Stanford team prevents kidney transplant rejection without drugs
...n the journal Transplantation May 15. Organ rejection after transplantation occurs because the immune sy...pressing drugs, which were needed to prevent organ rejection while the team completed the next step. After the transplant, the kidney recipient received ......e waiting lists and solve the big problem of organ rejection by growing them from the patient'scells. Tissue engineers can already grow simple body tissues such as knee cartilage. They start with a shaped, porous scaffold made from a biodegradable plastic like polylactic glycolic acid (PLGA). The scaffold is ...Stanford researcher dusts off old drug; uncovers new anti-rejection properties
...- would become popular in 1999 as a way to prevent rejection of transplanted organs. Now, new studies fr...ican Transplant Congress. Acute transplant rejection occurs when cells of the immune system recognize the transplanted organ as foreign and attack it as ...Drug reduces risk of acute rejection in kidney transplantation
...has found that a drug normally used to treat acute rejection of transplanted kidneys also can dramatically prevent rejection when administered during surgery. These findings are important because avoiding acute rejection hel...Hope for kidney transplant patients of improved graft survival
...imen with low toxicity, Zenapax prevents the acute rejection of the newly transplanted organ, and Cymevene/Cytovene/Valcyte has been developed for the prevention and treatment of cytomegalovirus, a dangerous viral infection associated with transplantation. Recently, Roche have announced a co-development agreem...Matching for liver transplants could prevent disease recurrence, says Pitt study
...cipient not only has an impact on the incidence of rejection and graft failure, but disease recurrence after tr... match between donor and recipient indicates organ rejection is less likely, a match also increases the odds that patients transplanted for hepatitis C or primar...Pitt study: Chronic rejection rare for pediatric liver transplant patients on tacrolimus
...ncompliant with taking his medication, the chronic rejection was resolved in the three children once normal tac...ed Dr. Jain. There was a total absence of chronic rejection in the pediatric population who were maintained on tacrolimus. Inability to maintain baseline immuno...Heartburn surgery helps lung transplant patients
... positive effect on an untreatable form of chronic rejection in lung transplant recipients. The procedure, known as fundoplication, creates a super-competent sphincter at the point where the esophagus meets the stomach. Surgeons create this sphincter by wrapping the top portion of the stomach around the base ...American Thoracic Society Journal news tips for May (second issue)
...ansplant physicians couldbegin treatment while the rejection process was still T cell dependent, before the development ofwidespread and fixed airway injury. (OB is a syndrome of often severe fiber proliferatinginjuries in airways and small pulmonary blood vessels that eventually affects one-half or more oflon...Homeless sexual minorities at greater risk for physical and sexual violence, mental illness
...ecause this population has been exposed to so much rejection based on their sexual identity. The study was multi-ethnic, with 53 percent of the subjects identifying themselves as white, 19 percent as American Indian or Alaskan native, 18 percent as black, 7 percent as Hispanic and 3 percent as Asian or Pacifi...New approach to post-transplant lymphoma shows promise
... reducing the doses of the drugs that suppress the rejection of the transplanted organ and the function of the ...e therapy has some limitations, noting that kidney rejection did occur in those patients with PTLD in the transplanted organ. Still, the survival results from ...Muscle stem cells show promise against muscular dystrophy in mouse model
...ed to regenerate muscle tissue; and 4) they resist rejection by a foreign immune system. When these cells w...l survival rate, poor spreading of cells, and cell rejection by the immune system are being overcome. This, say the scientists, could make treatments for MD...Post-transplant nerve regrowth better with young hearts, quick surgery
...(11 of them women) who were not experiencing organ rejection or other severe problems were examined with positr...plant recipients who are younger or those with few rejection episodes can expect a higher likelihood of reinnervation and thus higher likelihood for improved exe...Hormone prompts adult stem cells to differentiate into islet cells
...grown from a patient?s own stem cells, the risk of rejection is gone," says Habener. "And now with the addition of GLP-1, we might be able to stimulate those cells to become truly functional." Habener stresses that the NIPs are derived from adult tissues. Therefore, the ethical issues that surround fetal or...Too many lungs rejected for transplantation, study shows
...urnal Lancet, concluded that existing criteria for rejection may be too rigid. Researchers used physiological, microbiological and other methods to assess 29 pairs of rejected lungs and found that 40 percent of the rejected lungs might have been candidates for transplantation -- more than doubling the number o...Are too many lungs not being considered for transplantation? (p 621)
...e being rejected because the existing criteria for rejection are too rigid. The investigators obtained 29 pairs of rejected lungs and assessed them by physiological, microbiological, and histological methods. When all factors were considered, including microbiological and non-lung donor factors, approximately ...Novel kidney transplant technique prevents rejection of donated organs
... average of 13 months post-transplant. Most organ rejection occurs during the first three months following surgery. "I've been in this business 30 years and I've never seen anything like these results," says Andrea A. Zachary, Ph.D., lead author of the antibody study and associate professor of medicine at ...Combined kidney and bone marrow transplantation allows patients to discontinue anti-rejection drugs
...tient remains in remission from cancer and free of rejection of the transplanted kidney. The second patient was transplanted in August 2000 and also remains in remission and rejection-free. The additional patients described by Sykes are the first treated under a multi-institutional study sponsored by the Imm...Strategies allow for drug-free transplants, report researchers at international congress
...some patients the researchers had to back off when rejection occurred, they do plan to continue weaning the pat...r one year. The Pittsburgh team's encounters with rejection and the results of a third study from Stanford University are a reminder of the formidable challenge...More hand transplants to be performed, predict experts at international congress
... Italy, France and the United States reported that rejection can be controlled effectively with the mainstay of...e the required drugs to control rejection. Indeed, rejection resulted, manifested by painful lesions on his arm and hand. Studying the amputated graft indicated ...