Tag: "raloxifene" at medical news
V. Craig Jordan Will Present Results Of Raloxifene Breast Cancer Study At
American Society For Clinical Oncology Meeting
...ve that the estrogenic properties of drugs such as raloxifene
may also betargeted to prevent osteoporosis and heart attacks in postmenopausal women. Jordan is a professor of cancer pharmacology at Northwestern UniversityMedical School and director of the Breast Cancer Research Program at the RobertH. Lu...
New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
...cancer, only 11 or .21 percent of those assignedto raloxifene
developed the disease. However, like tamoxifen and estrogen,Cummings noted that raloxifene
does increase a woman's risk of developing bloodclots. He added that raloxifene
also reduced the ris...
Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy
...It was designed primarily toevaluate the effect of raloxifene
on bone mineral density (BMD) and spinalfractures ...the drug was well tolerated and women who received raloxifene
hadno higher incidence of uterine bleeding and breast tenderness than those whotook a placebo. The t...
Signal Pharmaceuticals Announces Positive Results In Preclinical Study Of Novel Drug Leads For Treatment Of Osteoporosis
... as Zeneca's tamoxifen(NolvadexTM) and Eli Lilly's raloxifene
(EvistaTM), also have anti-estrogeniceffects and t...rug leads were tested in parallel withestrogen and raloxifene
for their ability to inhibit bone resorption. The studyconcluded that Signal's drug leads were twic...
Osteoporosis Drug Evista (Raloxifene) Cuts Newly Diagnosed, Invasive Breast Cancer Risk By More Than 60 Percent
...findings show that the osteoporosispreventive drug raloxifene
(Evista®) reduces risk for newly diagnosed, in...er 10,000 postmenopausal women age 31 to 80 taking raloxifene
for morethan three years had a 63 percent reduction in the incidence of newly diagnosed,invasive bre...
UCSF study finds that an osteoporosis prevention drug reduces the risk of breast cancer by 76 percent in postmenopausal women
...d to receive either 60milligrams (mg) or 120 mg of raloxifene
per day, or a matching placebo. Of thesewomen, 2,572 received 120 mg of raloxifene
daily; 2,557 received 60 mg and oneplacebo tablet daily; and 2,576 received two placebo tablets dail...
Estrogen has antitumor activity in hormone therapy-resistant breast tumors
...nt breast cancer cells. Widespread use of the SERM raloxifene
for the prevention of osteoporosis has raised concerns that such women may eventually develop breast cancers that are resistant to raloxifene. Treatment of cultured raloxifene-resistant breast cancer cells with estradiol for 12 to 24 days inhibited ...
In a new observational analysis, Risedronate significantly reduced nonvertebral fracture risk
...x months for a bisphosphonate, nasal calcitonin or raloxifene
were excluded. All risk estimates were adjusted for age, sex, estrogen use, prior fragility fractures and a general morbidity indicator (number of concomitant medications). A six-month analysis was also done involving 7081 patients initiating thera...
University of Pittsburgh-led study confirms that Raloxifene protects post-menopausal women from invasive breast cancer
Pittsburgh, Feb. 13 -- The drug raloxifene
significantly reduces the risk of invasive breast ...Medical Association. "The MORE trial showed that raloxifene
reduces the risk of invasive breast cancer by 72 percent in women who took this drug daily for four ...
UCSD researchers find raloxifene is not associated with early cardiovascular harm
...earchers have found that the osteoporosis therapy raloxifene
HCl was not associated with early cardiovascular h...he study. The researchers found that four years of raloxifene
therapy did not significantly affect the risk of cardiovascular events in the overall MORE study pop...
Raloxifene following tamoxifen may offer no more reduction in breast cancer risk
A new study done in mice suggests that taking raloxifene
after 5 years of tamoxifen therapy may not further...prevent the growth of breast cancers. What's more, raloxifene
may stimulate the growth of endometrial tumors, conclude Ruth M. O'Regan, M.D., and V. Craig Jordan,...
Raloxifene after tamoxifen not beneficial
after five years of tamoxifen therapy does not pre...thwestern evaluated the effects on tumor growth of raloxifene
after tamoxifen treatment in mouse models of breast and endometrial cancers. They found that, afte...
Annals of Internal Medicine, tip sheet, July 2, 2002
...ast cancer avoid taking drugs such as tamoxifen or raloxifene
to prevent breast cancer. The USPSTF says that women at high risk for breast cancer and at low risk for serious side effects from the drugs should talk with their doctors about the risks and benefits of taking the drugs to prevent breast cancer. The ...
New research suggests drugs might help women at risk of breast cancer
...that the studies were small and shorter-term." The raloxifene
study, which focused on postmenopausal women with osteoporosis, showed a 76 percent reduction in relative risk. "These are pretty substantial effects and are worth considering," said the physician, a member of the UNC Lineberger Comprehensive Cancer ...
M. D. Anderson breast cancer prevention study reaches three-year mark
...ncer and uterine sarcoma; possible side effects of raloxifene
are blood clots in the legs or lungs. Women interested in enrolling in STAR may call the "STAR line" at 713-792-8064 or visit the Web site at www.mdanderson.org/star . For more information about breast cancer, call the National Cancer Institute's C...
Researchers compare drugs used to prevent osteoporosis
...journals. According to information in the article, raloxifene
helps prevent bone loss and increases bone mineral...mpared the effects of CEE and different dosages of raloxifene
on bone mineral density in 619 postmenopausal women (average age, 53 years) with prior hysterectomy ...
Study finds continued reduction in breast cancer incidence associated with longer use of raloxifene
...women with osteoporosis, 4 years of treatment with raloxifene
was associated with a 72% reduction in breast canc... effect of an additional 4 years of treatment with raloxifene
in the same group of women. In the CORE trial, more than 4,000 women who had been part of the MORE ...