistant professor of medicine at Duke University Medical Center. The results w...Jefferson scientists find new way to convert adult human stem cells to dopamine neurons
...becoming dopamine-producing neurons. If the method proves reliable, the work may ultimately lead to new therapies for neurological diseases such as Parkinson's disease, which is marked by a loss of dopamine-making cells in the brain. Developmental biologist Lorraine Iacovitti, Ph.D., associate director of t...Cognitive behavioral therapy combined with antidepressant effective in treating adolescent OCD
...ch therapists how best to conduct CBT. This study proves that the effective use of CBT alone, and a combination of CBT with an SSRI, will greatly improve the chance for decreasing the symptoms of OCD." Because most children who receive SSRIs continue to have clinical symptoms, The Center for the Treatment ...Protein not only aids nerve development, but promotes blood vessel growth, too
...ure human disease is at least 15 years away--if it proves viable, Li said. Li began studying whether Netrin-1 promotes blood vessel growth after discovering a vascular receptor for another neural guidance factor. Next, he wants to look at the roles of other netrins in blood vessel development and ident...... factors, including the lack of clinical data that proves its efficacy, continued evolution of technology, the fact that the procedure is not reimbursable by insurance and the continued need for bowel preparation. Researchers: Bowel Preparation Unnecessary with Virtual Colonoscopy (CT Colonogra...McMaster named Canadian Research University of the Year
...t used was based on both inputs and outputs, which proves we're not only attracting the financial support, but we're also producing quality research results. The momentum our research enterprise has gained is astounding. In the last 10 years, we've tripled our income, but more than that, we've recruited an...Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
...ment. However, if the theory of underconnectivity proves valid, therapies that stimulate brain areas to work in synchrony might also offer some benefit. Such therapies might stress problem solving skills and creative thinking, and attempt to foster flexibility in thinking. Dr. Just note...Jefferson scientists use gene therapy to rescue failing hearts in animals
...in a post-infarcted failing heart," he says. "This proves it could actually be a therapy since most of the previous studies of this type are aimed at prevention giving a gene and showing that certain heart problems are prevented. In those cases, heart problems are not actually reversed. This is a remarkabl...Re-analysis of large trials shows greatest benefit of chemotherapy in ER-negative tumors
... chemotherapy, Berry warns. He adds that the study proves that breast cancer patients of both hormonal types are being aided by clinical advances. "The prevailing wisdom has been that science has focused on ER-positive tumors, with development of SERMs and now aromatase inhibitors, but ER-negative patients ...Jefferson virologists coax HIV out of hiding
...and the body's immune system. If the new technique proves its mettle, the work could lead to improved treatments for HIV infection, and might be a step toward complete viral eradication. The Jefferson team reports its findings January 4, 2005 in the Journal of Clinical Investigation. Dr....Technology that could double the effectiveness of cancer drugs studied at Yale
...ave to start a whole new course of treatment if it proves ineffective." Mor's lab developed the Yale apoptosis assay based on a biological principle that when a drug is effective, it will induce apoptosis (cell death) in the cancer cell. If the cancer cell is resistant to a drug, apoptosis does not occur. M...New highly active agents against sandfly fever
...fantum , affects about 500 000 people per year and proves fatal if no treatment is given. Although drugs do exist for treating these diseases, they are not always effective, owing to the appearance of resistant parasites and to the toxicity of the products. Moreover, administration of the available treatmen...Study finds new designer drug is potent treatment for chronic myelogenous leukemia
...l trials at M.D. Anderson Cancer Center, and if it proves safe to administer, will be tested for effectiveness in CML patients at Dana-Farber and other sites. If the drug is effective, the next task will be to determine the optimal way of using it whether alone or in combination with Gleevec or as a follow...Chemists identify immune system mechanism for methamphetamine binges
...g to the researcher. "If the mechanism we proposed proves true in humans, then it will help explain why addicts go on prolonged binges, requiring more frequent intake and ever-increasing amounts of the drug in order to achieve a high," says Janda, who led the study with his former student, Tobin Dickerson, ...