OneWorld Health licenses compounds from Yale, U of Washington to treat major parasitic diseases
...ecting a lead candidate among the compounds, which represent the first new potential drugs to treat Chagas disease in decades. The compounds were developed by teams led by Andrew Hamilton, deputy provost for science and technology at Yale and professor of chemistry, in collaboration with Frederick Buckner, Mic...Smoke-free rules may be good news for business
... 1995. They evaluated data from jurisdictions that represent 63 percent of the state's population: Erie, Monroe, Suffolk and Westchester counties and New York City's five boroughs, which the researchers treated as a single jurisdiction. The most positive finding, for restaurateurs, the state and taxpayers: Th...Physicians not 'easy marks' for drug sales reps, argues O.R. study
...$.5 billion to over $1 billion. In total, the data represent over 4 million interactions between physicians and pharmaceutical sales representatives. For each of the drugs in the study the authors used statistical modeling and operations research methods to assess the effect that changes in the amount of deta...MRI may help find missed breast cancers in high risk women
...mal examinations that were eventually shown not to represent cancer (false-positives). Further studies such as a repeat MRI at six months or a biopsy were recommended after 35 (36. 5 percent) of the 97 screening examinations and after 11 (39.3 percent) of the 28 short-term follow-up examinations. Altogether, b...Increased heart mortality rates linked to lower state subsidies of uninsured in New Jersey
...pital reimbursement that we observed in this study represent only one segment of the patient population in one state, but may be an indication that we need to pay close attention to how cost-saving reforms may affect the quality of care across the country," Volpp said. The research is published in the April i...Alcohol makes auto crash injuries worse for drivers and passengers, study finds
...d the U-M Transportation Research Institute. They represent the most in-depth clinical study to date demonstrating the connection between alcohol use and injury severity: Earlier population and animal studies have suggested the effect, but it has never been thoroughly examined in a clinical setting. Among oth...Outpatient setting very safe for skin cancer surgery
...rming Mohs surgery on an outpatient basis does not represent an undue risk. Mohs surgery, also known as microscopically controlled surgery, was developed by Frederic Mohs, M.D. for the treatment of certain skin cancers. Performed under local anesthesia, the technique combines surgical removal of the skin cance...Domestic violence levels high in rural Uganda
...rtant indirect evidence that domestic violence may represent a significant factor in increasing women's vulnerability to HIV acquisition in settings such as Uganda," explained Dr. Koenig. "Fear of HIV infection may lead women to avoid sex with their partner, which in turn may precipitate threats of violence or...New study finds women in Philadelphia region still face significant inequality at work and at home
...ort and administrative support. These occupations represent the lowest paying jobs in the workforce with median hourly wages ranging from $7.40 to $10.18. Dana L. Barron, associate director of the University of Pennsylvania's Alice Paul Center for Research on Women and Gender , in collaboration with Laryssa M...Heart devices, transplants have similar costs; what will we pay?
...ospital ranged from 16 to 55 days. These patients represent the type of person most likely to receive an LVAD in the future, say the researchers. Several factors predicted how long patients would stay in the hospital. For example, patients who developed general or device-related infections tended to have lo...American Thoracic Society Journal news tips for November (second issue)
..., neural deficits have been justifiably assumed to represent a consequence of sleep-disordered breathing rather than to precede the syndrome. "Perhaps the time has come to reverse our thinking," he said. The research and editorial appear in the second issue for November 2002 of the American Journal of Respir...Northwestern receives $5 million to study polycystic ovary syndrome
...dy hair and increased risk for diabetes. The SCORs represent an important new NIH initiative in women's health. Northwestern was one of 11 leading medical institutions selected as SCOR sites on the basis of having at least three highly meritorious research projects that explore an important issue related to s...Assoc. of American Medical Colleges honors University of Washington medical school
...rries out a broad range of programs and studies to represent its constituents. The Association works to strengthen the quality of medical education and training, to enhance the search for biomedical knowledge, to advance research in health sciences, and to integrate education into the provision of effective he...Schizophrenia drugs linked to increased risk of heart attack
... that with haloperidol. Thioridazine may, however, represent an elevated risk at high doses," said Sean Hennessy, PharmD, PhD, assistant professor in Penn's Department of Biostatistics and Epidemiology. "To reduce cardiac risk, thioridazine should be prescribed at the lowest dose needed to obtain an optimal th...JCI table of contents, November 4, 2002
...erminal centers, suggesting that FDC disruptionmay represent a candidate for the transient alteration of human immunefunction during disease. CONTACT: Jeffrey L. Browning Biogen Incorporated 12 Cambridge Center Cambridge, MA 02142 USA Phone 1: 617-679-3312 Fax 1: 617-679-2304 E-mail: jeff_browning@biogen.com ...Scripps Research Institute group designs DNA vaccine that inhibits growth of cancerous tumors
...ial cells are not prone to mutations and therefore represent a more stationary target. And targeting the endothelial cells proved effective because these cells are absolutely necessary for tumor growth, since they provide the blood that the tumor cells need to grow. The DNA vaccine uses an antigen "marker" kn...Guidelines issued for metabolic complications related to HIV & antiretrovirals
...and may change as new data become available. They represent what is reasonable to do in a clinical practice based on the currently available evidence," said Schambelan. Estimated percentages of patients experiencing each complication and possible causes are also discussed in the article. "We are not completel...University of Pittsburgh researchers link gene to depressive disorders in women
...ers such as major depression, which is unlikely to represent a single disease with a unitary cause," said Dr. Zubenko. "Instead, clinical depression is probably more like anemia. Both of these disorders are defined by a collection of clinical features that result from different causes in different people. Trea...Distortion and lack of openness - Information provision from the pharmaceutical industry
...ce. Sometimes, their commercially determined goals represent genuine advances in health-care provision, but most often they are implicated in excessive and costly production of information that is largely kept secret, often duplicated, and can risk undermining the best interests of patients and society." Ike I......tional subdivisions," says Van Essen. "Our atlases represent the most accurate and comprehensive maps of cerebral and cerebellar cortex available for humans, macaque monkeys and mice." Macaque monkeys are the most intensively studied nonhuman primate, and mice are the most intensively studied rodent. Detailed...