Anti-inflammatory drugs speed brain recovery in Stanford animal study
...nford University School of Medicine. Their work in rats suggests that common anti-inflammatory drugs relat... and in rats. First, she injected a substance into rats that is known to cause inflammation. Compared with rats that received a placebo injection, those tha...Stem cells from human peripheral blood protect against acute stroke in rats
...onal recovery when transplanted into the brains of rats with strokes, report researchers from the Universi...ury, was 30 to 35 percent less in HPB-transplanted rats than in the control animals. The researchers conclude the preliminary findings support the investig...Nicotine metabolite shows promise for improving memory, protecting brain cells
...model for studying antipsychotic drugs: laboratory rats given schizophrenic-producing drugs that block the natural filtering capabilities of the brain. Normally rats, or people for that matter, would be startled by a loud noise. But if a less intense noise precedes it, over time, the rodents will be less ...Repetitive work tasks linked to bone damage
...ms of WMSDs, the researchers analyzed behaviors in rats such as decreased movement performance and task avoidance. "These behaviors increased according to the rate of repetition. The higher the repetition, the more severe the symptoms," said Barr. While the researchers were not surprised by the nature of...Nicotine metabolite may improve memory, protect against disease
...havioral functioning. The researchers implanted 46 rats with small minipumps that dispensed either 3 or 6 ...m a group of rats. They then treated some of those rats twice daily with a dose of nicotine that produced blood nicotine levels equivalent to those seen in ...Bone marrow stem cells build new circulation to lungs
...s Hospital, removed vascular progenitor cells from rats bone marrow. The cells were cultured for five day...s, then injected into the pulmonary circulation of rats with PAH. A second group of rats with PAH received skin fibroblasts (cells), while a third group, w...Universal bone marrow cell spurs growth of vessels and heart muscle
... damage, the researchers induced a heart attack in rats and introduced the hBMSC into heart tissue around ...nction. Heart function after 28 days was better in rats that received the hBMSC than in the rats that received total bone marrow cells or saline. The transp...Antidepressants decrease chronic pain by inhibiting TNF production in brain, UB researchers find
...ctor (TNF) in the brain. This study, conducted in rats as an animal model, builds on their earlier publis...ain, as well as to eliminate pain, was the same in rats as in humans, suggesting the results may apply directly to humans. "Our findings should contribute ...Environmental influences found to have role for development and function of the pain system
...ined the development of a withdrawal reflex in 161 rats after a brief noxious heat stimulus to the tail. T... noxious stimulus. Anesthetizing the tail in adult rats did not alter the reflex. These findings indicate that this cross-modality adaptive response during ...Scientists map maturation of the human brain
... the adult brain. The researchers found that adult rats exposed to a social stress during adolescence (age...eriod might alter this pattern. A control group of rats was housed with their peers, and an experimental group of rats was housed individually during adoles...Exercise has a more powerful impact on the brain than previously thought
...), late-middle-aged, (15 month) and old (24 month) rats before and after various periods of exercise. "We found that the induction of BDNF in each age group rose significantly after one week of exercise," says Cotman. When all the groups were tested with a task that is used to assess levels of depression,...Coping behaviors linked to female chromosome
...dence for X-linkage in offspring of two strains of rats that exhibited differing coping behaviors. First-generation males but not females showed maternally derived coping styles, while second-generation females -- but not males -- showed significant differences in coping styles determined by their grandmo...Memory-enhancing drugs for elderly may impair high-level brain function
...KA is disinhibited in the prefrontalcortex of aged rats with naturally occurring working memory deficits. The researchers conclude that aging has diverse effects on different brainregions-specifically, decreasing PKA activity in the hippocampus andincreasing it in the prefrontal cortex. These observations...New study shows possible role of SERMs in future menopausal hormone therapy
...ment. The researchers treated different groups of rats with EM-652 and estrogen and measured the impact o...women," explained Dr. Labrie. "If our findings in rats are duplicated in women, this tissue-specific hormone replacement therapy could meet the most import...Whole tomato powder effective in preventing prostate cancer
...ad a lower risk of death from prostate cancer than rats fed diets containing pure lycopene or a standard diet. Moreover, the study found that rats that consumed fewer calories per day had a lower risk of prostate cancer, independent of the composi...Wild blueberries may help protect arteries, reduce risks from cardiovascular disease
...iovascular disease. The project is the first using rats fed blueberry diets to demonstrate a relationship ...ct cells. Wild blueberry consumption in laboratory rats has also been linked to improvements in memory and motor skills. At UMaine, Dorothy Klimis-Zacas, ...Researchers fly away from gravity on the 35th ESA Parabolic Flight Campaign
...al passengers on this week's flights are a pair of rats named Ariane and Apollo. However, they will not be aware of their free-fall. A medical team from the University of Bordeaux will perform some simple surgery on the anaesthetised rats. In this way, the team intends to investigate the feasibility of ca...Adolescent binge drinking produces tolerance to alcohol
...ulthood." Researchers used 135 male Sprague-Dawley rats for four experiments. On postnatal day 30 (the ro...e), pretreatment consisted of injecting all of the rats with 5.0 g/kg alcohol or saline every 48 hours for 20 days. For experiment I, 24 rats (12 pretreate...... Although the pituitary gland and ovaries of these rats still functioned normally, their brains had alread...t brains. However, an important difference is that rats still posses a significant number of oocytes after the fertile period, whereas in humans the supply ...The neighborhood matters: Packard Center scientists show cell environment is important in ALS
... with standard animal models of ALS. Those mice or rats carry a mutant human gene -- called SOD1 -- that triggers a rare, inherited form of the disease in people. In these models, every cell carries a mutant SOD1 gene. The animals typically slip into death by the time they're six to eight months of age. B...