Bone marrowderived stem cells active in pulmonary fibrosis
...tion and deposition in the lung causing idiopathic pulmonary fibrosis may develop from cells derived from bone ... parenchymal lung fibroblasts. The authors induced pulmonary fibrosis in mice that had been altered with bone marrow labeled with a fluorescent green marker prot...American College of Chest Physicians to offer developing nations free access to medical journal
...atory diseases such as asthma, chronic obstructive pulmonary disease, and lung cancer have become a major burden for developing countries due to increasing tobacco use, occupational hazards, and environmental pollution," said Richard S. Irwin, MD, FCCP, President of the American College of Chest Physicians. "T...First US tuberculosis vaccine trial in 60 years begins
...over time. Also, BCG is not very effective against pulmonary TB, the most contagious form of the disease....Popular drug for chest pain may promote blood vessel damage
... Stamler, M.D., HHMI investigator and professor of pulmonary and critical care medicine at Duke. "Nitroglycerin is one of the most commonly used drugs in the western world," Stamler said. "Our findings raise concern that the drug may have deleterious consequences. The drug's long-term effects on patients shoul...Blood test could avoid inappropriate use of antibiotics for respiratory infections (pp 600)
... of patients), exacerbation of chronic obstructive pulmonary disease (COPD, 25%), and acute bronchitis (24%). Conversely, in patients with acute exacerbation of COPD, 60% positive sputum cultures for bacteria were found regardless of whether procalcitonin concentrations were high or low; however, those patient...Study compares clinical diagnoses and autopsy diagnoses in ICU deaths
...uding 21 cancers, 12 strokes, 11 heart attacks, 10 pulmonary emboli (blood clot in the lungs) and 9 endocarditis (inflammation of the heart valves). "With an autopsy rate of 53 percent, major diagnostic errors were identified for 31.7 percent of the autopsied patients, and the correct diagnosis would ha...Postmenopausal hormone therapy associated with increased risk for developing asthma
...for developing asthma, but not chronic obstructive pulmonary disease (COPD), according to an article in the February 23 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals. According to the article, because the incidence of asthma changes depending on a person's age, researchers sus...High blood pressure in the lungs a major risk for death in adults with sickle cell disease
...re in their lungs and that the condition, known as pulmonary hypertension, causes a much higher death rate in p.... A serious complication of sickle cell disease is pulmonary hypertension. Pulmonary hypertension is high blood pressure (not related to the pressure measured b...American Thoracic Society Journal news tips for March 2004 (first issue)
... generated from the coughs of patients with proven pulmonary tuberculosis (TB). The investigators developed a ...ing system to test 16 subjects with smear-positive pulmonary TB. Cough-generated aerosols were positive in 4 subjects (25 percent). The authors said that there...New index measures risk of death from blood clot
..., Ill. - Predicting the mortality of patients with pulmonary emboli (blood clots in the lung) may become possib... prognosis." Quantification of clot size with the pulmonary arterial obstruction index, called the CTPE Index, allows physicians to triage pulmonary embolism (P...Genetic mutation linked to infant lung disease
...thing and this work may provide insight into other pulmonary diseases." "These advances are made possible by the availability of the gene sequence provided by the human genome project and by close interactions among doctors and scientists seeking to understand these diseases," adds study co-author Jeffrey W...American Thoracic Society Journal news tips for April 2004 (first issue)
...ISK OF FRACTURE Patients with chronic obstructive pulmonary disease (COPD) who were current high-dose users of...iated with increased odds of suffering two or more pulmonary exacerbations that required either hospitalization or administration of intravenous antibiotics at h...American Thoracic Society Journal news tips for April 2004 (second issue)
...ymptoms appeared. The research group assessed the pulmonary function of 243 infants 1 month after birth. At age 11, 185 members of the cohort were reassessed, and 55 (28 percent) were shown to have had wheeze "ever." According to the authors, reduced neonatal lung function was associated with wheezing at age...Office spirometry significantly improves early detection of COPD
...proves early identification of chronic obstructive pulmonary disease (COPD), says a study published in the April issue of CHEST , the peer-reviewed journal of the American College of Chest Physicians. The study found that by using spirometry, the gold standard for diagnosing COPD, primary care physicians ne...New light shed on atrial fibrillation after bypass surgery
...t history of the disorder, and chronic obstructive pulmonary disease. Additionally, there were strong associations between the incidence of atrial fibrillation and the discontinuation of beta blockers and ACE inhibitors immediately after surgery, Mathew said. Significantly, the administration of beta blockers ...Estrogen offers no overall benefit for disease prevention in postmenopausal women with hysterectomy
...8 cases), and had no significant effect on risk of pulmonary embolism (85 cases) or colorectal cancer (119 cases). Corresponding results for composite outcomes were a significant increase (12 percent) in the risk of total cardiovascular disease, and a significantly decreased risk (30 percent) of total fractu...'Use it or lose it' warning rings true when it comes to exercise
...f a group of older adults with chronic obstructive pulmonary disease (COPD), a lung disease that kills some 120,000 people every year in the United States. All of the participants completed a 10-week exercise rehabilitation program, then were given a home exercise program to follow on their own. ...Study shows heart biopsy possible via arm catheterization
...take pictures of the heart arteries, to access the pulmonary artery in the lungs or the right side of the heart, or to measure blood pressures in certain blood vessels. Previous studies have shown that patients who have catheterization through the arm recover more quickly. When patients have catheterization th...American Thoracic Society Journal news tips for May 2004 (first issue)
...tients with moderate to severe chronic obstructive pulmonary disease (COPD. The investigators performed a double-blind, randomized crossover study on 19 COPD patients to investigate the degree of and potential relief from dyspnea during exercise. According to the authors, dyspnea is a hallmark symptom of COP...Radiologists back judicious use of CT pulmonary angio in women because of radiation dose to breast
...r alternatives before using CT in the diagnosis of pulmonary embolism in women under the age of 55 because of t...ease, and has become the gold standard for imaging pulmonary emboli, said Mark S. Parker, MD, associate professor of thoracic imaging at the Medical College of V...