Study suggests that tomboys may be born, not made
...ines, Ph.D., of City University in London "In both rats and rhesus monkeys, genetic female animals treated with testosterone during critical periods of prenatal or early postnatal life show increased levels of male-typical play behavior as juveniles." Hines and her co-authors note that girls with congeni...Mimicking brain's 'all clear' quells fear in rats
...al activity of neurons in the prefrontal cortex as rats were fear-conditioned taught to fear a tone by re....e., the louder this safety signal -- the less the rats froze. Animals that showed the most infralimbic activity behaved as if they had never been fear con...Animal studies prove hormone replacement therapy improves memory, report Pitt researchers
...ty of Pittsburgh School of Pharmacy. In the study, rats had their ovaries removed and some of the animals ...r ovaries removed with subsequent ERT outperformed rats on various tasks without ERT. The ability of estrogen to enhance performance was lost in animals tha......om the sympathetic branch of the nervous system of rats andinjected multiple abdominal fat compartments with molecular taggedpseudorabies virus. The replication of viral particles resulted ininfections occurring only along the chain of functionallyconnected neuronsof the PSNS from the fatty tissue to the ...JCI table of contents, November 4, 2002
...om the sympathetic branch of the nervous system of rats andinjected multiple abdominal fat compartments with molecular taggedpseudorabies virus. The replication of viral particles resulted ininfections occurring only along the chain of functionallyconnected neuronsof the PSNS from the fatty tissue to the ...American Thoracic Society news tips for November (first issue)
...ical animal data, they tested their ideas on 1,296 rats at varying doses of infectious agents. They found that regardless of the type of anti-inflammatory agents used, the drugs were more effective at a severity associated with higher death rates. The research appears in the first issue for November 200...Hibernating squirrels provide clues for stroke, Parkinson's
...f the compound to the animal model for stroke, the rats - which are not known to hibernate - looked sleepy in the hours following but recovered dramatically. In fact, at least in rats, the levels of endogenous peptide increased immediately following a stroke, which makes him suspect that the levels may al...Story tips from DOE's Oak Ridge National Laboratory Nov 2002
... a nearby receiver. Early testing using laboratory rats has provided encouraging results. [Contact: Nance Ericson] HOMELAND SECURITY -- Portable radiation analysis . . . First responders, customs inspectors and law enforcement personnel may soon have a new instrument to detect radioactive material at ai...Studies offer new treatment option to prevent kidney rejection
... poorer kidney filtration. This study followed the rats for five to seven days; the next step in the project is to follow them for a longer period of time. Inman also is interested in studies that suggest certain cholesterol-lowering drugs may improve renal function, and is launching another project to se...Rutgers study shows learning ability under stress still strong in Prozac-treated females
...Falduto and Sabrina Mendolia, studied adult female rats treated with the antidepressant Prozac and a control group that received no treatment. They found that after a stressful event, learning was impaired in the control group but not in the group treated with Prozac. The researchers also found that only ...New hope for vaccine to fight rheumatoid arthritis, other autoimmune diseases
...The vaccine reversed an arthritic-like disease in rats by mobilizing part of the immune system to protect joints under attack by other immune cells. The work was reported in two related papers in the September Journal of Immunology . Autoimmune diseases, in which the immune system attacks the body's own ...Long-term ERT in postmenopausal women with Alzheimer's may worsen memory
...rican Psychological Association (APA), used female rats to study the effect of ERT on memory. The findings...h Laboratories at the University of Arizona had 40 rats perform a water maze task to look at the interaction of two conditions known to exist within the bra...New drug stops stroke damage to brain
...archers reveal that the drug, when administered to rats either before or within one hour after the onset of stroke symptoms, stopped the damage that occurs during a stroke. According to the co-principal investigator, Dr. Michael Tymianski, senior scientist in the Toronto Western Hospital Research Institut...Prototype developed for ultrasonic patch to deliver insulin
...ds." Experiments with human skin and with live rats have shown that the new ultrasound patch delivers ... vessels. Smith notes, "Our experiments with rats show that an exposure of 20 minutes produced the same result as a 60-minute exposure. So, we are ho...Mothers who drink during pregnancy may increase children's cancer risk, study shows
...ilakivi-Clarke and her colleague found that female rats exposed to alcohol in utero developed breast tumors at a significantly higher rate; their study also showed that the female offspring had higher breast density, and more estrogen receptors--both of which have been linked to higher breast cancer risk ...Gene therapy success in the laboratory buoys hope for Parkinson's disease
...amic acid decarboxylase (GAD), into brain cells in rats that were made Parkinsonian. They saw a dramatic d...in the behavior and physiology of the Parkinsonian rats treated with the GAD-carrying virus compared to the Parkinsonian rats that did not receive the treat...Tiny nerves from the ribs may restore leg movement in spinal cord injury
...lled aFGF, partially restored hind leg movement in rats that had their spinal cords severed. "By using tin...pinal cord injury." Lin and his team found that 12 rats with severed spinal cords were able to move their hind legs again after treatment with both the aFGF...Antioxidant reduces brain damage in stroke model
... researchers blocked the middle cerebral artery of rats for 90 minutes. They then injected AEOL 10150 or a...royed by the stroke, 43 percent less than that the rats who received the placebo. "There is a significant arc of potentially salvageable tissue surrounding...New clues to help diabetes and hypoglycemia
...lled Neuropeptide Y (NPY). Studies using diabetic rats have shown the NPY levels in the brains of diabetic rats differ significantly to those of normal rats under conditions of low glucose. It was known that sp...UT Southwestern researcher studies causes, treatment of bipolar disease coupled with drug abuse
...udy results have shown that giving neuroleptics to rats increases cocaine self-administration while giving atypical antipsychotics decreases cocaine self-administration. "Since bipolar patients often self-medicate to alleviate stress-induced anxiety and manic and depressive symptoms with illicit drugs, an...