EXANTA (TM), an oral direct thrombin inhibitor, significantly reduces risk of VTE in major OS
...sm (VTE) - proximal deep vein thrombosis (DVT) and pulmonary embolism (PE) - when treated with EXANTA, compared to standard prophylaxis with enoxaparin (40mg od). The relative risk reduction in major VTE was 67 per cent (1.8% vs 5.5%) for total hip replacement and 60 per cent (3.3% vs 8.2%) for total knee rep...Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control
...andomization, there were numerical improvements in pulmonary function, percent of days with no asthma symptoms ...ma control," said Steven A. Sahn, MD, professor of pulmonary and critical care medicine at the Medical University of South Carolina and one of the study's lead i...American Thoracic Society Journal news tips for November (second issue)
...rticosteroids in patients with chronic obstructive pulmonary disease (COPD) is associated with both a higher risk and more rapid onset of exacerbations, together with a significant deterioration in health-related quality of life. The Dutch researchers studied 244 patients who received a high dose of inhaled c...Satellite images predict hantaviral transmission risk
...orn disease that causes the often fatal hantaviral pulmonary syndrome (HPS) in humans. According to the researchers, satellite imaging detects the distinct environmental conditions that may serve as a refuge for the disease-carrying deer mice. Higher populations of infected deer mice increase the risk of HPS t...Results of first chronic treatment study with oral EXANTA(TM) (ximelagatran)
...after an initial deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Results from the THRIVE III* study ...c disease (including stroke, deep vein thrombosis, pulmonary embolism and myocardial infarction) each year in the EU and Japan.4 EXANTA is the first oral direc...High estrogen/progestin levels may reduce asthma severity, say Pittsburgh researchers
...ncreased hospitalizations for asthma and decreased pulmonary function during the premenstrual and menstrual pha...re low. Conversely, some women experience improved pulmonary function and a decrease in asthma exacerbation while taking oral contraceptives and hormone replacem...Common heart surgery potentially dangerous
...on, activate certain immune responses, and lead to pulmonary hypertension. It has a high positive electrical charge, while heparin has a high negative charge, so they "cancel" each other out, permitting the body to clear the combined agents quickly. "As much as protamine has helped treat patients with coronary...Early use of universal forms boosts informed consent among ICU patients
...sse Hall, M.D., professor of medicine and chief of pulmonary and critical care at the University of Chicago. "...an arterial catheter, a central venous catheter, a pulmonary artery catheter, or a peripherally inserted central catheter, lumbar puncture, thoracentesis (surgic...How 9/11 changed us: First-ever quantitative research documents the before and after effect
...atients with illnesses such as chronic obstructive pulmonary disease, congestive heart failure and asthma felt about their lives. Participants were asked questions about their mental health, levels of personal stress and feelings of control over their lives. "We saw an opportunity to gauge how this event chan...People only slightly more likely to die after episodes of stagnant air
... from respiratory problems and chronic obstructive pulmonary disease four days after an increase in air stagnat...delines if the air has been stagnant and you have pulmonary disease, its good to restrict your outdoor activities, said one of the researchers, Dr. Therese Mar ...American Thoracic Society Journal news tips for June 2003 (second issue)
...rated a limited short-lived improvement in patient pulmonary function. All participants in the trial were bein...rs observed a trend toward improvement in baseline pulmonary function test scores. In this controlled study, a smaller number of participants received a placebo...Cedars-Sinai Medical tipsheet for July 2003
...ent. This procedure can be done if the recipient's pulmonary artery pressure is normal because the heart will actually grow to accommodate the needs of the larger person. Mr. Rankin and his transplant surgeon are available for interviews....Tackling major risk factors simultaneously key to improving global health
...round 60%), lung cancer (72%), chronic obstructive pulmonary disease (60%), ischaemic heart disease (around 85%), and stroke (just under 75%). Removal of these risks would have increased global healthy life expectancy by over nine years from 56 to 65 years (ranging from 44 years (6%) in the developed countries...JCI table of contents, 1 August 2003
...the pathogenesis of asthma and chronic obstructive pulmonary disease" states Dr. Gabriele Grnig from St. Luke's Roosevelt Hospital in New York. Therapies designed to target enzymes or specific steps crucial to these pathways may be of significant therapeutic use in the treatment of other IL-13--mediated inflam...Oestrogen-replacement therapy from skin patches not associated with venous blood clots
...nted episode of VTE without a known cause (92 with pulmonary embolisms and 63 with deep venous thrombosis), and 381 controls matched for centre, age, and time of recruitment were studied. 21% of women with VTE and 7% of controls were current users of oral ERT, whereas 19% of women with VTE and 24% of controls ...Drug may eliminate transfusions in patients with blood disorder
...tes after the fetal hemoglobin level fell during a pulmonary infection. Another patient underwent splenectomy (removal of the spleen) six months after beginning treatment to treat hypersplenism, a condition marked by excessive destruction of one or more kinds of blood cells in the spleen. That patient receiv...Smoking causes half the tuberculosis deaths in Indian men
...st adult deaths in India involve vascular disease, pulmonary tuberculosis, or other respiratory disease. In the first major study of how smoking causes death in India, Vendhan Gajalakshmi from Chennai's Epidemiology Research Centre and her colleagues compared the tobacco smoking of 43,000 men (from both urban...American Thoracic Society Journal news tips for August 2003 (second issue)
...y were associated with a slower rate of decline in pulmonary function with aging, along with lower mortality ra...f physical activity on the longitudinal decline in pulmonary function among middle-age men (55 years average age at study start). They had complete data on phys...Workplace exposure a significant cause of severe respiratory disease
...ost of the 16 million cases of chronic obstructive pulmonary disease, or COPD, the finding that occupational ex...of occupational and environmental medicine, and of pulmonary and critical care. The research team's findings are being published in the September issue of the Eu...American Thoracic Society Journal news tips for September 2003 (first issue)
...mputed tomography (CT) imaging, when combined with pulmonary function testing (PFT) and developed into a compos...oung persons who had suffered little or no loss of pulmonary function from their illness. The investigators developed the new approach while assessing a new dru...