Newborns with heart defect have low blood flow in brain before surgery
...e infants' cerebral blood flow before surgery. The reduced blood flow was associated with abnormal features in the newborn brain, according to pediatric neurologist Daniel J. Licht, M.D., who led the multidisciplinary research team at Children's Hospital. "Some of the neurodevelopmental problems that these c...Transplanted bone marrow cells reduce liver fibrosis in mice
...ed blood marrow cells degraded collagen fibers and reduced liver fibrosis, exhibiting strong expression of matrix metalloproteinases (MMPs), especially MMP-9. "The reason for the strong expression of MMP-9 is still unknown," report the authors, but report that it was somehow related to the migration of the b...Sleep loss boosts appetite, may encourage weight gain
...ep. But we are finding that people tend to replace reduced sleep with added calories, and that's not a health...red by changes in hormone secretion, which in turn reduced sleep quality. A 2001 study demonstrating that inadequate sleep could foster insulin-resistance, a...More than half of relapsed CLL patients respond to two biologics with chemotherapy
...t of leukemia in 11 patients (35 percent) has been reduced by at least half, says William Wierda, M.D., Ph.D., assistant professor of medicine in the Department of Leukemia. "An overall response rate so far of 55 percent is very encouraging in this heavily pretreated population of patients that had limited t...Does the lack of sleep make you fat?
...he recent rise in obesity may be partly due to the reduced amount of time we spend asleep, according to new r...d that people who slept for shorter durations have reduced leptin and elevated ghrelin. These differences are likely to increase appetite and, in societies wh...Grab 'n' go breakfast better serves middle school children
... but better provide for those entitled to free and reduced price meals, according to Penn State researchers. ...d obesity. However, for those entitled to free or reduced price breakfast, skipping breakfast may be preferable to being singled out by walking to the cafeter...SIDS risk linked to lack of experience with tummy-sleeping
...ained decreases in carbon dioxide. Head lifts also reduced carbon dioxide levels, but the decreases lasted only as long as the baby's head was raised. The researchers suggest that babies learn through experience which head movements decrease the discomfort associated with breathing high carbon dioxide level...Two days of post-surgical pain relief now possible with just one shot
...poDur demonstrated lower pain intensity scores and reduced need for rescue medication. In these trials, efficacy was assessed for at least 48 hours and safety was assessed for up to 30 days after DepoDur administration. DepoDur is indicated for single-dose administration by the epidural route, at the lumbar...Novel drugs help solve Gleevec resistance
...4825, Talpaz reports. Side effects, which included reduced red and white blood cells and platelets, have been well tolerated, he says. Talpaz expects the efficacy of BMS-354825 to increase as more patients are enrolled and tested. "We haven't reached anything close to the maximum tolerated dose, yet we still...Ongoing transfusions needed to avoid strokes in children with sickle cell disease
...carrying red blood cells in these at-risk children reduced stroke risk by 90 percent. That study, which began in early 1995 and followed 130 at-risk children with sickle cell disease age 2-16 at 14 sites in the United States and Canada, also was halted early in September 1997 by the NHLBI because of the obvi...VGTI researchers help uncover why aging reduces immune system function
...mice, a less diverse population of CD8 T cells and reduced ability to fight disease. In addition, the scientists were able to show that increasing TCE cells in a normal, healthy mouse reduces that animal's ability to fight disease. "While this work is still in the early stages, we think it might be of gre...New drug protects against the hardening of arteries
...rrently used to treat type 2 diabetes. GW7647 also reduced weight gain, and insulin and lipoprotein levels. I...y Li and colleagues by which lipid accumulation is reduced by these agonists, thereby giving us a greater understanding of the roles of PPAR family members in ...Drinking water could be beneficial to patients with low blood pressure
...d pressure and symptoms of low blood pressure, was reduced while standing. Professor Mathias adds: "While autonomic failure itself is generally not life threatening, it can have a significant impact on an individual's quality of life. People with low blood pressure caused by autonomic failure are at a greate...Jefferson scientists use gene therapy to rescue failing hearts in animals
...efferson Medical College, "because this protein is reduced in heart failure, simply bringing the protein leve...s by other researchers showed that the protein was reduced by as much as 50 percent in patients with heart failure. A few years ago, Dr. Koch and his co-worker...Higher incidence of rejection following early steroid withdrawal
... have reported that early withdrawal from steroids reduced the incidence of these side effects, but that rejection increased, although it could be controlled with steroid pulse therapy (in which high doses of steroids are administered intravenously for a short period of time). The current multicenter study w...Small social circles tied to heart disease death in women
...els, lower rates of smoking and other factors that reduced their risk for coronary disease. Women with larger social networks also showed fewer signs of artery blockage during the four-year study. "The overall magnitude of the social network effect rivaled or exceeded that of more commonly considered biomedi...Other highlights in the December 1 JNCI
...' Relation to DNA Repair and Malignant Melanoma A reduced capacity to repair UV-induced DNA damage has been ...cus may predispose people to melanoma because of a reduced ability to repair sun-induced DNA damage in addition to the loss of tumor suppressor function. Conta...Study finds continued reduction in breast cancer incidence associated with longer use of raloxifene
...sive breast cancer for women taking raloxifene was reduced by 59% compared with women taking the placebo, and...-receptor (ER)-positive invasive breast cancer was reduced by 66%. Over the entire 8 years of MORE and CORE, the incidence of invasive breast cancer and ER-pos...MRC study reinforces effectiveness of spinal manipulation
...eatment groups reported improved back function and reduced pain over time, but to varying degrees. However, the greatest improvement was found in the patients assigned to combined manipulation and exercise. According to the ACA, the MRC study is one of a number of recent studies regarding chiropractic's ......ve been removed, the production of testosterone is reduced by half, which can affect the sexual function and well-being. The dissertation demonstrates that women who received a combination treatment of estrogen and testosterone for 6 months experienced a significant improvement in certain aspects of their s...