Antibiotic provides promise in treatment of spinal cord injuries
...oss. Administering the antibiotic, minocycline, to rats within the first hour after a paralyzing injury has been shown to reduce this tissue loss and ultimately enable more hind-leg function, the ability to walk with more coordination, better foot posture and stepping, and better support of body weight th...Study moves in on why astronauts suffer bone loss
...g, allowing it to move anywhere on the floor), the rats moved around, groomed, ate and otherwise managed w...ications of stress in either the skeletal unloaded rats or their untethered companions. In order to be able to follow IGF-1 pathways, the team used a specia...Exercise sharpens focus, decision-making among aging adults
...ions." Results of aerobic-intervention programs in rats and mice regularly show biochemical changes, particularly in the production of a molecule known as brain-derived neurotropin factor, which serves to protect the brain and increase the connections between neurons and promote neurogenesis, he said. The...Hormone released by bone marrow cells may hasten recovery from brain injury
...d following transplant into animals. Furthermore, rats suffering from stroke or other traumatic brain inj...ts of BNP from bone marrow cells transplanted into rats with strokes and spinal cord injuries....A little stress may go a long way toward boosting skin's immunity
COLUMBUS, Ohio A series of studies in rats and mice suggests that short bouts of stress incre...dies, researchers compared the immune responses of rats and mice that were restrained for two hours immediately before exposure to the antigen to control an...Cool brain opens stroke treatment window, say Stanford researchers
...after a stroke. What's more, cooling the brains in rats slowed the neurons' demise, giving researchers mor...erg's and Sapolsky's groups have shown that giving rats a form of gene therapy within 90 minutes after a stroke can help brain cells survive. The gene they ...Popular drug for chest pain may promote blood vessel damage
... about its potential to cause long-term injury. In rats treated with nitroglycerin for a period of three d...dilating blood vessels. The nitroglycerin-tolerant rats exhibited a significant decline in activity of mitochondrial ALDH-2, the enzyme critical to nitrogly...Gene therapy technique could aid islet transplants for diabetes, says Pittsburgh study
...c islet transplant system, using islets from Lewis rats and transplanting them into Sprague Dawley rats (this is similar to transplanting islets from one human donor into a different recipient). They also...Estrogen makes the brain more vulnerable to stress
...atry. The researchers exposed male and female rats to different levels of stress and then tested them...exposure to a moderate level of stress, the female rats were impaired, but the males were not, suggesting that females were more sensitive to the effects of...Brain reverberations during sleep
...ned the neuronal firing patterns recorded when the rats initially explored the new objects reappeared for up to 48 hours after these objects were removed. This reverberation of neuronal activity that they recorded was most significant during slow-wave sleep (a state that accounts for nearly 40% of a rat's...Brain receptor switches addiction on, off
...y, however, that return to a non-addicted state in rats has been reduced to a matter of hours, says Laviol...ame anatomical pathways that we're manipulating in rats also exist in humans so we hope that this will be applicable to human drug addiction as well," he sa...Evidence that memories are consolidated during sleep
DURHAM, N.C., -- By exposing rats to novel objects and measuring their brain signals... in October 2003. The researchers next exposed the rats to four kinds of novel objects in the dark, since largely nocturnal rodents depend on the sense of t...Yesterday, today and tomorrow: Mount Sinai researchers are making sense of episodic memory
... examined cellular activity within the brain while rats searched for food in a maze where the starting and... cells showed something very interesting while the rats performed the task. Some cells signaled location alone but others were additionally sensitive to rec...Synthetic progestin damages, estrogen protects blood vessels in animal model
...trogen prepaparations and oral contraceptives, the rats had visible damage to the periphery and brain blood vessels, endothelial and smooth muscle damage, inflammation and blood clot formation and impeded blood flow. These vascular reactions to synthetic progestin can lead to increases in heart attacks, b......in two rat models of cholestasis. In both models, rats that received the agonist showed significant reductions in serum markers of liver damage accompanied by improvements in liver histology. Treatment with the FXR agonist increased expression of the bile transporters, bile salt export pumps, and multidr...Outstanding UCLA undergraduates present research
...s researching how the immune system is impaired in rats whose pregnant mothers consumed alcohol. The thymus is significantly smaller in these rats, Lerner said. "Research and class lectures complement each other," Lerner said. "I learn techniques in class that I use in my research. Dr. Taylor is always a...Experimental drugs reduce neuron death in rats following insulin shock
...ain cell cultures derived from mice, as well as on rats subjected to induced hypoglycemic coma. In the cel...n goes into hypoglycemic shock. In one experiment, rats were held in hypoglycemic comas for 30 minutes before being rescued by glucose injections. Some of t...Buckwheat may be beneficial for managing diabetes
...glucose levels, the researchers studied a group of rats (approximately 40) with chemically-induced diabete...glucose properly. Under controlled conditions, the rats were given a single dose of either buckwheat extract or a placebo and their glucose levels were subs...Fosrenol shows significant reduction in serum phosphate in Chinese end-stage kidney disease patients
...ed by a variety of animal species, including mice, rats and dogs, at plasma exposure levels substantially ...e studies, lanthanum carbonate was administered to rats (n=120) and mice (n=100) by oral gavage throughout their lifespans and to dogs (n=8) by capsule (52 ...Blocking immune response to spinal cord injury can improve chances for recovery
...damage spinal tissue and nerve fibers. In tests on rats with induced spinal cord injuries, Keirstead and L... in T-cell counts and spinal damage. The untreated rats showed increased T-cell levels and greater secondary tissue damage. In further tests 14 days after t...