Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...e cell.The signal initiates a chain of events that results in the burning of storedfat. Specifically, mice ...il 19 in the Journal of BiologicalChemistry. "Our results suggest that a class of drugs called B3 adrenergic receptoragonists might help in weight loss," said...Shark-Liver Substance May Slow Growth Of Brain Tumors
...blood vessels that nourish solid brain tumors. The results suggest that the substance, squalamine, named for the shark genus Squalus, may find a role with chemotherapy, radiation and surgery in treating brain cancer and other solid tumors in people, say scientists from Hopkins and Magainin Pharmaceuticals, w...DNA Imaging to Design Better Drugs
...ules. It'sfaster than traditional methods, and the results are direct andrelatively simple to interpret. "Our technique directly visualizes individual DNA molecules, whiletraditional techniques are indirect and inferential, sometimes givinginexplicable results," said Dr. Loren Williams, an associate profess...Digital Speech Analysis Tests Sobriety
...ngs) going through your vocal cords." Preliminary results show that intoxicated speech is marked by jumpycha...ly or slowly, loudly or softly. "Given her robust results in the differentiation of styles ofstressed speech, we thought that this type of analysis might show...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...o one knows what happens to it." Lee presented her results from in vitro testing during therecent Pittsburgh Conference on Analytical Chemistry. She is nowtesting her probes on live animals in collaboration withradiology professor Anthony McGoron who presented their workat the Society of Nuclear Medicine mee...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...nd remembering shapes, patterns and locations, the results showed. When not receiving testosterone, the men s...icantly better than those getting the placebo, the results showed. The tablets allowed the men to perform as well sexually as when they received testosterone i...Tacrolimus Stops Rejection Of Kidney Transplants
...multi-center trial to demonstrate such encouraging results for persistent kidney rejection. The study, which ...ve deterioration of the transplanted kidney. These results indicate that overall, tacrolimus therapy may reduce the 10 to 15 percent of kidneys that are lost t...Partial Liquid Breathing Improves Lung Function, Chances of Survival in Sick Preemies
...espiratory distress syndrome are now under way and results are promising, Leach said....Study Demonstrates Safety & Effectiveness Of Asthma Drug
...e use of medication for treating mild asthma. The results show that the commonly prescribed inhalant drug, a...ional Heart, Lung and Blood Institute (NHLBI). The results of the study were reported in the article, "Comparisonof Regularly Scheduled with As-Needed Use of A...A Surgical Semiconductor Laser With More Precision And Power
...power is forseveral to be used in tandem, but this results in poor beam quality. "Traditionally, with higher power you lose the ability to focus a semiconductor laser on its target," Marciantesays. "Rather than a single strong beam, you get three to five weaker beams, greatly diminishing the laser's pow...Stents Work Well, But Are Costly: Will Hospitals Continue To Use Them?
...an angioplasty that delivers a stent. Analyzingthe results in about 400 patients, he found that stenting costs about $13,000-- roughly $2,000 to $3,000 more than regular angioplasty. To many cardiologists and patients, that extra expense is well worthit, because inserting a stent structure in an artery ha...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
...can be partially restored, accordingto preliminary results from AIDS Clinical Trials Group (ACTG)315, support...l M. Lederman,M.D., plans to discuss these interim results in a late-breakersession at the Fourth Conference on Retroviruses and OpportunisticInfections in Was...NIAID Stops AIDS Study Prematurely Because Drug 'Cocktail' Boosts Survival
...udy even before all patients were enrolled because results were so dramatic. The University of North Carolin...er patients clinical benefits. These very exciting results renew our enthusiasm for this approach, which now clearly is the best treatment we have available." ...Laser Shown Effective In Patients Who Are Not Candidates For Bypass Surgery Or Angioplasty
...r conventional forms of treatment,according to the results of a recently completed multi-center clinical trial. A study of 198 patients, randomized to either the new laser therapyor continued treatment with heart medicines, found that 71 percent of thepatients treated with the laser showed significant ...Study Shows Gum Disease Increases Risk Of Future Heart Disease
...of the UB Department of Oral Biology, reported the results here today (Sunday, March 23) at the annual meeting of the International Association for Dental Research. "We have always suspected that periodontal disease was a true risk factor for cardiovascular disease, but our studies have been confounded ...ACTG Protocol 185 Enrollment Halted
...t Data and Safety Monitoring Board (DSMB) reviewed results from the first of four planned efficacy analyses. ...eborn infants, and one or more diagnostic HIV test results were available in 379 infants. The estimated overall rate of mother-to-infant HIV transmission was a......e presenting their scientific methods and clinical results this week at the Fifth Scientific Meeting and Exhi...olumbia. Lewin is encouraged by the early results because kidney cancer is so devastating. Most patients cannot withstand surgery and do not benefit f...Laser Offers Hope For Heart Patients With No Alternatives
... the laser system,which has demonstrated promising results for the eight patients treatedat the medical center since October. "The laser gives us another tool for helping patients for whom wecould do nothing else," said Duke surgeon Dr. James Lowe, who headsup the Duke investigation. "These patients...Researchers Gain Insights Into Drugs Used For Manic-Depression
...nd to be effective. Cliniciansdiscovered that best results often occurred by using a combination of bothdrugs, especially in patients who have a form of the disease that recursfrequently. "Lithium can be very effective but it can cause gastrointestinaland kidney problems, weight gain and grogginess,......rete similar germ-fighting compounds. Their results were published recently in the journal FEBS (Federation of European Biochemical Societies) Letters. The other study author was Michael Delannoy, an electron microscopist....