Tag: "restenosis" at medical news

Study finds drug eluting stents as effective as vascular brachytherapy in preventing restenosis

... create new blockages -- a process called in-stent restenosis (ISR). At present, vascular brachytherapy (cathete...to radiation and is associated with a risk of late restenosis (20 to 40 percent) and late thrombosis. However, whether SES is superior to VB long-term remains an ...

Three anti-platelet drugs used in combination are safe

... are used in anti-platelet therapy to help prevent restenosis (the reclogging of blood vessels after they have b...rial testing the efficacy of cilostazol to prevent restenosis after PCI. Earlier results from CREST showed a 35% relative risk reduction in restenosis from 34% to...

Stents and going with the flow

...fective when used in patients at increased risk of restenosis or at high risk of death if another revascularization procedure were to be performed. Otherwise, state the authors, their use is associated with a cost per quality-adjusted life-year that is similar to or higher than that of other accepted medical f...

New stroke prevention therapy as effective as invasive surgery

...complications as surgery (3%) and the same rate of restenosis after treatment (4%). "Today, these procedures are largely used for the heart, but I think that in the future they will be used for every artery and every part of the body," Dr. Piccoli said. The cost of the materials used in carotid an...

Drug-eluting stents adopted quickly, with early disparities

...ls have shown that these new stents can reduce the restenosis rate to single digits from the 20 to 30 percent rate of the older stents. The first drug-eluting stent received FDA approval in April, 2003. "Drug-eluting stents are truly breakthrough products in treating coronary artery disease, and in our analysis...

Loyola study shows drug-coated stent induces less inflammation than bare metal stent

... heart. The drug-coated stent reduces the risk of restenosis (renarrowing) of blood vessels after angioplasty, ...y have smaller arteries and thus a greater risk of restenosis of coronary vessels following angioplasty," he said. Participating in the inflammation study we...

Coronary stents do not improve long-term survival

...epeat procedures," Kandzari said. "We've know that restenosis has never been scientifically associated with increased mortality, but it has been associated with an increased need for revascularization and with a reduction in symptoms such as chest pain." Given these findings, Kandzari said physicians treating t...

Carbon monoxide from smoking helps keep arteries open following angioplasty

...thin the artery wall, which is a key factor in the restenosis process." In peripheral artery disease (PAD), a na...endovascular interventions for PAD will experience restenosis and will need to repeat the treatment within a year." Dr. Schillinger and his research team studied...

New technique for opening blocked carotid arteries significantly lowers complication risk

...ing the artery and cutting out the blockage. "For restenosis (a returned blockage in the same artery), there is... patients who undergo carotid endarterectomy after restenosis have major complications, including stroke and death, and up to 17 percent suffer cranial nerve pals...

CREST study finds cilostazol reduces restenosis by almost 40 percent

...indings showing the drug cilostazol reduces stent restenosis (the renarrowing of arteries following angioplasty... "Its effectiveness in the diabetic patient, where restenosis was reduced from 37 percent to 16.9 percent, is particularly exciting." Dr. Douglas and co-invest...

Study highlights efficacy of sirolimus stents to prevent restenosis for PTS with CAD

...stents (2.2 and 1.3 mm, respectively). The rate of restenosis was significantly reduced with sirolimus-eluting stents compared with control stents (6% and 42%, respectively). Fewer patients with sirolimus-eluting stents had major adverse cardiacevents at nine-months follow-up compared with patients given bare-m...

Stanford computer model shows bypass surgery more cost-effective than stents

...n eliminating the costs and detrimental effects of restenosis does not make stenting a better choice than bypass surgery for patients with blockages in more than one artery. "My hope is that physicians will say, 'Stents aren't the only good thing for my patient. There are other options that may result in better...

Pill may prevent stent complication that re-blocks arteries

... drug-eluting stents is associated with even lower restenosis rates, but neither radiation nor the special coate..., writes that finding an effective pill to prevent restenosis would "allow more flexibility in a choice of the type of stent to be used. It could also be used as...

Preliminary US study findings support excellent results with CYPHER Sirolimus-eluting Stent

...n-Man study. The 2% rate of angiographic in-stent restenosis representing a 94% reduction versus the control a...s. "The major reductions in angiographic in-stent restenosis and late lumen loss associated with the CYPHER Sirolimus-eluting Stent are proving to be remarkably ...

Repeat stenting not always durable

DALLAS, May 14 In-stent restenosis the re-narrowing of vessels that had been propped...ne at the time patients where treated for in-stent restenosis and again six months later. The measurement is called lumen volume index (LVI). Higher LVI means b...

Radiation rids arteries of re-narrowing for up to five years

...ation appeared to be a likely candidate to prevent restenosis and beat this cycle of repeat procedures because i...rs, fewer of the radiation patients came back with restenosis compared to the placebo group. Patients were examined at 6 months, 3 years, and 5 years. After 6 mo...

MMP enzymes play key role in stability and breakdown of atherosclerotic plaques

... occur naturally during atherosclerosis, or during restenosis following surgical interventions aimed at widening diseased arteries....

Molecular self-assembly techniques used to coat biomedical substrates

...ms incorporating the appropriate biochemicals, the restenosis can be inhibited. The initial results are promising, but we have more research to do to." "Prior to our biocompatible coatings work, our laboratory has been able to create via ESA nonlinear optical thin films incorporating polymer dyes, ceramic nanop...

New study of coated stent long-term results disappointing

...and one person died. At 12 months, 61 percent had restenosis and another person had a heart attack. The stent a...nt has a plastic sleeve and its possible that late restenosis could be the consequence of this sleeve, rather than a failure of the drug, says Colombo....

Diabetics at greatest risk of complications after re-opening arteries

... to prop open the artery reduces the incidence of restenosis following balloon angioplasty, although it still i... years. Van Belles team found that the amount of restenosis in the diabetics blood vessels six months after PTCA was associated with increased mortality most n...

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