Tag: "rhesus" at medical news

UNC AIDS vaccine researchers awarded $12 million federal grant

...a test casesimian immunodeficiency virus (SIV). In rhesus macaque monkeys, SIV causes adisease that is similar to AIDS in humans. "The idea behind vaccination is to trick the body into thinking it's alreadyhad the disease once before. That's what vaccines do," Johnston explains. "Theypresent the body with...

Cedars-Sinai researchers present findings suggesting link between high soy diet and eventual developmental changes in children

...or female hormone levels at this time of life in a rhesus macaque, for example, can change the timing of puberty in males," said Dr. Hughes. "Concern is based on the expectation that animal models will be at least somewhat predictive of what occurs in humans. There is no reason to assume that there will be ...

OHSU scientists seek to advance the study of human disease by taking steps to clone identical monkeys through embryo splitting

...n empty eggshell. An egg was implanted in a female rhesus monkey, resulting in Tetra's birth. The research was conducted through funding by the National Center for Research Resources, a component of the National Institutes of Health, along with funding from the National Institute for Child Health and Huma...

Parenting, stress and your child's risk for alcoholism

...to calm themselves down." Higley's study looked at rhesus monkeys, which share between 90 to 95 percent of their genetic material with humans. These monkeys also have a similar adrenal system which, for the purposes of this study, means that they respond to stress like humans do. In addition, primates hav...

Sent naked into battle

... Diseases at Fort Detrick, Maryland. In the study, rhesus monkeys were given a vaccine similar to the one used for the US troops, and then inhaled large doses of anthrax spores. Anthrax is too dangerous for this test to be carried out in humans. The notes record that although the monkeys survived, they bec...

Safer estrogen targets painful intercourse in older women

...s vaginal stimulation or systemic action in female rhesus monkeys that do not produce estrogen. Depending on the outcome of this study, human studies of the new estrogen could begin within a year or two, they say. Another potential benefit of the Yale estrogen is treatment of wrinkles. Since the skin contai...

OHSU researcher presents findings on appetite-reducing hormone at neuroscience meeting

...ng-term PYY 3-36 treatment on animals, using obese rhesus macaque monkeys as a model."...

Study suggests that tomboys may be born, not made

...D., of City University in London "In both rats and rhesus monkeys, genetic female animals treated with testosterone during critical periods of prenatal or early postnatal life show increased levels of male-typical play behavior as juveniles." Hines and her co-authors note that girls with congenital adrenal...

Gel put springiness back into old lenses

...mi showed that replacing the contents of an ageing rhesus monkey's lens with silicone oil could restore its ...o the next step is to assess the technique in live rhesus monkeys, which have similar eyes to humans. This work should begin by the end of this year, Ho says,...

Promising West Nile virus vaccine protects monkeys

...ed two versions of the West Nile/dengue 4 virus in rhesus monkeys, one with the entire dengue virus RNA and one with some of the dengue RNA deleted. By doing so, they proved that deleting some of the dengue RNA weakened it even further. NIAID scientists gave one or the other of the two chimeric virus vaccin...

'Shifty-eyed' monkeys offer window into brain's social reflexes

...searchers compared the eye movements of humans and rhesus macaque monkeys when they were shown images of monkeys looking either to the left or right. The researchers would first concentrate the human or monkey test subjects' attention to the center of a computer screen by showing them a yellow square. The ...

Monkeys consciously control a robot arm using only brain signals

...hers at Duke University Medical Center have taught rhesus monkeys to consciously control the movement of a r...tal and parietal lobes of the brains of two female rhesus macaque monkeys. They implanted 96 electrodes in one animal and 320 in the other. The researchers re...

Animal model shows early promise for SARS vaccine

...fective in triggering an immune reaction among six rhesus macaques. A new form of coronavirus (SARS-CoV) was...ronavirus and injected it intramuscularly into six rhesus macaques; two other macaques received a dummy vaccine as a control. Booster injections were given 28...

Scientists find HIV-blocking protein in monkeys

...eam and lead author on the new paper, searched the rhesus monkey genome and isolated a stretch of DNA that encodes the TRIM5-alpha protein. In a series of experiments using lab-grown cells that either possessed or lacked TRIM5-alpha, the scientists determined that TRIM5-alpha is both necessary and sufficien...

New animal model for Alzheimer vaccine

...concept study, Gandy and colleagues vaccinated two rhesus monkeys with beta amyloid, a protein fragment considered a prime suspect in disrupting and destroying nerve cells in the Alzheimer brain. The vaccinated monkeys developed significant levels of antibodies to beta amyloid as well as high levels of bet...

Jefferson Alzheimer's vaccine shows promise in animal model

...and his colleagues tested the vaccine in four aged rhesus monkeys. Two monkeys were given beta-amyloid; the other two were given a placebo. Aging non-human primates develop some plaque, though less than a person with Alzheimer's, Dr. Gandy says. The vaccinated monkeys developed high levels of a...

OHSU scientists advance fertility preservation procedure

...edure called ovarian tissue transplant. The female rhesus monkey was born at the OHSU Oregon National Primate Research Center. Details of this breakthrough are printed in the March 11, 2004, edition of the journal Nature. "With some of the most successful but aggressive cancer treatments, such as chemothe...

Investigational drug may provide new option for preventing transplant organ rejection

... This pre-clinical course of investigation, using rhesus macaque monkeys, was crucial not only to the current clinical trial but to other planned studies. "The data from the primate studies as well as the current clinical trial have formed the basis of a new study to be conducted by Emory and the Immune To...

Yerkes researchers discover combination of drug therapies reduces cocaine use in primates

...nhibition was effective in limiting cocaine use in rhesus macaques who are trained to self-administer cocaine. "It appears DAT inhibition serves to substitute for cocaine, while SERT inhibition may limit the abuse potential of the medication," said Howell. "Our results, therefore, showing a combination of D...

The brain science behind 'A beautiful mind'

...o develop their findings, Glimcher and Dorris used rhesus monkeys to participate in a strategic conflict gam...se predictions with experiments on both humans and rhesus monkeys, and to examine in the monkeys whether there was evidence that decision-making became encode...

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