AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...hiding, and to understandwhy it eventually becomes resistant to drug therapy." HIV is found in three "compartments" in the body, Bartlett said.The largest is the lymphoid tissue, such as nodes, liver and spleen. Theothers are plasma and peripheral blood cells. While clinical trials are under...Scientists Produce New Anti-Malarial Compound
...ause Plasmodiumparasites are becoming increasingly resistant to chloroquine andother traditional drugs used to treat malaria patients. The anti-malarial drug artemisinin, extracted from the plant Artemisiaannua, has been successful in curing malaria patients in China.But plants contain only small amounts of th...Study Shows Major Savings In Supervising TB Care
...oner and decreases the risk of developing TB germs resistant to treatment, says Richard E. Chaisson, M.D., associate professor of medicine. The researchers found that using DOT throughout the United States would save $25 million compared with conventional therapy, save 240 additional lives, and prevent 2,400 r...New Approach To Multidrug Resistance
...ssof chemotherapy in cancer cells that have become resistant to its effects. Thetechnique temporarily inhibits production of a prime protective mechanism usedby tumors -- a molecular pump called P-glycoprotein that flushes drugs out ofcells. The study, conducted by Associate Professor of Pharmacology andToxico...MIT Solution To Math Problem Could Lead To Better Dental Implants, More Resistance To Missiles
...mplants that won'tcrack and tank armor that's more resistant to missiles. It could also radicallychange the way... properly constructed graded material will be more resistant tocracking and wear. That could have implications for, among other things, the materials us...Penn Researchers Create Drug To Help Target Attack On Cancerous Tumors
...rive in oxygen-starved environments--are much more resistant to radiation and chemotherapy than their non-hypoxic cousins. But until now, physicians have had difficulty assessing hypoxicity "When we know which tumors are hypoxic, we'll be able to custom-tailor a patient's cancer treatment,...Tighter Chemical Binding = Better Meds
...anti-HIV drugs that counter mutant strainsthat are resistant to current drugs, such as AZT and the proteaseinhibitors. Jorgensen's calculations also have been applied to potentialdrugs that can regulate the natural synthesis of insulin for diabetics ina gene therapy approach involving implanted cells. Vast I...UF Psychiatrists Use Antidepressants To Treat Smoking Addiction
...ddictive," and nicotine dependence is particularly resistant to treatment, he said. Treatment programs for alcoholism and cocaine addiction are effective at least half the time. In contrast, although 80 percent of smokers want to stop, only 20 to 30 percent of those who do are smoke-free a year later....Emerging Pathogens And Safety Of Fresh Produce Key Issues Facing Food IndustryAnd Scientists
...y life-threatening. Salmonella typhimurium DT 104, resistant to most commonly prescribedantibiotics, will speci...ored will be the potential for pathogens to become resistant to sanitizingagents and antimicrobials added directly to foods or packaging as well as thebiological......f prostate cancerfor some patients who have become resistant to standard hormone treatment.The finding was pres...ndvirtually all deaths result when patients become resistant to this treatment. Few therapeutic options exist, either for treating the disease or forcontrolling ...Synthetic Detergent Found To Fight Multi-Drug Resistance
...he cell membranes of certain cancer cells that are resistant to awide variety of anti-cancer drugs. Tumors that contain a high content ofP-glycoprotein fail to respond to chemotherapy because the pump rapidly removesthese drugs from cells, preventing their killing action. The pump is also foundnormally in the ...International Panel Evaluates Testing For Drug Resistance In HIV
... in guiding treatment, particularly in areas where resistant strains areprevalent." The panel was made up of 1...ication will probably lead to the proliferation of resistant strains. Therefore all patients should receive potent combination drug therapy regimensthat have the...New Guidelines Stress Early Potent Drug Cocktails, Individualized Therapy
...blood will allow physicians to detect and react to resistant virusstrains and treatment failures. Despite concern for the emerging side effects of long-term treatment, therapiesshould be continued to fight HIV effectively, the panel recommends in itsreport, published in the July 1 issue of the Journal of the A...Many Gay Men Infected With HIV Are Opting To Delay Treatment, Despite Availability Of Drugs
...thanfollowing it inconsistently, possibly creating resistant strains. From anadherence standpoint, it is probably better if someone who's not sure waits tobegin therapy." The study, led by UCSF associate professor of medicine Joseph Catania, PhD, isthe first random household-based probability sample of gay me...Only Eight Percent Of San Francisco HIV-Positive Urban Poor Receive Protease Inhibitors
...esponse to concerns that the urban poor maydevelop resistant strains of HIV as a result of not adhering to their therapy. The UCSF team looked at how many of these people who were HIV-infected receivedtherapy, how well they adhered to their regimens, and how the virus responded.David Bangsberg, MD, MPH, assist......s more likely than white teen-agers tohave steroid resistant asthma, research at National Jewish Medical and ResearchCenter has found. "Our results suggest that children with steroid-resistant asthma are more likelyto be African-American, to have required treatment with oral steroids at anearlier age and to re...UCSF AIDS Expert Warns Against Early Treatment For HIV Infection
...mmune cells can control the virus and selection of resistant mutants can beavoided. In presenting his case, Lev... the drugs themselves thatencourage these types of resistant viruses. Any replication of HIV will lead to irreversible destruction of the immunesystem. -- What ...UNC Researchers Find Drug-Resistant HIV In Semen
...that sexual fluidsor genital secretions do contain resistant virus, so the fear that there is somespread of resistant HIV is founded on logical scientific evidence," he says. The mutated HIV strains inc......de quite a bit of information and others are quite resistant to it,seeing it as a step backwards scientifically. While there is room for bothviews within the college, I hope this study gives people a little moresense of permission to teach these things. Teaching about them does nothave to be an endorsement." ......tiviral agents, such asamantadine and rimantadine, resistant virus emerges readily; however, resistancehas not been detected in the treatment studies with zanamivir. Zanamivir is thefirst orally inhaled drug in a new generation of specific treatments against theinfluenza virus known as neuraminidase inhibitor...