Little benefit from comprehensive assessment of older people in general practice
...of older people but it is essential that these are rigorously evaluated before their introduction as policy" In an accompanying commentary (p 1641), Andreas Stuck (University of Berne, Switzerland) and colleagues conclude: "Clearly, the trial's findings should inform the implementation of the UK National Servic...Can poor countries help rich countries contain drug costs?
...mitations on choice of drug may save money, but if rigorously applied, some patients will be affected. Drug lists also need integration into clinical guidelines, which can improve care but not necessarily cut cost, they add. For instance, in the United Kingdom, National Institute for Clinical Excellence guideli...NIH launches new study to compare prostate surgery and drugs
...never been compared. Further, there have been few rigorously conducted randomized trials of the minimally invasive surgical approaches. "Previous studies of TUMT and TUNA haven't looked at side-effects and symptom relief long-term but, after we've finished MIST, men and their doctors should be a lot...Complementary & alternative medicine use
...and multiple CAM therapies underscores the need to rigorously evaluate the safety, efficacy, and cost-effectiveness of these approaches, according to the study's lead author Hilary Tindle, Harvard Medical School (HMS) research fellow, and co-author David Eisenberg, director of the Division for Research and Educ...Controversial drug shown to act on brain protein to cut alcohol use
...linicians as a potent anti-addiction drug has been rigorously studied for the first time, confirming its ability to block alcohol craving in rodents, and clarifying how it works in the brain. The new research findings about the drug Ibogaine open the way for development of other drugs to reverse addiction witho...Suffering from fatigue, abdominal discomfort or bloody diarrhea?
...lon and rectum. Since none of the scales have been rigorously tested, experts in the field, especially those in clinical research, tend to use multiple disease activity indices, including those requiring endoscopy, to assess patients. With no gold standard in place to measure disease activity, Higgins and his c...New study tests amitriptyline for painful bladder syndrome
...tive treatment for patients. But until the drug is rigorously tested we won't know its true value in these syndromes," said Leroy M. Nyberg Jr., Ph.D., M.D., who oversees IC research sponsored by NIDDK. "And we'll never know if we are raising false hopes for patients, and unnecessarily spending health care doll...Regular cannabis may increase risk of stroke in young users
...otential of cannabis and its derivatives should be rigorously evaluated and the benefit to risk ratio taken into account before authorising their medical use," writes Dr Dominique Deplanque, of the Department of Pharmacology at the University of Lille....Patient knows best when it comes to ulcerative colitis, U-M study finds
...lon and rectum. Since none of the scales have been rigorously tested, experts in the field, especially those in clinical research, tend to use multiple disease activity indices, including those requiring endoscopy, to assess patients. With no gold standard in place to measure disease activity, Higgins and his c......is work is characterized by being meticulously and rigorously performed. His papers are a joy to read because of the completeness of his studies. As a result, the majority of his work has appeared in journals of the highest and first rank, including Cell, Journal of Biological Chemistry, Biochemistry, Journal o...