UCI center finds perchlorate may be acceptable in drinking water at higher levels
...ers may affect the fetus and newborn. Treatment of rats with other chemicals that result in chronic lowering of thyroid hormones has been shown to produce thyroid gland tumors. "Clearly more research should be conducted related to exposure to perchlorate, particularly with pregnant women and other suscept...UCI Tobacco research center reports why teens are most vulnerable to smoking addiction
...icotine causes changes in the adolescent brains of rats after just one exposure. Teens with ADHD may turn to smoking as a form of self-medication. Programs designed to prevent teen smoking have the greatest positive economic impact of all smoking-cessation efforts. People with negative moods or natural...New compound may act to keep thyroid activity in check
...hat the compound occurs naturally in the brains of rats and guinea pigs, and subsequently in the brains, heart, liver and blood of adult mice. The prediction and ultimate discovery of T1 amine followed on the heels of a previous discovery made in the Grandy laboratory. "For us, when we find a new receptor...New research suggests two brain areas critical for short-term memory
...orded activity in the hippocampus and subiculum as rats performed a memory task. The results showed that b...hey do it at different times. For the memory task, rats were randomly presented either a "right" of "left" lever. With food as an incentive, the rat pressed...Researchers invent way to determine optimal conditions for spinal cord nerve regen in lab animals
...nerated healthy spinal nerve endings of paralyzed rats using an implantable scaffolding. The scaffolding is referred to as a "biodegradable spinal graft." Mayo Clinic's experimental scaffolding consists of several innovations. It uses polymer chemistry to create a biodegradable material that can be molde...Patients with uncontrolled epilepsy have low levels of fatty acids
... "We looked at prior studies of animal models of rats with epilepsy and low levels of DHA," says Thomas ...tor of the Emory Epilepsy Center. "By giving these rats more DHA, it made it more difficult for them to have seizures. We are now exploring a similar connec...Study: New neurons can get out of spinal cord
...s axon-repelling effect. So the team implanted the rats with a pump to drip these myelin "de-squelchers" in the vicinity of the animals' spinal cords. As a result, some motor neurons extended themselves through the cord. To try to coax the new axons to finish their journey to muscle, the team now is expe...The preference for sweetened foods may decline after exercise
...erent concentrations of sucrose (sugar). Ten male rats were individually housed in a cage equipped with t... study 2). The bottles were arranged enabling the rats to drink both water and the sucrose solution at will. The rats ran on a treadmill at 30 m/min for tw...Is there a relationship between repeated pregnancies and increased cardiovascular disease?
...sted of seven to eight-month old female Long Evans rats which had previously undergone five pregnancies, b...continuously monitored in both groups of conscious rats in a stress-free environment. On the day of the experiment, baseline blood pressure was recorded fo...Estrogenlike drugs may eventually help postmenopausal women with weight gain
...e and body weight. Scientists, who commonly study rats that have had their ovaries removed (ovariectomize...oids that occurs at menopause, have found that OVX rats eat more and gain weight more rapidly than sham-opEαted control rats. Estrogen replacement redu...Calorie restriction drastically reduces risk of heart attack, stroke and diabetes
...ack, stroke or diabetes." Research on mice and rats has shown that stringent and consistent calorie restriction increases the animals' maximum lifespan by about 30 percent and protects them against cancer. This study is the first to examine individuals who have been on calorie restriction diets for a ...Green and black tea polyphenols consumption results in slower prostate cancer cell growth
...en found in the prostate and many other tissues in rats and mice after chronic consumption of green tea polyphenols in drinking water. Dr. Susanne Henning, UCLA Center for Human Nutrition, says the UCLA research team - a combination of nutrition scientists and urologists - focused on the possible effect ...Cell research uncovers intriguing clues to 'Trojan horse' gene in HIV infection
...n HIV infection. Closely related genes in mice and rats act against apoptosis. By dubbing the gene HALP, w...elpful and harmful roles. Highly similar genes in rats protect cells when blood circulation is interrupted. HALP may similarly exert a beneficial effect in...Animal model, new grant, propel UB researchers forward in search for tinnitus treatment
...ders and Sciences and a member of the center. The rats were trained to drink from their water dispenser d... licking during the quiet interval, indicating the rats were hearing a phantom sound. The high dose of sodium salicylate produced behaviors in quiet that w...New information about heart enzymes could lead to better treatments
...I, a hormone that promotes remodeling. By studying rats after heart attacks, the investigators learned mor...eted medications. The investigators studied rats with normal blood pressure. Three groups of rats had surgery to simulate a heart attack. These anima...Study finds nerve damage can affect opposite side of body
...how cutting a major nerve in one paw of a group of rats resulted in a significant decrease in skin nerve e...Brown describe their experiment in three groups of rats an experimental group in which the tibial branch of the sciatic nerve was cut in one hind paw and t...Norepinephrine important in retrieving memories
...l. Using mutant mice lacking norepinephrine and rats treated with drugs that block some norepinephrine ... as previously hypothesized by others. Mice and rats went through learning tasks that employ different brain regions: the hippocampus, which governs spat...Early life exposure to environmental agents predicts adult tumors in animals
...ion for Cancer Research, the scientists found that rats susceptible to developing uterine tumors inevitabl... Cook, Walker and a team of other researchers used rats genetically susceptible to developing uterine leiomyoma, the same kind of benign fibroid tumors that...Single cocaine exposure boosts both drug craving and avoidance
...received one of two drugs or a placebo. Before the rats were introduced to the training environments, they were injected with a dose of cocaine. They were then placed in one chamber or the other. One group was then injected with morphine over a two- to four-day period, while another group received a relat......nt called decorin into the damaged spinal cords of rats suppresses key molecules that block nerve regenera...y infused decorin directly into the injury site in rats with a mini-pump system, which used silica cannulas 160 microns in diameter. Because the cannulas we...