New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
... of theAmerican Society of Clinical Oncology. UCSF researchers found that the osteoporosis prevention drug, raloxifene,drastically reduced the risk of breast cancer in postmenopausal women withoutindicating an increased risk of endometrial, or uterine cancer. Other drugs inraloxifene's class, including tamoxife...Metrifonate, A New Alzheimer Drug, Helps Behavior Problems
...t know which typeof pill they were taking, and the researchers didn't know who was in whichgroup. Test scores during treatment were compared with those at the beginningof the study. One test, involving paper and pencil tasks, evaluated cognitiveperformance. Through interviews with subjects and caregivers......theincidence of post-angina heart-attacks that the researchers recommended its useas part of a new therapeutic standard of care. The researchers' study andclinical recommendation will be published in the May 21 issue of The New EnglandJournal of Medicine. Unstable angina is a life-threatening cardiac co...Drug's Effect On Chromosomes May Explain Second Cancers
... into a DNA damaging agent,” saidMuller. The researchers studied etoposide and five other topo II inhibitors onfragments of DNA that contained telomeres. Based on a knowledge of how the drugs interact with DNA, the researcherspredicted that most topo-II inhibitors should cause breaks in telomeres.To test ...New Treatment Targets Most Malignant Brain Tumors
...e cancer, called glioblastomamultiforme (GBM), the researchers believe it will constitute a powerful newweapon to... beam radiation therapyfor the tumors. The researchers also have begun initial tests using another radioactiveisotope, Astatine-211, that has been a far mo...New Radiation Procedure Targets Liver Malignancies
...r on the U-M liver cancer study. For 10 years, U-M researchers William Ensminger , M.D., Ph.D., Theodore Lawrence, M.D., Ph.D., and Randall Ten Haken, Ph.D., have investigated the use of focal liver irradiation along with chemotherapy delivered directly to the tumor via the hepatic artery. As a result of that ...Dying To Quit: Why We Smoke And How We Stop
...ological and scientific factors that she and other researchers have been studying and that are largely unknown to the general public. The ways that nicotine affects the body and brain, the emotional comfort and the pleasure of the smoking ritual, the impact of marketing--Brigham shows how all are inseparable par......edication,according to the study. National Jewish researchers followed 24, 6-12 year olds with asthma for threemonths. During that time, parents monitored their child's medication use with ahand-written diary. In addition, a small computer, which records the date andtime the drug is taken, was embedded into a...Unhealthy Lifestyles Not Primary Cause Of High Mortality Rates
...ts who were first interviewed in 1986. The researchers found that those with low levels of income and education were significantly more likely both to engage in risky health behaviors and to die. For example, compared with people with annual family incomes over $30,000, those with incomes of less than $......e dysfunction forabout 4 years and 10 months. The researchers took data from three European,double-blind, placeb... versus-4% to 7% for patients taking placebo. The researchers concluded that oralsildenafil resulted in "significant improvements" in key Quality of LifeParameter......g of ginkgo biloba extract per day orplacebo. The researchers examined 23 patients after a 24-week treatment cycle. Nine patients had dropped from the study. They said: "In contrast to anuncontrolled pilot study, a placebo-controlled, double blind evaluation couldnot prove any benefit from treatment with oral...Athletes, Fraternity Men Are Top Drinkers
...ully as they do their teams' win-loss records, the researchers say. "Maybe the pressures on athletes are greater than anybody realized," says Leichliter. "We need to do a better job of helping them manage the demands they face."...ACE-Inhibitors Score High In Reducing Heart Attack Deaths
...rson's odds of surviving after a heart attack, say researchers reporting on astudy of nearly 100,000 heart attack...he drug group versus 0.6 percent in controls. The researchers lackdata on whether those conditions improved when treatment was stopped. Those twocomplications wer...Pioneer In Nuclear Medicine Wins Lifetime Award
...se in his work. (Carbon 14's long half lifeallowed researchers to study single cells in test tubes, thereby revolutionizingbiochemistry; but Wagner needed more high-energy isotopes.) He led a resurgenceof interest in the shorter-lived isotopes produced by cyclotrons, which, unlikeCarbon 14, had the high energy n...More Bad News For Fast Food Fans
...and increase the risk of heartdisease according to researchers at the San Francisco Veterans Affairs MedicalCente... the negative effects of oxidizedcholesterol. The researchers studied two groups of genetically similar rabbits. Both groups were fed a low cholesterol diet but ...Fast Food Can Speed Up Clogging Of The Arteries
...quantity of oxidized cholesterol in the diet. The researchers found that inrabbits, the dietary oxidized cholesterol accelerated the process ofatherosclerosis, or clogging of the blood vessels. It is thought that blood vessels can oxidize cholesterol, leading to acollection of fat called plaque. But th...Abstinence Reduces HIV For High-Risk Women - Even Those Who Relapse - Study Shows
...ong a targeted group ofintravenous drug users. The researchers modeled a group of 10,000 intravenousdrug using women over a two-year period. If there are 25% relapses to riskybehavior during the period, there would be prevention of 1 infection in infants,72 infections in adults, and $16 million in savings. If re...Crystal Structure Of gp120 Reveals HIV In Action
...of gp120 in action is a collaborativeeffort led by researchers from the Columbia University College of Physicians...ble sequences. So to coax gp120 tocrystallize, the researchers snipped off parts of it, using genetic clues fromthe virology team at Dana-Farber. "From years of wo...UCSF Study Finds Popular Blood Thinner Does Not Weaken Bones
...n R. Cummings, MD, UCSF professorof medicine. UCSF researchers were concerned that warfarin increased the risk of osteoporosisin older women because it suppresses vitamin K, which may be necessary forbuilding bone, Jamal said. Osteoporosis is a common condition among older womenand warfarin, which is widely used...... first and sixth weeks of irradiation. The researchers found the combined treatment was more successful incontrolling the cancer and in stopping recurrence of tumors. Sixty-one percentof the combined treatment patients were still disease-free after three years,compared to 41 percent for the intensive rad...