Tag: "rejection" at medical news
Intestine Transplant Results Reported At American Society Of Transplantation Meeting
...e-yearsurvival, including: improved management of rejection
with a three-drugcocktail of tacrolimus, steroids and daclizumab; refined donor and recipientselection criteria; and modification of the surgical procedure, including donorbone marrow augmentation. Twenty-seven of the patients received donor bonemar...
New Procedure Makes A Successful Transplant Possible
... PRA presents a different,much more potent risk of rejection
than cell-mediated rejection, which alltransplant patients face. "High PRA can cause immediate rejection
of a transplanted kidney, in spite ofthe powerful anti-rejection medications we have available," say...
Medical tip sheet for June 4 (a)
... approach that appears to significantly reduce the rejection
riskof transplanted organs is currently being studied in multi-center clinicaltrials but already has been adopted as an effective tool by most majortransplant centers throughout the country. The therapy was developed atCedars-Sinai Medical Center in ...
Double transplant frees patient from need for immunosuppressive drugs
...or and recipient are blended in away that prevents rejection
of the transplanted kidney by the recipient's bodyand suppresses an attack of the donor's immune cells on the recipient's organs,a dangerous condition called graft-versus-host disease. While the strategy wasused in this patient to treat both kidney ...
Brain chemical mellows male mice, but makes mouse moms tough
...ntlessly attacking other males and ignoring female rejection
of attempts tomate. The latest research sought to expand that finding by determining theeffect of a lack of nitric oxide on females' aggressiveness. "Male mice are aggressive in a variety of contexts, but the female mousenormally only attacks other m...
Researchers complete sequence and gene map of human major histocompatibility complex
...of the immune cells, including the transplantation rejection
process and the killing of virus-infected cells by specific killer T lymphocytes. This region harbors several disease associations and the variability in this region between donor and recipient is a critical factor in marrow transplant matching. ...
Recipients of well-matched kidneys received locally require less long-term care
... tissues, called HLA markers, had little effect on rejection
of transplanted kidneys. In contrast, a new study of 27,050 kidney transplants demonstrated a significant increase in the need for care within three years of transplantation as the number of mismatched tissues increased. "Although the transplanted k...
Making kidney transplants last longer: Large UM study finds newer drug is better
... was not just due to MMF's ability to reduce acute rejection
responses. In fact, the new results show the relat...of avoiding acute rejection, the threat of chronic rejection
and loss of the kidney within a few years still looms," says Kaplan. "Our results suggest that thera...
Humans can regrow liver from bone marrow
...-cell transplant, solving both organ shortages and rejection
issues. "When we identify what the stem cells look like, we could extract some from a patient's blood, grow them in culture, and then reinject them," he said. Because the liver also performs complex reactions such as protein manufacture and chemica...
Post-traumatic stress disorder found in mothers whose children receive a bone marrow transplant
... overwhelming for some mothers. The rate of graft rejection
and possible death can be as high as 50 percent for some patients. Bone marrow transplants can also create opportunities for serious infections and recurrence of the malignancy is a possibility. "Regardless of the advancements in this area of t...
New procedure makes kidney transplant an option for thousands on waiting list
...h transplants, greatly reduces the chance of organ rejection
in patients with elevated antibody levels. Previously, these elevated antibody levels made tissue rejection
almost certain. Mayo Clinic is one of three medical centers in the United States that offer this pr...
Newer form of 'gold standard' drug helps kidney transplant patients do better in long term
...the "gold standard" drug against kidney transplant rejection
not only costs less and gets absorbed better - it also helps transplant recipients keep their new organs longer. That's the finding of a new University of Michigan Health System study that answers a question pondered by transplant physicians and tens...
Baylor team discovers reason for heart transplant failure
...hs and even years after surgery, including cardiac rejection
and the development of transplant coronary artery ...splant, Bowles said. The infections or evidence of rejection
did not show up on non-invasive tests. The findings indicate that the current therapy for transplant...
Atlantic Ocean no barrier to transplant pathologists in Pittsburgh and Sicily doing routine consults through unique telepathology system
...perating room table. In addition, diagnosing organ rejection
can be tricky, as there can be nuances in how rejection
can manifest itself. The pathologist's report determines in large part if and how rejection
is to be...
Researchers identify a key 'brake' of the immune response
...The results show that the heart recipients without rejection
had T-suppressor cells that had been primed to suppress a response to foreign hearts. The findings of the study also have implications for type I diabetes and other autoimmune diseases, Dr. Suciu-Foca says. In autoimmune disease, the immune system at...
Duke researchers identify the mechanisms by which drug combinations kill fungal infections
...orin or FK506, two drugs commonly used to suppress rejection
of transplanted organs and tissues. The study...logy Organization. Cyclosporin and FK506 block rejection
of transplanted organs by inhibiting immune-system signaling pathways that activate T-cells. These d...
JDRF launches multimillion-dollar Center for Islet Transplantation at Emory University
...s an important issue facing islet transplantation: rejection
of donor islets by the patients immune system. Alt...with groundbreaking research on strategies to stop rejection
of transplants by establishing true immune tolerance, is a central focus of the Emory Transplant Cen...
University of Pittsburgh transplant researchers present findings at international meeting
...lant teams is the fact that drugs to prevent organ rejection
suppress the patients' immune systems, making thes... better identifies transplant patients at risk for rejection
A simple blood test takes much of the guesswork out of predicting who is at risk for severe organ ...
Why heart transplant patients resume smoking revealed in University of Pittsburgh study
...ugs that transplant patients take to prevent organ rejection
suppress their immune systems, making these patients more susceptible to infections and cancers. A smoking history and relapse to smoking could very well compound cancer risks for transplant patients. Indeed, in recent years, transplant teams have se...
Test identifies patients at risk for severe organ rejection, say Univ. of Pittsburgh researchers
...on may help clinicians tailor therapies to prevent rejection
from actually occurring. Indeed, in a retrospecti...of these 10 (50 percent) actually developed severe rejection
within a month, compared to three of the 26 (12 percent) negative-ELISA patients who developed rejec...
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