Reducing antiepileptics in VNS (TM) patients does not impair seizure control
...tion of specific medications affected seizure rate reductions and found that decreases in seizure frequency were relatively parallel across several medications. About Epilepsy Epilepsy is the third most common neurological disorder in the United States, affecting nearly 2.3 million people, or one percent of th...Antiretroviral therapy around childbirth reduces risk of mother-to-child HIV-1 transmission
...ild HIV-1 transmission from breastfeeding. Large reductions in transmission of HIV-1 from mother to child have been achieved in more-developed countries due to the use of antiretroviral drug therapies. Short-course regimens, suitable for resource-poor countries, have also been shown to substantially reduce HI...Community initiatives can lower adolescent pregnancy rates
... preventing teen pregnancy. The results showed reductions in birth rates in Target Area A where there was a greater concentration of community changes and a slight increase where there were fewer changes, says study author Adrienne Paine-Andrews, Ph.D., of the University of Kansas at Lawrence. Paine-Andre...First IBIS results show tamoxifen reduces breast cancer in healthy high-risk women
...ere variations, with statistically non-significant reductions in death in two trials, no difference in one trial and a statistically significant excess of deaths in the IBIS trial. Professor Cuzick said: "In IBIS there were more deaths in the tamoxifen arm with 25 against 10 in the placebo arm. Deaths from canc...Not working alone at night, outside lights can cut workplace homicides, study shows
...environmental interventions, strong and consistent reductions in the risk of a worker being killed on the job were associated with bright exterior lighting, Loomis said. Among administrative interventions, the largest beneficial effect was for staffing practices that prevented workers being alone at night. Keep...Blood pressure drugs relax heart, reduce heart failure risk
...mined again with an echocardiogram. Blood pressure reductions averaged 23 mmHg systolic and 11 mmHg diastolic after a year of treatment. Heart mass was reduced by about 10 percent on average, which led to improved blood flow into the left ventricle. At baseline, 15 percent of patients had normal left ventricu...Americans leading healthier lives, reducing risk of death from heart disease, UCSF study finds
...Department of Medicine. "We found that substantial reductions in heart disease risk factors are well worth the cost, in part because of reductions achieved by the American publics positive changes in lifestyle and habits." In fact, UCSF researcher...SNM reaction to OMB position on nuclear byproduct materials
...he NRC to evaluate its program to consider further reductions in the burden imposed by its requirements, and encouraged the NRC to undertake a full evaluation of the benefits and costs of the various requirements of Part 35, and to consider alternatives such as third-party accreditation and increased reliance o......24) were black. In addition to causing significant reductions in DNA damage to prostate cancer cells and leukocytes (white blood cells), the treatment resulted in reduced blood levels of prostate specific antigen (PSA), a protein whose increased levels are strongly linked to a higher prostate cancer risk, accor......week combination trials, statistically significant reductions in insulin resistance were only achieved with AVANDIA plus SU or MET. The results were consistent to the third study, a monotherapy trial which demonstrated a notably significant reduction in insulin resistance with AVANDIA compared with glyburide. ...... significantly fewer cardiac events, such as acute reductions in heart and respiratory rate," said pediatric neurologist Robert R. Clancy, M.D., of Childrens Hospital, the studys lead author. Allopurinol had no corresponding benefit for infants in the study with lower-risk heart conditions. All 318 infants und...... can improve asthma control and enable substantial reductions in steroid doses. The two studies are "Long Acting Beta-Agonist Monotherapy vs. Continued Therapy with Inhaled Corticosteroids in Patients with Persistent Asthma" and "Inhaled Corticosteroid Reduction and Elimination in Patients with Persistent A...UC Davis study: fewer Californians dying of lung cancer, pulmonary disease as smoking decreases
... reduced cigarette smoking. Then he compared those reductions to other states. He analyzed data for cigarette us...emature death from lung cancer and COPD because of reductions in smoking, Leistikow estimates. "We know that stopping smoking will decrease the death and widowhoo...Beyond Viagra: other phosphodiesterase inhibitors are candidates for potential therapies
...gra leads to more cGMP. In other words, PDEs cause reductions in the needed chemical in the penis, and Viagra blocks the PDE to prevent this from happening. Viagra generally does not have side effects caused by inhibition of other PDEs. "We use Viagra's mechanism of action as a beautiful example of drug and p......in the area of mental health,where there have been reductions of between 30 and 60 percent in in-patient services," he said. Like the rest of American health care, the Department of Veterans Affairs has undergone tumultuous change,Rosenheck said, especially in the move away from hospital-based care. Rosenheck ...Novartis receives FDA approval for Starlix, a new treatment for type 2 diabetes
...min was complementary and resulted in even greater reductions in HbA1c than either agent alone. Notably, within this study, Starlix demonstrated reductions in HbA1c comparable to metformin in a subgroup of 197 treatment-nave patients. In all studies, Starl...European commission grants "orphan" status for new acute myeloid leukaemia treatment
...ility of protocol assistance from the EMEA and fee reductions for all types of centralised marketing authorisation evaluation activities.If approved by the EMEA, Mylotarg would be the first product available in Europe from a new class of anticancer therapy known as "antibody-targeted chemotherapy." Mylotarg ut...Novartis receives FDA approval for LESCOL XL 80 mg
...that were 24 weeks in duration showed median LDL-C reductions ranging from 35-38 percent in patients with dyslipidemia. LESCOL XL 80 mg produced a median reduction in TG of 19 percent in patients with dyslipidemia and 25 percent in patients with primary mixed dyslipidemia (Fredrickson Type IIb). In addition, ...Increase in effective contraceptive use can reduce abortion rate
...ortion rate. The model allows them to estimate how reductions in abortion rates can be achieved by increases in contraceptive prevalence and effectiveness. According to their analysis, a woman who used no contraception would need about 12 abortions to restrict her fertility to two births. For example, in a pop......of other researchers who have reported significant reductions of lead contamination in other types of environments. Since the phaseout of leaded gasoline, lead concentrations have fallen in urban air, ocean surface water, polar ice and snow, and even human blood. But the UCSC researchers now show that contamina...