Hopkins' young researchers honored for their contributions
...ttar's research focused on understanding how light regulates the mammalian internal clock. Hattar uncovered a third class of cells in the retina that detect light, ending the monopoly of rods and cones, which for nearly 150 years were thought to be the eye's only light detecting cells. In a complex series of e...New information about heart enzymes could lead to better treatments
...ut the complex system of enzymes and hormones that regulates the cardiovascular system," Carlos Ferrario, M.D., director of the Hypertension and Vascular Disease Center and lead author of the study, reported in the on-line edition of Hypertension. "We believe this new knowledge could lead to more effective dru...Study finds nerve damage can affect opposite side of body
...Harvard Medical School. "We need to look into what regulates this communication and how it may be altered to help treat nerve injury and pain patients."...Latest cancer research features small molecule therapy, and the preventative benefits of sunshine
...udes cMyc also includes VEGF, a growth factor that regulates development of blood vessels to tumors. CX-3543 inhibits VEGF expression as well as cMyc. "We selected CX-3543 as the first 'Oncogene Inhibitor' class of small molecule compounds that specifically target the G-quadruplex regulatory elements in th...A bird 'language' gene pinpointed
... the human version of FoxP2 is a type of gene that regulates many other genes -- thus making it an ideal candidate for a gene in which a single change during evolution could create a cascade of changes that would influence an advance such as speech or birdsong. "One advantage of using vocal learning birds," s...Thyroid cancer study simplifies follow-up exams for patients
...ose of men. Located in the neck, the thyroid gland regulates metabolism through the production of thyroid hormone, which affects cell activity levels throughout the body. Treatment of a cancerous thyroid generally begins with surgical removal of the gland. To compensate, patients take thyroid medication for th...Single cocaine exposure boosts both drug craving and avoidance
...ance mechanism may be a "compensatory" effect that regulates the addictive power of psychoactive drugs. "The brain circuitry that enhances avoidance may help protect people from being overwhelmed by a single highly rewarding substance like cocaine or alcohol." Fields said. "All people are stimulated by differe...Scientists identify crucial gene for blood development
...eukemia. Called MLL, the gene makes a protein that regulates the activity of a number of other genes involved in proper development of tissues and organs during embryonic life. The experimental results being published in the March 16 issue of Developmental Cell demonstrate that MLL is necessary for the develop...American Thoracic Society Journal news tips for March 2004
... in every 2,500 white babies. A missing gene that regulates chloride and sodium transport across cell membranes causes problems, leading to dehydration and the production of very sticky secretions. In CF, the mucus-producing glands of the lung produce thick, abnormal secretions that clog the airways, damage ...Study shows 'gaming' in heart transplant system
... gaming after 1999, suggesting that the new policy regulates the system effectively, the competition driving gaming still exists. We need to remain vigilant because the continued competition for scarce transplantable organs could encourage new kinds of gaming," says the study's lead author, Dennis Scanlon, Ph....New policy stops transplant heart gaming put potential still exists
... gaming after 1999, suggesting that the new policy regulates the system competently, the competition driving gaming still exists. We need to remain vigilant because the continued competition for scarce transplantable organs could encourage new kinds of gaming." The findings are published in the paper, "Does C...New breast pap smear detects early cellular changes; May prevent onset of breast cancer
...ence of a specific gene called RAR beta. This gene regulates how breast cells use vitamin A in order to maintain their proper health. Studies have shown that RAR beta loses its ability to function in many women with breast cancer. If RAR beta is present inside cells, vitamin A can do its job: regulating how br...How the cellular 'garbage disposal' grinds to a halt to cause Batten disease
...hat the genetic defect is linked to a protein that regulates the amino acid arginine in and out of a yeast organelle called the vacuole. The vacuole in yeast is much like the lysosome in human cells, slicing and dicing up cellular waste and then disposing or recycling the material. In Batten disease and other ...UCSD researchers describe cell activity leading to disruption of neuron migration
...oted. "With the discovery of Cdk5 as a factor that regulates doublecortin, we are learning more about this vital developmental process. Eventually, discoveries such as this will contribute to therapies to prevent abnormal brain development." In back-to-back published articles in 1998, Gleeson and a team led ...Emotion-regulating protein lacking in panic disorder
... key component of a chemical messenger system that regulates emotion, researchers at the NIH's National Institu...iety. Stimulation of 5-HT1A receptors in the raphe regulates serotonin synthesis and release. In an earlier PET study of depressed patients, using a different tr......telling the brain and body what to do." This area regulates impulse control, attention, movement and elaborating on thoughts. The study used a variation of magnetic resonate imaging (MRI) technology to measure the level of six metabolites (any substance produced by metabolism) in a small portion of the fronta......ay initiated by adhesion in human neutrophils that regulates the generation of ROS, and thus inflammation. This data is of broad significance to our understanding of the innate immune response and its normal regulation. TITLE: The molecular basis for adhesion-mediated suppression of reactive oxygen species ...Investigational drug brings new hope to kidney cancer patients
...d to inhibit an enzyme, known as Raf kinase, which regulates tumor-cell proliferation and may also play a role in the growth of new blood vessels to feed the tumor....Key feature of HeartMate II heart assist device developed at University of Pittsburgh
...at feeds blood to the entire body. A system driver regulates pump speed. When implanted, HeartMate II takes over most of the function of the left ventricle, the heart's main pumping chamber, and helps generate the force necessary to propel oxygen-rich blood throughout the body. Without such circulatory support...Experimental drugs reduce neuron death in rats following insulin shock
...f insulin, a hormone produced in the pancreas that regulates glucose (sugar) levels in the blood. Diabetes patients monitor their blood sugar, often several times a day, and inject themselves with insulin to maintain appropriate blood sugar levels. However, calculating the correct dose of insulin can be diffic...