Tag: "receptors" at medical news
Scientist works on innovative treatments for brain tumors
...vantage of the unique presence of restricted IL 13 receptors
in glioblastomas as a treatment target," he said. ... identify other agents that will bind to the IL 13 receptors
besides IL 13. If they are able to find agents that are smaller than IL 13, more opportunities to de...
Drug that hinders blood vessel growth under study in ovarian cancer
...d angiogenesis. This particular medication targets receptors
on new budding blood vessels in an attempt to down-regulate them and prevent growth. If that process is shut down, the tumor should not grow or spread." A6 has been shown to inhibit cancer metastasis in animal studies and showed "encouraging res...
Studies underscore genetic involvement in nicotine addiction & aggressive hostility
...tions in Chrna4 could, by varying how the nicotine receptors
works, result in animal-by-animal variation in nic... humans. Understanding how genes change nicotine receptors
may foster better treatments. Stitzel says, "No single gene is going to be the sole determinant of ...
Marijuana ingredient may stall decline from Alzheimer's
... a similar age. They looked closely at cannabinoid receptors
CB1 and CB2 proteins to which cannabinoids bind, a... a dramatically reduced functioning of cannabinoid receptors
in diseased brain tissue, meaning that patients had lost the capacity to experience cannabinoids' pr...
Potential drug target for treating cocaine abuse found
...Dopamine signals pleasure and reward by binding to receptors
on the receiving neurons, after which it is reabsorbed for later use by a protein that transports it back into the sending neuron. But cocaine blocks the mechanism that transports dopamine, causing it to build up and send an unceasing message of plea...
Medication helps alcoholics control drinking
...nce the early 1980s. Naltrexone blocks the brain's receptors
for natural painkillers, known as opioids, which normally create the feeling of wellbeing associated with drinking. He explains that the benefits of naltrexone lie not so much in preventing a patient from having one drink, but rather in breaking the...
Impact of scientific advances on drug studies and membrane research to be explored
...hannels that allow proteins to cross membranes and receptors
that signal changing conditions of a cell's environment, to the molecular biology and genetics of the membrane processes leading to thermosensation and hearing. For a complete list of speakers, topics and the schedule, visit www.delange.rice.edu . T...
Johns Hopkins scientists receive presidential medals
...accomplishments range from the discovery of opiate receptors
in the brain -- work for which he shared the prest...ience have stemmed from Snyder's identification of receptors
for neurotransmitters and drugs, which led to clarification of how psychotropic agents act in the br...
Hypothyroidism associated with reduced breast cancer risk
... both conditions can be closely monitored. Nuclear receptors
for thyroid hormone and estrogen are part of the "superfamily" of receptors
that contribute to control cell growth and differentiation. Hormones must bind to this family of imp...
Transport system smuggles medicines into brain
...atoms. On reaching the BBB it binds to transferrin receptors
on the endothelial cells. Once the transferrin has bound to the receptor, a vesicle in the cell completely engulfs it. The transferrin then releases the iron atoms, which are brought to the brain by another protein. A major advantage of this transpor...
Love me; Love my jokes
...e between producers (those who make you laugh) and receptors
(those who laugh when someone cracks a joke)," said Bressler. "Women choose men who produce humour 62 per cent of the time; conversely, men choose women who appreciate their humour 65 per cent of the time." Bressler also found a marked difference whe...
Sex hormone metabolite reduces stress, anxiety in female rats
...an artificial progestin that binds to progesterone receptors
but does not metabolize into the progesterone meta...otransmitter in the central nervous system, at its receptors
throughout the brain. This mechanism, Toufexis said, likely accounts for progesterone's blunting eff...
UCLA brain scientists crack mystery of how alcohol causes intoxication
...rst to identify how the gene variation alters GABA receptors
-- specific sites targeted by chemicals from the brain cells -- making them more responsive to very low levels of alcohol. Alcohol enhances the GABA receptors' influence on brain cells, slowing the cells' activity and ability to communicate. IMPAC...
Common antidepressants lower effects of tamoxifen in many women
...ecules are extremely powerful at blocking estrogen receptors
and thereby exert a cancer-inhibitive effect," said Dr. Flockhart. "We have withheld clinical recommendations, because at this point we don't have final data," said Dr. Flockhart. The study makes clear that knowledge of a drug's ability to inhibit C...
A site for sore eyes: New target for allergies found under the eyelid
...that drugs that block the binding of MIP-1a to its receptors
could help in the treatment of ocular allergy and ...that drugs that block the binding of MIP-1a to its receptors
CCR1 or CCR5 may have therapeutic value in the treatment of ocular allergy and possibly other allerg...
USC/Norris oncologists test new front-line therapy for pancreatic cancer
...ing with vascular endothelial growth factor (VEGF) receptors
on blood vessel cells, as well as platelet-derived growth factor (PDGF) receptors, which are found on special cells that provide the external structure for blood vessels. Encouraging results have already been reported from a phase II trial of the com...
Gene vaccine protects mice against development of Her2/neu breast cancer
...ats this kind of breast cancer by "plugging" these receptors
with a monoclonal antibody, but this treatment "produces only a passive and transitory immune reaction," Lachman said. "This vaccine, however, like many that treat microbial infections, appears to create a memory in the immune system that produces a ...
Mice with depression-like behaviors reveal possible source of human depression
...searchers engineered mice that lose glucocorticoid receptors
from their forebrains, specifically from the corte... the engineered mice indicates that glucocorticoid receptors
in the cortex and hippocampus--forebrain regions associated with higher thought, memory and emotion-...
Novartis announces collaboration with Bayer for EMSELEX
... the treatment of OAB that is selective for the M3 receptors
in the bladder, with proven efficacy, good tolerab...detrusor contraction, whilst sparing the M1 and M2 receptors
that are located in various body organs, including the brain and heart. EMSELEX has been shown to ef...
How platelets help cancer invade other tissues
...ediated inhibition of platelet-derived LPA and LPA receptors
present on tumor cells may be another promising target for reducing or preventing bone metastasis....
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