Spinal repair pioneer to speak in NY on 20th Jan
...to UCL to attempt to transfer that technology from rats to humans, working with patients at the National Hospital for Neurology and Neurosurgery in London, and it is anticipated that the preparatory work to begin trials will be complete within two to three years. "For many years these injuries were consid...Controversial drug shown to act on brain protein to cut alcohol use
...ow shown definitively in experiments with mice and rats that Ibogaine does reduce alcohol consumption, and...aine reduced alcohol consumption. They induced the rats to consume alcohol in daily drinking sessions and then demonstrated that their drinking declined pre...Researchers identify the link between heart failure and weight loss
...ciation are poorly understood. Previous studies in rats by Patrick Delafontaine and colleagues from Tulane Medical University Center showed that administration of angiotensin II causes a marked reduction in body weight accompanied by a decrease in the levels of insulin-like growth factor-1 (IGF-1) in both...National Academies advisory: Report assesses health implications of perchlorate exposure
...based on the occurrence of a few thyroid tumors in rats exposed to perchlorate. The committee disagrees w...of thyroid tumors than rats, and therefore the way rats responded to perchlorate exposure is not a good indicator of how humans would react. In the past, hi...Jefferson scientists find zinc may help prevent esophageal, oral cancers
...ave found that zinc given orally to zinc-deficient rats reverses the development of precancerous condition...ancer development. In 2002, Dr. Fong reported that rats given a carcinogen while on a zinc-deficient diet developed esophageal cancer. Giving zinc prevented...Substance in urine predicts development of preeclampsia
...t sFlt-1 injected into the bloodstream of pregnant rats caused a preeclampsia-like illness. Last year, Drs. Levine, Karumanchi and their coworkers reported that high levels of sFlt-1 likely influenced the development of preeclampsia, by binding to PlGF and VEGF. Because they were bound to sFlt-1, the tw...New study shows early ritalin may cause long-term effects on the brain
... Rico, December 12, 2004 A new study conducted in rats by the National Institutes of Health (NIH) and McL...o examine the effects of early Ritalin exposure in rats on behavior and brain function during the later periods of life. "Attention-deficit hyperactivity di...Brain can be trained to process sound in alternate way, study shows
UCSF scientists have found that the brains of rats can be trained to learn an alternate way of proces... picture has changed. Polley trained two groups of rats to become " experts" at discriminating between very small differences in loudness -- an ability that...New technique scans electrical 'brainscape'
...orded and analyzed the electrical signals from the rats as the animals went through several days of sleep-wake cycling. Their analysis could detect activity patterns that marked waking, deep "slow wave" sleep and so-called "rapid-eye movement" sleep. Importantly, said Nicolelis, their analysis could...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...umor growth, increasing the survival of laboratory rats in pre-clinical studies. The study, published in ...mber of dendritic cells in the brain of laboratory rats with GBM. To evaluate whether hsFlt3L could shrink brain tumors and prolong survival, rats ...Sleep loss boosts appetite, may encourage weight gain
...re connected, however, is unclear. Sleep-deprived rats eat more than those allowed normal sleep. Several epidemiologic studies showed that people who sleep less are more likely to be overweight. One recent study found that those who reported less than four hours of sleep a night were 73 percent more li...Choosing the kind of fat to avoid obesity
...ion of leptin in primary cell cultures of fat from rats ", explained Ms Prez. This stimulating effect, in her view, is of great interest, "given that any strategy favouring the increase of leptin levels may well be beneficial for maintaining body weight during treatment for obesity and, thus, also obtain...Jefferson scientists use gene therapy to rescue failing hearts in animals
...2 weeks after they simulated a heart attack in the rats delivered the human S100A1 gene to the heart through the coronary arteries by injection of a genetically-modified common cold virus as a carrier. After about a week, they found the hearts began to work normally. In addition, the animals' heart muscl...Chronic back pain shrinks 'thinking parts' of the brain, study finds
...ord neurons undergo apoptosis -- cell death -- in rats with neuropathic pain. "Given that, by definition, chronic pain is a state of continuous persistent perception with associated negative affect and stress, one mechanistic explanation for the decreased gray matter is overuse atrophy caused by excito...Skeletal muscle cells could be source of stem cells for regenerating nerve tissue
...ry. These cells were cultured and transferred into rats with spinal-cord injury. The cells were able to organise skeletal-muscle fibres in the rats; furthermore, they differentiated into astrocytes (precursors of nerve cells) and neurons. Dr Alessandri comments: "Adult human skeletal muscle includes a pop...Abdominal fat decreases, insulin action improves when elderly take hormone
...of aging, according to the researchers. Studies in rats conducted by Holloszy demonstrated that DHEA replacement has a protective effect against both the insulin resistance induced by a high-fat diet and the decrease in insulin responsiveness that occurs with advancing age. "Earlier human studies indicat...Doctors transplant ovary to woman's arm to preserve fertility
...g hormone, have demonstrated ovarian protection in rats but conflicting data in nonhuman primates. Cryopreservation of embryos has been successful, but there have been no reported successful cryopreservation and transplantation of oocytes or primordial follicles, which are necessary for future fertility. ...New brain cells develop during alcohol abstinence, UNC study shows
...odel of chronic alcohol dependence, in which adult rats were given alcohol over four days in amounts that produced alcohol dependency. The study is in the Oct. 27 issue of the Journal of Neuroscience. In 2002, Dr. Fulton T. Crews, Bowles Center director, and Bowles Center research associate Dr. Kim Nixon ...The anti-arthritic effects of bee venom
... rat treated to induce inflammatory arthritis. For rats with advanced RA, treatment with bee venom at very low doses resulted in dramatic reductions of tissue swelling and osteophyte formation on affected paws. "Although the issue for determination of an effective dose is needed for further study," observ...FOSRENOL (R) maintains bone health status of end-stage renal disease patients
...hed during the period studied. In studies in mice, rats and dogs, lanthanum concentrations in many tissues...lanthanum in humans after oral administration. In rats and dogs, the mean recovery of lanthanum after an oral dose was about 99% and 94% respectively and w...