Researchers identify novel treatment for polycystic kidney disease in animals
...ment of cysts and prevents kidney function loss in rats and mice, according to a Mayo Clinic and Indiana University School of Medicine study published in the October 2003 issue of Nature Medicine. Inherited diseases that cause the kidneys to develop fluid-filled cavities (cysts) are major causes of kidney......ntly reduced the size of a stroke. Scientists fed rats either a low-potassium (Low K) or high-potassium (...ge in 37 percent of the affected hemisphere, while rats on the Low K diet had 56 percent damage. The researchers believe potassium protects the brain by af...UGA, MCG study impact of long-term use of schizophrenia drugs
...ving the different antipsychotics daily to healthy rats at levels that mimic what patients receive for 180 days, or about one-fifth of the rodent's lifespan, to measure the long-term impact of these drugs. They will study memory function and eventually analyze brain chemistry, looking at how form and fun...Comfort-food cravings may be body's attempt to put brake on chronic stress
...s have identified a biochemical feedback system in rats that could explain why some people crave comfort f...amus to the adrenal glands glucocorticoids prompt rats to engage in pleasure-seeking behaviors, which include eating high-energy foods (sucrose and lard). ...Cranberries may help reduce stroke damage
...ke," she says. Neurons from the brains of several rats were collected for this study. After placing the n... Neto and her associates obtained brain cells from rats and exposed the cells to two specific conditions that commonly occur during stroke. In one condition...Early nicotine use may lead to lasting addiction, study finds
...amount of nicotine self-administered by adolescent rats to the amount used by animals first exposed during adulthood. Young rats showed nearly double the rate of nicotine use compared with those initially exposed as adults, the s...Black cohosh may reduce hot flashes by targeting brain's thermostat
...osh is estrogenic, the researchers used a group of rats whose ovaries had been removed. The rats were divided into different groups and each group was fed a different concentration of cohosh extrac...Rat study shows exposure to Ecstasy early in pregnancy induces brain, behavior changes
... Koprich, and their colleagues injected 8 pregnant rats twice daily with MDMA from day 14 through day 20 o...control animals. "Our findings show that exposing rats to Ecstasy at a time of prenatal development that correlates with the first trimester in humans may ...Hot pepper chemical links tongue to heart
...n of blood vessels and chest pain. One group of rats was treated with a capsaicin drug that would specifically bind and deplete the nerve containing the VR1 receptors. Another group, serving as controls, was treated with a placebo, or non-medicated, substance. The ones treated with placebo showed blood...Taking Ecstasy during pregnancy may cause brain damage, behavior problems in babies
...er in Chicago, demonstrated that fetal exposure in rats to the drug Ecstasy during a period analogous to t... day 20 of pregnancy. An equal number of pregnant rats were given sham injections of saline twice daily during the same period as a placebo. The most stri...Amphetamine or cocaine exposure may limit brain changes that occur with life experiences
...tructure and affect behavior. Now, new research in rats shows that exposure to stimulant drugs such as amp... step further. After the 20-day drug exposure, the rats were housed in a new environment for 3 to 3.5 months. Half of the drug- and saline-injected animals ...UCI researchers identify link between infant seizures
...nd that experimental prolonged febrile seizures in rats enhanced the number of receptors for endocannabinoids in the part of the brain important for memory and damaged by adult epilepsy. They also discovered that a single episode of febrile seizures was enough to cause a permanent increase in the number a...Did rats spread SARS in Amoy Gardens?
...this week's issue of THE LANCET proposes that roof rats could have been responsible for the spread of the ...n could have been passed from rat to man either by rats entering households and leaving infectious material in bathrooms and kitchens, or by contamination o...Rutgers scientists pinpoint brain cells involved in drug addiction relapse
...ed to be a good model of human addiction, in which rats were able to self-administer a specific drug.The a...ine was dispensed. At the end of three weeks, the rats had learned to press the lever when they heard the tone. Next, both the drug and the lever were r...UCI biomedical engineer receives $1.8 million grant
...s harvested from connective tissue in the tails of rats and human lung cells. Once created, the viable lung tissue will be approximately the size and thickness of a penny, and live on a specialized solution of salts, sugars and antibiotics. George's research team includes doctoral graduate students Justi...New compound that acts on peripheral receptors may be treatment for some nerve pain
Results of a new study in mice and rats show that a compound which acts on a specific type...y." The scientists tested the chemical on mice and rats with neuropathic pain, a complex chronic pain state resulting from nerve injury or disease. They fou...Cedars-Sinai researchers detail events that enable brain tumors to weaken immune system
...cause it causes the release of glucocorticoids. In rats that had their adrenal glands removed to reduce the production of glucocorticoids, the damaging effects were significantly less pronounced. This finding may also have implications for the way physicians currently treat swelling of brain tissue in pa...Fetal exposure to two chemicals cause of male reproductive disorders later in life
...the last 20 years and that linuron exposure in the rats led predominantly to a malformation of the epididymis.) The altered adult phenotype following in utero exposure to linuron is very similar to that produced by the antiandrogen DBP, with the exception of testicular lesions and alterations in feta...Vitamins C and E may enhance effectiveness of insulin for diabetes
...age often seen in untreated diabetes. Treating the rats with insulin alone improved high blood pressure somewhat and partially spared the sugars and proteins from the free radicals' assault. But it also added a new problem, as the free radicals turned their attack on nitric oxide, a ubiquitous molecule th...Tissue-engineered cells transmit electrical signals in animal hearts
...ICAGO, Nov. 17 Preliminary findings of a study in rats suggests that a person's own cells might one day r...art beating properly. "The cells have survived in rats for more than a year and they appear to have made connections with cardiac cells," says Douglas B. C...