ACTG Protocol 185 Enrollment Halted
...ndependent Data and Safety Monitoring Board (DSMB) reviewed results from the first of four planned efficacy analyses. The protocol opened on October 13, 1993. By December 23, 1996, the date on which the study database was closed for the first efficacy analysis, 445 women had enrolled, 394 had delivered 402 ...Jefferson Researcher Finds New Digital X-Ray Technology May Cut Costs And Improve Patient Care
...ewark, Del. DirectRay, which is currently being reviewed by the U.S. Food and Drug Administration, will be formally unveiled Sunday, Nov. 30, at the 83rd Scientific Assembly and Annual meeting of the Radiological Society of North America meeting (RSNA) in Chicago. Dr. Shaber will also be p......n College of Cardiology. The four trials reviewed by the Duke researchers were called EPIC, IMPACT-II, GUSTO-IIb and PURSUIT. Researchers from the Cleveland Cliniccoordinated the EPIC trial, the other three were coordinated by the DukeClinical Research Institute, of which Mahaffey is a member. ...Studies Look At Threshold Effect Of Cholesterol-Lowering "Statin" Drugs
...y department at the Aker Hospital in Oslo, Norway, reviewed the findings of the Scandinavian Simvastatin Survival Study (4S) of 4,444 individuals with coronary heart disease and total cholesterol in the 210-310 mg/dL range. Individuals received either 20-40 mg simvastatin daily or a placebo for aboutfive year...UB Plants "Seeds" By Investing In Research Projects; Researchers Leverage Investment 14 Times Over
...er institutions. "Because we have these proposals reviewed by researchers all over the world, the faculty get valuable feedback about the quality of their proposals," he continued. In an era of shrinking federal dollars for research, internal funding will become more and more important, particularly because ...Earliest Warning Sign Indicates Need To Test For Condition Associated With Fetal Deaths
...actors for fetal death. Gugino and colleagues reviewed the records of 804 perinatal deaths that occurred in Children's Hospital of Buffalo, a regional perinatal center, between 1988 and 1996. Chorioamnionitis was found to be present in 243, or about one-third of these cases, as determined by analysis of ...Metrifonate, A New Alzheimer Drug, Helps Behavior Problems
...ng WashingtonUniversity School of Medicine. Morris reviewed the resulting data as anindependent scientist, without compensation from Bayer. Metrifonate belongs to a class of drugs called acetylcholinesterase(AChE) inhibitors. These drugs slow the breakdown of a chemical messenger calledacetylcholine, ......dustry. In recent months, data have been reviewed in three public sciencesymposiums on various type... findings and theoreticalmechanisms of action were reviewed in March 1997, epidemiology findings inJanuary 1998, and in vivo and clinical studies in April 199...International Panel Evaluates Testing For Drug Resistance In HIV
...in the treatment of HIV-relateddisease. The panel reviewed existing information from published reports,research conference presentations, basic and clinical research studies andinformation from the manufacturers of available resistance assays and metregularly over a six-month period to develop their report. ...Epilepsy Drug Found To Stop Cocaine's Effects In Animals
... several years. The Food & Drug Administration has reviewed its safety and effectiveness forpotential use in treating epilepsy in the U.S. It is expected to receive finalFDA approval for epilepsy use this fall. Today's publication is the culmination of more than twelve years ofinvestigation that sta...... about what happened during and after delivery and reviewed allmedical records. Three-quarters of the 41 extremely premature babies during the year wereresuscitated; 59 percent died, Doron said. Of those born at 24 weeks ...National Science Foundation Awards Knowledge And Distributed Intelligence Grants
.... Nearly 700 research proposals were received and reviewed by an advisory panel of 235 experts representing the full spectrum of scientific disciplines within the purview of the KDI initiative. "We were impressed with the number of excellent proposals," said Michael McCloskey, NSF's KDI coordinator. "I wis...6,000 Pharmaceutical Scientists Convene November 15-19 In San Francisco
... mistakes are currently being reviewed by the FDA. Impact of High Altitude on Drug Efficacy -- Those who enjoy traveling to exotic locations, beware. The latest research shows that staying at high altitudes for more than 24 hours ...World's Premier Pharmaceutical Scientists Share Latest R&D Findings
...rb the probability of mistakes are currently being reviewed by the FDA. Impact of High Altitude on Drug Efficacy -- Those who enjoy traveling to exotic locations, beware. The latest research shows that staying at high altitudes for more than 24 hours can alter the effect of drugs like Demerol, Lithium and e...Hypertension: Getting Pharmacists Involved Can Help
...prescribed medications. Pharmacists also reviewed patients' medication regimens and maderecommendations to their physicians about less expensive or better formulations. Overall, 55 percent of those who saw a consultant pharmacist achievedblood pressure control, compared with 20 percent of tho...Physicians Study Whether "Super-Aspirin" Prevents Alzheimer's
...ammation. The first ofthe drugs is currently being reviewed for the treatment ofarthritis and may be available next year. The drugs target cycloxygenase-2 or cox-2, an enzyme in thebody first discovered and cloned by a University team led by DonYoung and Kerry O'Banion. Scientists believe the enzyme is a...An Ergonomically Redesigned Analgesia Delivery Device Proves Safer And More Efficient
... describing problems with the Abbott PCA pump were reviewed for a randomly chosen year, 1993. An analysis of these reports showed that out of the cases where the device was known to be connected to the patient (308 cases), a majority of incidents, 86%, were caused by device malfunction (i.e., mechanical or el...Study Finds Olestra Chips Don't Generate Gastrointestinal Woes
...t substitute for use in snacks in January 1996 and reviewed itsapproval last June. A report on the new study is being published Tuesday (Feb.16) in the Annals of Internal Medicine, a medical journal. "Olestra is composed of sucrose, which is table sugar, and soybean oil,"said Dr. Robert Sandler, prof......alopportunities." Francis and his colleagues reviewed the progress of 35 school-age (K-8)children withprofound hearing loss. Prior to implantation, 22 attended special educationclasses full-time inpublic schools, five attended the Maryland School for the Deaf and eight were inspecialpreschool classes. A......data analyzedby Immunex. These data have not been reviewed by the U.S. Food and DrugAdministration (FDA) as part of an application for regulatory approval. LEUKINEis not indicated for use in HIV, however, the company has been workingaggressively since 1996 to evaluate the product's mechanism of action and r...