Tag: "releasing" at medical news

NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System

..., the kidney attempts to counterbalance thedrop by releasing the enzyme, renin. Renin in turn catalyzes the production ofangiotensin, a hormone circulating in the blood. The ACE enzyme converts theinactive form of angiotensin-'antiotensin I' to angiotensin II, which is apowerful vasopressor (constricter of blo...

Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis

...ncounter freely diffusing an active nerve terminal releasing the appropriate neurotransmitter, namely glycine, they open and the resulting ion flux generates a local change in membrane potential. This induces the opening of voltage-gated calcium channels. The resulting ca...

Research Explains Lithium's Dual Anti-Manic/Anti-Depressive Effect

...n across the synapse. Astructure on the end of the releasing nerve cell, called a reuptake transporter,then shuts off the signal by reabsorbing the glutamate, pumping it back into thecell for reuse. If the reuptake mechanism malfunctions, inappropriate concentrations ofneurotransmitter remain in the synapse. ...

MIT Microchip Releases Chemicals On Demand

...rvoir, andthe thin gold cap covering it dissolves, releasing the chemical inside. "The Nature paper shows that this basic concept works," said Dr. Cima,Sumitomo Electric Industries Professor of Ceramic Processing. "The next step isto do the engineering to make this into a real application." The dime-s...

Neutron Research To Help In Treatment Of Cancer Patients

...tope. The neutronscause the boron nuclei to split, releasing alpha particles that damagesurrounding cells. The path length of alpha particles is the diameter of a fewcells, much shorter than the path length of electrons. "Gamma rays often wanderaround in the healthy tissue," Grimes says. "Neutrons don't go ver...

Stress Hormone Tied To Depression And Conduct Disorder In Pregnant Teens

... the first interview and the hormone,corticotropin releasing hormone (CRH), was measured. The researchers found that lower CRH concentrations in the blood earlyin pregnancy were associated with a greater number of conduct disorder symptomsduring early, but not late, pregnancy and predictive of the same...

Randomized Contolled Study Shows Neostigmine Is An Effective Treatment For Acute Colonic Pseudo-Obstruction

...gland Journal of Medicine. However, the journal is releasing the study sevenweeks early on its Web site, http://www.nejm.org , to ensure that doctors whotreat the condition are notified as quickly as possible. The article is entitled"Neostigmine for the Treatment of Acute Colonic Pseudo-Obstruction." ...

Scientist explain a drug's paradoxical action: discovery may lead to new therapies for breast cancer, early puberty

... of a chemical signal called GnRH, forgonadotropin releasing hormone. GnRH instructs the ovaries and testes to startmaking steroids, including sex hormones. For children who start to develop sexcharacteristics very early - as young as toddler age - Provera is one of anumber of drugs that can be used to delay t...

Allergy-producing cells are also 'do-gooders,' helping stave off infections

...n triggers mastcells to alert the immune system by releasing a substance called tumor necrosisfactor alpha (TNF...ecognizing bacteria and stopped the mast cellsfrom releasing the signaling molecule TNF-a in the presence of bacteria. Thisfinding led the researchers to conclud...

Alcohol: the chemistry of the dark side

... release of stress chemicals,such as corticotropin releasing factor (CRF), that create tension anddepression. In combination, the depletion of pleasure chemicals and thestimulation of stress chemicals creates a persisting chemical imbalance thatleaves the alcoholic vulnerable to relapse, he said. Hoping...

Study reveals how brain controls eating in normal rats

...ans to eat. Leptin prevents orexigenic cells from releasing a potent appetite-stimulating neuropeptide. The net effect is that the leptin-sensitive cells send appetite-suppressing signals to key nerve cells in the lateral hypothalamus thought to control several behaviors including feeding, including a group...

Inflammatory pain may help deter inflammatory diseases like arthritis

... the neutrophil, which sweepsinto an injured site, releasing chemicals that work to heal wounds. "Our work suggests that pain acts as a negative feedback control ofinflammation," said the lead author of the study, Holly Strausbaugh, PhD, apostdoctoral fellow in the NIH Pain Center at UCSF. "Once enough inflam...

First brain cancer surgeries using new space-age probe are successful

...head-size Light Emitting Diodes (LEDs) -- a source releasing longwavelengths of light -- to activate light-sensitive, tumor-treating drugs. To ensure other promising LED medical applications are investigated,NASA recently selected a Phase II Small Business Innovation Research proposalfor negotiation wi...

It's high time we registered all clinical trials say editors of Lancet and BMJ

...is be, ask the authors, when all they are doing is releasing administrative information and not actual data? Horton and Smith conclude that the pressure to register trials will only come when research ethics committees, medical research charities and drug and device manufacturers start to encourage trialists t...

Nausea from anesthesia plummets with extra oxygen

...re known to react to an inadequate oxygensupply by releasing neurotransmitters and other potent chemical messengers thatin turn cause nausea and vomiting. This is thought to be a reaction evolved torid the body of possibly life-threatening, noxious food. In other words, many surgical patients have an unconscio...

Oregon Health Sciences University Researchers track long-term results of chemotherapy assisted by blood-brain barrier disruption

...rs of additional research, OHSU scientists now are releasing the encouraging results of a long-term study involving patients who have beaten the odds thanks to chemotherapy assisted by blood-brain barrier disruption. The results of the study are published in the January edition of the journal Neurosurgery. OHS...

Scientists develop transgenic mouse that models Parkinson's, related disorders

...that regulate the activity of other brain cells by releasing a chemical called dopamine. "Previous models for Parkinson's disease in mice have been achieved through chemical or surgical techniques that interfere with the dopaminergic system, but it is unclear whether these interventions simulate what triggers...

Purdue 'stealth compounds' attack cancer cells

...he compound enters a cell, enzymes break it apart, releasing the nucleotides into the cell. Because the enzymes needed to break the compound apart are found only in cancer cells, the new method may allow researchers to develop drug therapies with fewer side effects, Borch says. "Though a stealth compound i...

Scientists develop polymers with nitric-oxide releasing particles

...generating polymers. U-M research to develop NO- releasing polymers is funded by the National Institutes of Health and Michigan Critical Care Consultants, Inc. of Ann Arbor, Mich. Kelly A. Mowery and Jeffrey K. Politis, former U-M graduate students, and Melissa Batchelor and Bong Oh, current U-M graduate st...

Chemist uses DNA to trigger an alternative chemotherapy method

...rug component and a catalytic component capable of releasing the drug from the prodrug. A prodrug is an inactive form of a drug that has no therapeutic value until it is converted into the active form of a drug. To make the prodrug component, Zaochun Ma, Ph.D., Taylor's post-doctoral researcher at Washington...

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